RENATA HARUMI GOBBATO YAMASHITA
Projetos de Pesquisa
Unidades Organizacionais
Instituto Central, Hospital das Clínicas, Faculdade de Medicina
LIM/26 - Laboratório de Pesquisa em Cirurgia Experimental, Hospital das Clínicas, Faculdade de Medicina
LIM/26 - Laboratório de Pesquisa em Cirurgia Experimental, Hospital das Clínicas, Faculdade de Medicina
7 resultados
Resultados de Busca
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- Neurocysticercosis: challenges in pediatric neurosurgery practice(2023) YAMAKI, Vitor Nagai; TELLES, Joao Paulo Mota; YAMASHITA, Renata Harumi Gobbato; MATUSHITA, HamiltonPurposeNeurocysticercosis (NCC) is considered a neglected infectious disease, but the most common parasitic disease of the central nervous system (CNS). Due to oral tendencies in childhood, it is hypothesized that individuals are infected around this age and develop symptoms as lately as during young adulthood. Although it is considered a benign disease, it may cause great impact in the patient's quality of life due to epilepsy, visual symptoms, and hydrocephalus, which eventually requires frequent hospitalizations. The treatment of hydrocephalus is the main challenge for neurosurgeons.MethodsWe performed a concise review on neurocysticercosis in children and the main presentations of NCC in the neurosurgery practice and a systematic review on hydrocephalus secondary to extraparenchymal NCC.ResultsOur review showed a rate of complete resolution of hydrocephalus secondary to NCC of around 80% with the first attempt of surgical treatment combined with medication therapy. Endoscopic removal of the intraventricular cysts with third ventriculostomy was the most common treatment modality. Patients previously managed with ventricular shunts are likely to have worse outcomes and complications.ConclusionEndoscopic approach is the gold standard surgical treatment for hydrocephalus secondary to neurocysticercosis.
conferenceObject Efficacy, safety and cost analysis of the Sphera Pro Valve in the treatment of NPH patients(2022) REIS, Rodolfo C.; YAMASHITA, Renata H. G.; SOLLA, Davi J. F.; RAMIN, Lais F.; TEIXEIRA, Manoel J.; PINTO, Fernando C. G.- The impact of urgent neurosurgery on the survival of cancer patients(2020) TELLES, J.P.M.; YAMAKI, V.N.; YAMASHITA, R.G.; SOLLA, D.J.F.; PAIVA, W.S.; TEIXEIRA, M.J.; NEVILLE, I.S.Background: Patients with cancer are subject to all neurosurgical procedures of the general population, even if they are not directly caused by the tumor or its metastases. We sought to evaluate the impact of urgent neurosurgery on the survival of patients with cancer. Methods: We included patients submitted to neurosurgeries not directly related to their tumors in a cancer center from 2009 to 2018. Primary endpoints were mortality in index hospitalization and overall survival. Results: We included 410 patients, 144 went through elective procedures, functional (26.4%) and debridement (73.6%) and 276 urgent neurosurgeries were performed: one hundred and sixty-three ventricular shunts (59%), and 113 intracranial hemorrhages (41%). Median age was 56 (IQR = 24), 142 (51.4%) of patients were metastatic, with 101 (36.6%) having brain metastasis. In 82 (33.7%) of the urgent surgeries, the patient died in the same admission. Urgent surgeries were associated with mortality in index hospitalization (OR 3.45, 95% CI 1.93–6.15), as well as non-primary brain tumors (OR 3.13, 95% CI 1.48–6.61). Median survival after urgent surgeries was 102 days, compared to 245 days in the control group (Log rank, P < 0.01). Lower survival probability was associated with metastasis (HR 1.75, 95%CI 1.15–2.66) and urgent surgeries (HR 1.49, 95% CI 1.18–1.89). Within the urgent surgeries alone, metastasis predicted lower survival probability (HR 1.75, 95% CI 1.15–2.67). Conclusion: Conditions that require urgent neurosurgery in patients with cancer have a very poor prognosis. We present concrete data on the magnitude of several factors that need to be taken into account when deciding whether or not to recommend surgery. ©2020 Published by Scientific Scholar on behalf of Surgical Neurology International
- Psychiatric symptoms are frequent in idiopathic intracranial hypertension patients(2021) OLIVEIRA, Matheus Fernandes de; YAMASHITA, R. H. G.; SORTE JR., A. A. Boa; ROTTA, J. M.; NORREMOSE, K. A.; TEIXEIRA, M. J.; PINTO, F. C. G.Idiopathic intracranial hypertension (IIH) is a rare disease with an incidence rate of 0.5-2.0/100,000/year. Characteristic symptoms are headache and several degrees of visual impairment. Psychiatric symptoms in association with IIH are usually poorly described and underestimated. In this study, we evaluated IIH subjects to determine the association with psychiatric symptoms. We evaluated thirty consecutive patients with IIH submitted to neurosurgery from January 2017 to January 2020 in two Brazilian tertiary hospitals. They underwent clinical evaluation, obtaining medical history, comorbidities, body mass index (BMI-kg/m(2)), and applying Neuropsychiatric Inventory Questionnaire (NPI-Q). There were 28 females and 2 males. Ages ranged from 18 to 66 years old, with mean age of 37.97 +/- 12.78. Twenty-five (83%) presented comorbidities, being obese and having arterial hypertension the most frequent. Body mass index ranged from 25 to 35 kg/m(2)and mean value was 31 +/- 3.42. After application of Neuropsychiatric Interview, 26 of 30 presented psychiatric symptoms (86%). Depression-anxiety syndromes were reported in 25 patients (83%). Nighttime disturbances were reported by 14 subjects (46%). Appetite and eating disorders were described by 23 (76%). Psychiatric symptoms in association with IIH are usually poorly described and underestimated. In our sample, twenty-six out of 30 (86%) reported psychiatric symptoms. We highlight the high prevalence of psychiatric symptoms among IIH patients and the need of managing these patients with a multidisciplinary team, including psychiatrists.
conferenceObject Treatment of Idiopathic Normal Pressure Hydrocephalus With a Novel Programmable Valve With Gravitational Unit: Prospective Evaluation of Efficacy, Safety and Costs(2023) REIS, Rodolfo; YAMASHITA, Renata; SOLLA, Davi Jorge Fontoura; RAMIN, Lais; TEIXEIRA, Manoel Jacobsen Almeida de Oliveira; PINTO, Fernando Campos Gomes- YY Letter to the Editor Regarding ""Predictors of Nonroutine Discharge Disposition Among Parasagittal/Parafalcine Meningioma Patients""(2021) YAMASHITA, Renata Harumi Gobbato; NEVILLE, Iuri Santana; TEIXEIRA, Manoel Jacobsen; PAIVA, Wellingson Silva
- Malignant cerebral venous thrombosis in a transgender patient: intraoperative aspect of vein of Trolard thrombosis(2021) LOPES, Cesar Castello Branco; SILVA, Vinicius Trindade Gomes da; LUCIO, Jose Erasmo Dal Col; YAMASHITA, Renata Harumi Gobbato; COMERLATTI, Luiz Roberto; LUCATO, Leandro Tavares; FREUA, Fernando