GILMAR DE SOUZA OSMUNDO JUNIOR

(Fonte: Lattes)
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Lattes
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Instituto Central, Hospital das Clínicas, Faculdade de Medicina - Médico
Instituto do Coração, Hospital das Clínicas, Faculdade de Medicina - Médico
LIM/57 - Laboratório de Fisiologia Obstétrica, Hospital das Clínicas, Faculdade de Medicina

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  • bookPart
    Cesárea
    (2020) YOSHIZAKI, Carlos Tadashi; OSMUNDO JUNIOR, Gilmar de Souza; PEREIRA, Pedro Paulo; FRANCISCO, Rossana Pulcineli Vieira; MIYADAHIRA, Seizo; MARTINELLI, Silvio; BUNDUKI, Victor
  • bookPart
    Analgesia e anestesia
    (2016) YOSHIZAKI, Carlos Tadashi; FITTIPALDI, Felipe Silva; OSMUNDO JUNIOR, Gilmar de Souza; FRANCISCO, Rossana Pulcineli Vieira; MARTINELLI, Silvio; BUNDUKI, Victor
  • article 2 Citação(ões) na Scopus
    Fetal gastroschisis: Maternal and fetal methylation profile
    (2021) FREITAS, Amanda Brasil de; FRANCISCO, Rossana Pulcineli Vieira; CENTOFANTI, Sandra Frankfurt; DAMASCENO, Jullian Gabriel; CHEHIMI, Samar Nasser; OSMUNDO JUNIOR, Gilmar de Souza; KULIKOWSKI, Leslie Domenici; BRIZOT, Maria de Lourdes
    Objective The purpose of this study was to describe the genomic deoxyribonucleic acid (DNA) methylation profile in fetuses with gastroschisis, determine whether the profile was inherited, and investigate any possible correlations with maternal risk factors. Method Genome-wide DNA methylation analysis of 96 blood samples was performed using the Illumina Human Methylation 850K BeadChip. The blood samples were collected as follows: 32 from the umbilical cord of fetuses with gastroschisis, 32 from their respective mothers, 16 from the umbilical cord of fetuses without malformation, and 16 from their respective mothers. Results The differential DNA methylation analysis showed a significant difference between the groups. The enrichment analysis resulted in 12 sites related to T-cell activation (p = 0.0128). The sites with different methylation status contained 10 genes, three of which were related to the beta-2-microglobulin gene. The methylation profile observed in the fetuses with gastroschisis was not inherited from the mothers. In addition, there was no association between maternal urinary tract infection, smoking, and alcohol use and different methylated sites. Conclusion We established the methylation profile of gastroschisis fetuses, which differs from that of normal fetuses. The profile was not inherited and did not correlate with maternal risk factors.
  • bookPart
    Doenças infecciosas parasitárias
    (2016) YOSHIZAKI, Carlos Tadashi; BAPTISTA, Fernanda Spadotto; OSMUNDO JUNIOR, Gilmar de Souza; LIN, Lawrence Hsu; BORTOLOTTO, Maria Rita de Figueiredo Lemos; PEREIRA, Pedro Paulo; COSTA, Rafaela Alkmin da; MARTINELLI, Silvio
  • bookPart
    Hemorragia pós-parto
    (2020) YOSHIZAKI, Carlos Tadashi; OSMUNDO JUNIOR, Gilmar de Souza; PEREIRA, Pedro Paulo; FRANCISCO, Rossana Pulcineli Vieira; MIYADAHIRA, Seizo; MARTINELLI, Silvio; BUNDUKI, Victor
  • bookPart
    Planejamento familiar
    (2020) YOSHIZAKI, Carlos Tadashi; OSMUNDO JUNIOR, Gilmar de Souza; PEREIRA, Pedro Paulo; FRANCISCO, Rossana Pulcineli Vieira; MIYADAHIRA, Seizo; MARTINELLI, Silvio; BUNDUKI, Victor
  • bookPart
    Distocias
    (2016) YOSHIZAKI, Carlos Tadashi; FITTIPALDI, Felipe Silva; OSMUNDO JUNIOR, Gilmar de Souza; FRANCISCO, Rossana Pulcineli Vieira; MARTINELLI, Silvio; BUNDUKI, Victor
  • bookPart
    Doenças hematológicas
    (2016) YOSHIZAKI, Carlos Tadashi; BAPTISTA, Fernanda Spadotto; OSMUNDO JUNIOR, Gilmar de Souza; LIN, Lawrence Hsu; BORTOLOTTO, Maria Rita de Figueiredo Lemos; PEREIRA, Pedro Paulo; COSTA, Rafaela Alkmin da; MARTINELLI, Silvio
  • bookPart
    Doenças endócrinas
    (2016) YOSHIZAKI, Carlos Tadashi; BAPTISTA, Fernanda Spadotto; OSMUNDO JUNIOR, Gilmar de Souza; LIN, Lawrence Hsu; BORTOLOTTO, Maria Rita de Figueiredo Lemos; PEREIRA, Pedro Paulo; COSTA, Rafaela Alkmin da; MARTINELLI, Silvio
  • bookPart
    Obesidade e gravidez
    (2020) YOSHIZAKI, Carlos Tadashi; TESTA, Carolina Burgarelli; PAGANOTI, Cristiane de Freitas; BAPTISTA, Fernanda Spadotto; OSMUNDO JUNIOR, Gilmar de Souza; LIN, Lawrence Hsu; GALLETTA, Marco Aurélio Knippel; BORTOLOTTO, Maria Rita de Figueiredo Lemos; PEREIRA, Pedro Paulo; COSTA, Rafaela Alkmin da; RIBEIRO, Renata Lopes; FRANCISCO, Rossana Pulcineli Vieira