SERGIO BRASIL TUFIK
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33 resultados
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- Do sleep disorders play a role in pre-eclampsia?(2014) TUFIK, S. B.; BERRO, L. F.; ANDERSEN, M. L.; TUFIK, S.
- Re: Safety and Efficacy of Testosterone Replacement Therapy in Adolescents with Klinefelter Syndrome Reply(2014) TUFIK, Sergio B.; BERRO, Lais F.; ANDERSEN, Monica L.; TUFIK, Sergio
- A systematic review on the role of infrared thermography in the Brown adipose tissue assessment(2020) BRASIL, Sergio; RENCK, Alessandra C.; MENECK, Franciele de; BRIOSCHI, Marcos L.; COSTA, Elaine F.; TEIXEIRA, Manoel J.Brown adipose tissue (BAT) is an endocrine adipose tissue with attributes to dissipate energy as heat in response to changes in temperature and diet. Infrared thermography (IRT) has been studied in recent years in the assessment of BAT thermogenesis, as an option to positron emission tomography - computed tomography (PET-CT), because of several advantages. We performed a systematic review on the use of IRT in BAT assessment. Comprehensive online search was performed in different databases. The QUADAS 2 tool was used to evaluate studies' quality. 12 studies fit the inclusion criteria, whereas only one of these was considered of low risk of bias. 10 studies were favorable to IRT appliance in BAT evaluation, observing elevation of supraclavicular skin temperature correlated with BAT activity. Studies were heterogeneous in design, and a meta-analysis was precluded. Further studies with similar methodologies are needed. Conclusion: Despite the large number of published methodologies, IRT is a promising method for detecting BAT activation. Current knowledge already allows a better understanding of thermography to improve and standardize the technique.
- Evaluation of cerebral hemodynamics by transcranial Doppler ultrasonography and its correlation with intracranial pressure in an animal model of intracranial hypertension(2022) SOARES, Matheus Schmidt; ANDRADE, Almir Ferreira de; BRASIL, Sergio; DE-LIMA-OLIVEIRA, Marcelo; BELON, Alessandro Rodrigo; BOR-SENG-SHU, Edson; NOGUEIRA, Ricardo de Carvalho; GODOY, Daniel Agustin; PAIVA, Wellingson SilvaBackground: Transcranial Doppler has been tested in the evaluation of cerebral hemodynamics as a non-invasive assessment of intracranial pressure (ICP), but there is controversy in the literature about its actual benefit and usefulness in this situation. Objective: To investigate cerebral blood flow assessed by Doppler technique and correlate with the variations of the ICP in the acute phase of intracranial hypertension in an animal model. Methods:An experimental animal model of intracranial hypertension was used. The experiment consisted of two groups of animals in which intracranial balloons were implanted and inflated with 4 mL (A) and 7 mL (B) for controlled simulation of different volumes of hematoma. The values of ICP and Doppler parameters (systolic [FVs], diastolic [FVd], and mean [FVm] cerebral blood flow velocities and pulsatility index [PI]) were collected during the entire procedure (before and during hematoma simulations and venous hypertonic saline infusion intervention). Comparisons between Doppler parameters and ICP monitoring were performed. Results: Twenty pigs were studied, 10 in group A and 10 in group B. A significant correlation between PI and ICP was obtained, especially shortly after abrupt elevation of ICP. There was no correlation between ICP and FVs, FVd or FVm separately. There was also no significant change in ICP after intravenous infusion of hypertonic saline solution. Conclusions:These results demonstrate the potential of PI as a parameter for the evaluation of patients with suspected ICP elevation.
- Estimation of intracranial pressure by ultrasound of the optic nerve sheath in an animal model of intracranial hypertension(2021) JENG, Brasil Chian Ping; ANDRADE, Almir Ferreira de; BRASIL, Sergio; BOR-SENG-SHU, Edson; BELON, Alessandro Rodrigo; ROBERTIS, Maira; DE-LIMA-OLIVEIRA, Marcelo; RUBIANO, Andres Mariano; GODOY, Daniel Agustin; TEIXEIRA, Manoel Jacobsen; PAIVA, Wellingson SilvaBackground: Ultrasound of the optic nerve sheath diameter (ONSD) has been used as a non-invasive and cost-effective bedside alternative to invasive intracranial pressure (ICP) monitoring. However, ONSD time-lapse behavior in intracranial hypertension (ICH) and its relief by means of either saline infusion or surgery are still unknown. The objective of this study was to correlate intracranial pressure (ICP) and ultrasonography of the optic nerve sheath (ONS) in an experimental animal model of ICH and deter-mine the interval needed for ONSD to return to baseline levels. Methods: An experimental study was conducted on 30 pigs. ONSD was evaluated by ultrasound at differ-ent ICPs generated by intracranial balloon inflation, saline infusion, and balloon deflation, and measured using an intraventricular catheter. Results: All variables obtained by ONS ultrasonography such as left, right, and average ONSD (AON) were statistically significant to estimate the ICP value. ONSD changed immediately after balloon inflation and returned to baseline after an average delay of 30 min after balloon deflation (p = 0.016). No statistical sig-nificance was observed in the ICP and ONSD values with hypertonic saline infusion. In this swine model, ICP and ONSD showed linear correlation and ICP could be estimated using the formula:-80.5 + 238.2 x AON. Conclusion: In the present study, ultrasound to measure ONSD showed a linear correlation with ICP, although a short delay in returning to baseline levels was observed in the case of sudden ICH relief.
- Better Understanding of Bariatric Surgery Outcomes Through Sleep(2014) TUFIK, Sergio B.; BERRO, Lais F.; ANDERSEN, Monica L.; TUFIK, Sergio
conferenceObject The Lausanne NoSAS score: a simple and reliable screening tool for sleep apnea(2016) HABA-RUBIO, J.; MARTI-SOLER, H.; HIROTSU, C.; TOBBACK, N.; TUFIK, S. B.; TUFIK, S.; TAFTI, M.; BITTENCOURT, L.; HEINZER, R.- Brain Death Diagnostic Security is Over Organ Donation(2021) BRASIL, Sergio
conferenceObject INTRACRANIAL COMPLIANCE CONCEPTS AND ASSESSMENT OF TRAUMATIC BRAIN INJURY: A SCOPING REVIEW(2022) ZAMBETTA, Rafaella Mendes; OCAMOTO, Gabriela Nagai; FRIGIERI, Gustavo; HAYASHI, Cintya Yukie; BRASIL, Sergio; RABELO, Nicollas Nunes; RUSSO, Thiago Luiz- Assessing ultrasonographic optic nerve sheath diameter in animal model with anesthesia regimens(2022) AZEVEDO, Maira de Robertis; DE-LIMA-OLIVEIRA, Marcelo; BELON, Alessandro Rodrigo; BRASIL, Sergio; TEIXEIRA, Manoel Jacobsen; PAIVA, Wellingson Silva; BOR-SENG-SHU, EdsonPurpose: To determine the normal optical nerve sheath (ONS) diameter ultrasonography (ONSUS) and evaluate the possible effects of drugs on ONS diameter during anesthetic induction in healthy pigs. Methods: Healthy piglets were divided into three groups: a control group, that received xylazine and ketamine (X/K); other that received xylazine, ketamine and propofol (X/K/P); and a third group that received xylazine, ketamine, and thiopental (X/K/T). The sheath diameter was assessed by ultrasonography calculating the average of three measurements of each eye from the left and right sides. Results: 118 animals were anesthetized (49 X/K 33 X/K/P and 39 X/K/T). Mean ONS sizes on both sides in each group were 0.394 +/- 0.048 (X/K), 0.407 +/- 0.029 (X/K/P) and 0.378 +/- 0.042 cm (X/K/T) (medians of 0.400, 0.405 and 0.389, respectively). The ONS diameter varied from 0.287-0.512 cm (mean of 0.302 +/- 0.039 cm). For group X/K, the mean diameter was 0.394 +/- 0.048 cm. Significant differences in ONS sizes between the groups P and T (X/K/P > X/K/T, p = 0.003) were found. No statistically significant differences were detected when other groups were compared (X/K = X/K/P, p = 0.302; X/K = X/K/T, p = 0.294). Conclusion: Sedation with thiopental lead to significative ONS diameter reduction in comparison with propofol. ONSUS may be useful to evaluate responses to thiopental administration.