FERNANDA MARIA SILVEIRA SOUTO

Índice h a partir de 2011
2
Projetos de Pesquisa
Unidades Organizacionais
LIM/33 - Laboratório de Oftalmologia, Hospital das Clínicas, Faculdade de Medicina

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Agora exibindo 1 - 10 de 17
  • article 2 Citação(ões) na Scopus
    Comparação das medidas refratométricas através da utilização do Photoscreener 2win® e da retinoscopia manual em pré-escolares assintomáticos
    (2021) GONÇALVES, Bruno Viana; CARVALHO, Keila Miriam Monteiro de; MINGUINI, Nilza; ALVES, Milton Ruiz; SOUTO, Fernanda Maria
    ABSTRACT Objective: Evaluate the sensitivity, specificity e accuracy of the ocular refraction measured by the 2WIN® photoscreener as a screening method to identify children in need of spectacles prescription according to the criteria published by the Brazilian Society of Pediatric Ophthalmology (BSPO) in asymptomatic children, 6 to 36 months old, and determine the impact of cycloplegia in the sensitivity, specificity and accuracy of this method. Methods: One hundred seventy-eight (178) eyes of asymptomatic children between the ages of 6 and 36 months have been submitted to ocular refraction measurements by the gold-standard method, the manual retinoscopy under cycloplegia, and the method been tested, the 2WIN® photoscreening, both before and under cycloplegia. Results: The 2WIN® photoscreener before cycloplegia was able to identify those patients in need of spectacles prescription according to the criteria published by the BSPO with 100% sensitivity, 93.18% specificity and 93.26% accuracy, when compared to the manual retinoscopy under cycloplegia. The 2WIN® photoscreener under cycloplegia maintained a sensitivity of 100%, but increased specificity to 96.59% and accuracy to 96.63%. Conclusion: The 2WIN® photoscreener before cycloplegia showed high sensitivity, specificity, and accuracy in detection of patients in need of spectacles prescription according to the criteria published by the BSPO in the tested population, with minor increase in specificity and accuracy when the measurements were performed under cycloplegia.
  • article 1 Citação(ões) na Scopus
    Vogt-Koyanagi-Harada disease after discontinuation of systemic treatment
    (2022) SOUTO, Fernanda M. S.; LAVEZZO, Marcelo M.; OYAMADA, Maria K.; YAMAMOTO, Joyce H.
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    Vogt-Koyanagi-Harada disease (VKHD) after systemic treatment discontinuation
    (2021) SOUTO, Fernanda Maria Silveira; MISSAKA, Ruy Felippe Brito Goncalves; LAVEZZO, Marcelo Mendes; NOBREGA, Priscilla Figueiredo Campos; SAKATA, Viviane Mayumi; OYAMADA, Maria Kiyoko; HIRATA, Carlos Eduardo; YAMAMOTO, Joyce H.
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    Association between visual function and quality of life in patients with Vogt-Koyanagi-Harada disease
    (2018) TAKIUTI, J. H. Yamamoto; MISSAKA, R. F.; SOUTO, F. M.; MARCHIORI, B. M.; CAETANO, V. M.; TAKIUTI, J. T.; LAVEZZO, M. M.; OYAMADA, M. K.; HIRATA, C. E.
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    Retinal vasculitis (RV) in pediatric population: case series
    (2020) GIAMPIETRO, Barbara; SOUTO, Fernanda Maria Silveira; TAKIUTI, Julia Tieme; CAMPOS, Lucia Maria Arruda; HIRATA, Carlos Eduardo; YAMAMOTO, Joyce H.
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    Changes in quality of life (QoL) in a 24-month interval in patients with non-acute Vogt-Koyanagi-Harada disease (VKHD)
    (2022) SOUTO, Fernanda Maria Silveira; MISSAKA, Ruy Felippe; LAVEZZO, Marcelo Mendes; NOBREGA, Priscilla Figueiredo; SAKATA, Viviane Mayumi; MAGALHAES, Breno Marchiori; CAETANO, Victor Marcos Couto; TAKIUTI, Julia Thiemi; OYAMADA, Maria Kiyoko; HIRATA, Carlos Eduardo; YAMAMOTO, Joyce H.
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    Retinal vasculitis (RV) in acute and non-acute Vogt-Koyanagi-Harada disease (VKHD): a cross-sectional study with multimodal analysis
    (2020) MISSAKA, Ruy F. B. G.; SOUTO, Fernanda Maria Silveira; LAVEZZO, Marcelo Mendes; SAKATA, Viviane Mayumi; NOBREGA, Priscilla Figueiredo Campos da; OYAMADA, Maria Kiyoko; HIRATA, Carlos Eduardo; YAMAMOTO, Joyce H.
  • article 1 Citação(ões) na Scopus
    Associations between functional and structural measurements in non-acute Vogt-Koyanagi-Harada disease
    (2021) SOUTO, Fernanda Maria Silveira; MISSAKA, Ruy Felippe Brito Goncalves; LAVEZZO, Marcelo Mendes; SAKATA, Viviane Mayumi; OYAMADA, Maria Kiyoko; HIRATA, Carlos Eduardo; YAMAMOTO, Joyce Hisae
    Purpose To evaluate associations between functional and structural measurements in patients with non-acute VKHD. Methods In this cross-sectional study, 16 non-acute VKHD patients (32 eyes; 14 female) were evaluated with multifocal electroretinogram (mfERG), standardized automated perimetry (SAP) and optical coherence tomography (OCT)examinations. All included patients had a minimum 12 months of follow-up from acute onset and were participants of an ongoing prospective study since acute phase with systematic clinical imaging evaluations and electroretinogram examinations within a predefined treatment. Age- and gender-matched controls were included. Main outcomes were functional and structural abnormalities and their correlation; secondary outcome was correlation of these findings with clinical characteristics, including fundus abnormalities. Results SAP and mfERG parameters were significantly worse in patients than in controls. Fourteen eyes (43.7%) had disrupted ellipsoid zone (EZ); visual acuity (VA) was similar between eyes with intact or disrupted EZ. Eyes with intact and disrupted EZ differed significantly concerning N1 and P1 amplitudes and N1 peak time values on mfERG and mean sensitivity (MS), central sensitivity (CS), foveal threshold, visual field index, mean deviation (MD) and pattern standard deviation values on SAP. The area under the curve on receiver operating curves for P1 amplitude was 0.81 (cut-off value = 34.7 nV/deg(2)) and for MD value was 0.84 (cut-off value = -5.2 dB). Central retinal thickness (CRT) significantly correlated with N1 and P1 amplitudes and P1 peak time values on mfERG (r = 0.354, r = 0.442 and r = -0.405, respectively) and MD, MS, CS and fovea threshold (log values) on SAP (r = 0.372, r = 0.406, r = 0.431 and r = 0.414, respectively). Statistically significant associations were found with the presence of peripapillary atrophy and recurrent anterior uveitis with a worse MD value (p = 0.004 and p < 0.001, respectively). Conclusion In non-acute VKHD, disrupted EZ and reduced CRT were correlated with impaired mfERG and SAP parameters, even in patients with good VA.
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    Analysis of pattern and clinical features of pediatric uveitis cases at a tertiary referral center in Sao Paulo, Brazil
    (2018) GIAMPIETRO, Barbara; SOUTO, Fernanda Maria Silveira; TAKIUTI, Julia Thiemi; CAMPOS, Lucia Maria Arruda; HIRATA, Carlos Eduardo; YAMAMOTO, Joyce H.
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    Bacillary layer detachment in Vogt-Koyanagi-Harada disease: a biomarker with prognostic value
    (2022) MISSAKA, Ruy Felippe; GOLDBAUM, Mauro; MACHADO, Cleide Guimaraes; SOUTO, Fernanda Maria Silveira; NOBREGA, Priscilla Figueiredo; LAVEZZO, Marcelo Mendes; SAKATA, Viviane Mayumi; OYAMADA, Maria Kiyoko; HIRATA, Carlos Eduardo; YAMAMOTO, Joyce H.