GLAUCO FERNANDES SAES
Projetos de Pesquisa
Unidades Organizacionais
Instituto do Câncer do Estado de São Paulo, Hospital das Clínicas, Faculdade de Medicina - Médico
LIM/02 - Laboratório de Anatomia Médico-Cirúrgica, Hospital das Clínicas, Faculdade de Medicina
LIM/02 - Laboratório de Anatomia Médico-Cirúrgica, Hospital das Clínicas, Faculdade de Medicina
3 resultados
Resultados de Busca
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- Validation of a Brazilian Portuguese Version of the Walking Estimated-Limitation Calculated by History (WELCH)(2016) CUCATO, Gabriel Grizzo; CORREIA, Marilia de Almeida; FARAH, Breno Quintella; SAES, Glauco Fernandes; LIMA, Aluisio Henrique de Andrade; RITTI-DIAS, Raphael Mendes; WOLOSKER, NelsonBackground: The Walking Estimated-Limitation Calculated by History (WELCH) questionnaire has been proposed to evaluate walking impairment in patients with intermittent claudication (IC), presenting satisfactory psychometric properties. However, a Brazilian Portuguese version of the questionnaire is unavailable, limiting its application in Brazilian patients. Objective: To analyze the psychometric properties of a translated Brazilian Portuguese version of the WELCH in Brazilian patients with IC. Methods: Eighty-four patients with IC participated in the study. After translation and back-translation, carried out by two independent translators, the concurrent validity of the WELCH was analyzed by correlating the questionnaire scores with the walking capacity assessed with the Gardner treadmill test. To determine the reliability of the WELCH, internal consistency and test-retest reliability with a seven-day interval between the two questionnaire applications were calculated. Results: There were significant correlations between the WELCH score and the claudication onset distance (r = 0.64, p = 0.01) and total walking distance (r = 0.61, p = 0.01). The internal consistency was 0.84 and the intraclass correlation coefficient between questionnaire evaluations was 0.84. There were no differences in WELCH scores between the two questionnaire applications. Conclusion: The Brazilian Portuguese version of the WELCH presents adequate validity and reliability indicators, which support its application to Brazilian patients with IC.
- Barriers and Levels of Physical Activity in Patients With Symptomatic Peripheral Artery Disease: Comparison Between Women and Men(2019) SOUSA, Adilson Santos Andrade de; CORREIA, Marilia A.; FARAH, Breno Quintella; SAES, Glauco; ZERATI, Antonio Eduardo; PUECH-LEAO, Pedro; WOLOSKER, Nelson; CUCATO, Gabriel G.; RITTI-DIAS, Raphael M.This cross-sectional study compared physical activity levels and barriers between 212 men and women with symptomatic peripheral artery disease. Physical activity was objectively measured by an accelerometer. Barriers to physical activity were obtained using a validated questionnaire. Women reported higher amounts of light physical activity (p <.001) and lower moderate-vigorous physical activity (p < .001) than men. Women more often reported barriers such as ""not having anyone to accompany"" (p = .006), ""lack of money"" (p = .018), ""fear of falling or worsening the disease"" (p = .010), ""lack of security"" (p = .015), ""not having places to sit when feeling leg pain"" (p = .021), and ""difficulty in getting to a place to practice physical activity"" (p = .015). In conclusion, women with symptomatic peripheral artery disease presented with lower amounts of moderate-vigorous activity and more barriers to activity than men. Strategies to minimize the barriers, including group actives and nonpainful exercises, are recommended for women with peripheral artery disease.
- Calf Muscle Oxygen Saturation during 6-Minute Walk Test and Its Relationship with Walking Impairment in Symptomatic Peripheral Artery Disease(2018) ANDRADE-LIMA, Aluisio; CUCATO, Gabriel G.; DOMINGUES, Wagner J. R.; GERMANO-SOARES, Antonio H.; CAVALCANTE, Bruno R.; CORREIA, Marilia A.; SAES, Glauco F.; WOLOSKER, Nelson; GARDNER, Andrew W.; ZERATI, Antonio E.; RITTI-DIAS, Raphael M.Background: Impaired microcirculation is associated with poor walking capacity in symptomatic peripheral artery disease (PAD) patients during treadmill test; however, this test does not simulate the efforts of daily walking of these patients. Thus, the aim of the study was to describe the microcirculation responses during a 6-minute walk test (6MWT) and to analyze the relationship between microcirculation indicators and walking impairment in symptomatic PAD patients. Methods: Thirty-four patients were included (mean age = 67.6 +/- 11.2 years). Their clinical characteristics were collected, and they performed a 6MWT, in which the initial claudication distance (ICD) and total walking distance (TWD) were recorded. During and after the 6MWT, calf muscle oxygen saturation (StO(2)) parameters were monitored continuously to measure microcirculation behavior. The association between calf muscle StO(2) parameters and walking impairment were analyzed by Pearson or Spearman correlations. Results: Walking impairment was not associated with any StO(2) parameters during exercise. In contrast, after 6MWT, recovery time of StO(2) (r = -0.472, P = 0.008) and recovery time to maximal StO(2) (r = -0.402, P = 0.019) were negatively correlated with ICD. Furthermore, the distance walked under claudication symptoms (ATWD-ICD) was positively correlated with recovery time to maximal StO(2) (r = 0.347, P = 0.048). Conclusions: In symptomatic PAD patients, shorter ICD values during a 6MWT are associated with a delayed recovery in calf muscle StO(2) after exercise. Calf muscle StO(2) parameters decrease subtly during 6MWT, suggesting that the degree of ischemia in the calf muscle during ground walking, simulating efforts of the daily walking, is relatively low.