VINICIUS TRINDADE GOMES DA SILVA

(Fonte: Lattes)
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Lattes
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Instituto Central, Hospital das Clínicas, Faculdade de Medicina - Médico
LIM/45 - Laboratório de Fisiopatologia Neurocirúrgica, Hospital das Clínicas, Faculdade de Medicina

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Agora exibindo 1 - 4 de 4
  • article 0 Citação(ões) na Scopus
    Bevacizumab for the Treatment of High-Grade Meningiomas: Is There New Evidence? [Letter]
    (2022) SILVA, Vinicius Trindade Gomes da; GEBRIN, Thiago; PAIVA, Wellingson Silva
  • article 1 Citação(ões) na Scopus
    Loss of an eye to mucormycosis following corticosteroid therapy for COVID-19
    (2022) RODRIGUES, M. G.; SEKIGUCHI, W. K.; GONçALVES, S.; CASAL, Y. R.; FRASSETTO, F. P.; SILVA, V. T. G. da; SANTO, M. P. D. E.; MAGRI, M. M. C.
    Mucormycosis is a rare, sometimes severe fungal infection that has emerged as a possible complication of COVID-19. We report a case of a non-diabetic, apparently immunocompetent patient diagnosed with rhino-orbital-cerebral mucormycosis shortly after COVID-19 treatment with dexamethasone. The patient received optimized systemic antifungal therapy and extensive surgical treatment. So far, four months after the last hospital discharge, the patient has been in good general condition. This case is a dramatic reminder that beneficial corticosteroid therapy in general inevitably carries a risk of opportunistic infection, and corticosteroid therapy for COVID-19 risks orbital-rhinocerebral mucormycosis that clinicians should watch for with vigilance. © 2021 The Author(s).
  • article 5 Citação(ões) na Scopus
    Spheno-orbital meningiomas: Is orbit reconstruction mandatory? Long-term outcomes and exophthalmos improvement
    (2022) SANTOS, A. G. dos; PAIVA, W. S.; ROZ, L. M. da; SANTO, M. P. do Espirito; TEIXEIRA, M. J.; FIGUEIREDO, E. G.; SILVA, V. T. G. da
    Background: Meningiomas correspond to one-third of all primary central nervous system tumors. Approximately 9% of them are spheno-orbital meningiomas (SOMs), presenting significant clinical symptoms as visual impairment and orbital esthetics. This article aims to evaluate exophthalmos’ improvement in a surgical series without orbital reconstruction. Methods: We consecutively included all patients diagnosed with SOM, admitted to a single institution for 10 years. Surgical resection was the standard of care, associated or not with adjuvant radiation therapy. The radiological investigation included preoperative and postoperative head CT or MRI. We quantified proptosis through imaging. Results: Forty patients composed this series, 87.5% were female. Proptosis was the most common presentation (90%), followed by decreased visual acuity (65%), motility deficit (20%), and headache (20%). Gross total resection was achieved in 65% of the procedures. In late outcomes, 78% of the patients maintained or improved visual acuity and 85% maintained or improved headache. Proptosis significantly improved after surgery and along with the follow-up (P < 0.001). Ten patients were submitted to adjuvant RT, six of them after a subtotal resection. All patients of this subgroup had proptosis. It was observed a higher frequency of worse in visual acuity in patients submitted to RT (71% vs. 28%, P = 0.038). Conclusion: Resection of SOM was sufficient to stop the evolution of visual deficit and allowed the improvement of proptosis. Orbital reconstruction does not seem to be an essential step in reducing enophthalmos. ©2022 Published by Scientific Scholar on behalf of Surgical Neurology International
  • article 0 Citação(ões) na Scopus
    Retrosigmoid versus middle fossa approach for hearing and facial nerve preservation in vestibular schwannoma surgery: A systematic review and comparative meta-analysis
    (2024) PALAVANI, Lucca B.; BATISTA, Savio; ANDREAO, Filipi Fim; OLIVEIRA, Leonardo de Barros; SILVA, Guilherme Melo; KOESTER, Stefan; BARBIERI, Joao F.; BERTANI, Raphael; SILVA, Vinicius Trindade Gomes da; ACIOLY, Marcus; PAIVA, Wellingson S.; ANDRADE, Erion J. De; RASSI, Marcio S.
    Background: Vestibular schwannomas (VS) are benign tumors arising from vestibular nerve's Schwann cells. Surgical resection via retrosigmoid (RS) or middle fossa (MF) is standard, but the optimal approach remains debated. This meta-analysis evaluated RS and MF approaches for VS management, emphasizing hearing preservation and Cranial nerve seven (CN VII) outcomes stratified by tumor size. Methods: Systematic searches across PubMed, Cochrane, Web of Science, and Embase identified relevant studies. Hearing and CN VII outcomes were gauged using the American Academy of Otolaryngology-Head and Neck Surgery, Gardner Robertson, and House-Brackmann scores. Results: Among 7228 patients, 56 % underwent RS and 44 % MF. For intracanalicular tumors, MF recorded 38 % hearing loss, compared to RS's 54 %. In small tumors (<1.5 cm), MF showed 41 % hearing loss, contrasting RS's lower 15 %. Medium-sized tumors (1.5 cm-2.9 cm) revealed 68 % hearing loss in MF and 55 % in RS. Large tumors (>3 cm) were only reported in RS with a hearing loss rate of 62 %. Conclusion: Conclusively, while MF may be preferable for intracanalicular tumors, RS demonstrated superior hearing preservation for small to medium-sized tumors. This research underlines the significance of stratified outcomes by tumor size, guiding surgical decisions and enhancing patient outcomes.