VITOR MASSARO TAKAMATSU SAGAE

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LIM/55 - Laboratório de Urologia, Hospital das Clínicas, Faculdade de Medicina

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  • conferenceObject
    FLEXIBLE ENDOSCOPIC ROBOTIC RECTAL ESD
    (2021) SOUZA, Thiago F.; NETO, Manoel Galvao; SAGAE, Vitor M.; GRECCO, Eduardo; QUADROS, Luiz G.; WILSON, Erik B.; WILSON, Todd; MALUF-FILHO, Fauze
  • article 0 Citação(ões) na Scopus
    The feared postdilation complication in caustic esophageal stenosis: combined endoscopic and surgical treatment
    (2021) SAGAE, Vitor Massaro Takamatsu; RIBEIRO, Igor Braga; PONTE NETO, Alberto Machado da; MATUGUMA, Sergio Eiji; CHENG, Spencer; SANTOS, Marcos Eduardo Lera dos; MOURA, Eduardo Guimaraes Hourneaux de
  • article 13 Citação(ões) na Scopus
    Câncer gástrico em adultos jovens: um grupo de pior prognóstico?
    (2019) RAMOS, Marcus Fernando Kodama Pertille; PEREIRA, Marina Alessandra; SAGAE, Victor Masaro Takamatsu; MESTER, Marcelo; MORRELL, André Luiz Gioia; DIAS, Andre Roncon; ZILBERSTEIN, Bruno; RIBEIRO JUNIOR, Ulysses; CECCONELLO, Ivan
    ABSTRACT Objective: to evaluate the clinical and pathological characteristics and survival of young patients with gastric cancer, regardless of the intention of treatment. Methods: we conducted a retrospective analysis of all gastric cancer patients undergoing any surgical treatment between 2008 and 2017. We considered patients under 45 years old as young adults and those over 45 years old, as of advanced age. Results: of the 875 patients evaluated, 84 (9.6%) were young adults and 791 (90.4%) were older. Younger patients were associated with female gender (p<0.001), lower Charlson score (p=0.002), ASA I/II (p<0.001), diffuse Lauren type (p<0.001) and poorly differentiated tumors (p<0.001). There was no difference between groups regarding treatment intention (palliative versus curative) (p=0.267) and cTNM clinical stage (p=0.120). Disease-free survival was worse in younger individuals (p=0.049), but overall survival was similar between groups (p=0.578). Multivariate analysis identified total gastrectomy, pT3/T4, pN+, and diffuse Lauren type as prognostic factors associated with worse disease-free survival and overall survival. Age was not an independent factor associated with worse prognosis. Conclusion: although younger patients had lower disease-free survival, overall survival was similar between groups, and age was not a significant independent prognostic factor.
  • article 14 Citação(ões) na Scopus
    Pain relief in chronic pancreatitis: endoscopic or surgical treatment? a systematic review with meta-analysis
    (2021) MENDIETA, Pastor Joaquin Ortiz; SAGAE, Vitor Massaro Takamatsu; RIBEIRO, Igor Braga; MOURA, Diogo Turiani Hourneaux de; SCATIMBURGO, Maria Vitoria Cury Vieira; HIRSCH, Bruno Salomao; ROCHA, Rodrigo Silva de Paula; VISCONTI, Thiago Arantes de Carvalho; SANCHEZ-LUNA, Sergio A.; BERNARDO, Wanderley Marques; MOURA, Eduardo Guimaraes Hourneaux de
    Background and aims Pain is one of the consequences of chronic pancreatitis (CP) that has the greatest impact on the quality of life of patients. Endoscopic and surgical interventions, by producing a decrease in intraductal pancreatic pressure, can provide pain relief. This is the first systematic review that includes only randomized clinical trials (RTCs) comparing outcomes in the short-term (less than 2 years) and long-term (more than 2 years) between these two types of interventions. Material and methods A comprehensive search of multiple electronic databases to identify RTCs comparing short and long-term pain relief, procedural complications, and days of hospitalization between endoscopic and surgical interventions was performed following the PRISMA guidelines. Results Three RCTs evaluating a total of 199 patients (99 in the endoscopy group and 100 in the surgery group) were included in this study. Surgical interventions provided complete pain relief, with statistical difference, in the long-term (16,4% vs 35.7%; RD 0.19; 95% CI 0.03-0.35; p = 0.02; I2 = 0%), without significant difference in short-term (17.5% vs 31.2%; RD 0.14; 95% CI -0.01-0.28; p = 0.07; I2 = 0%) when compared to endoscopy. There was no statistical difference in short-term (17.5% vs 28.1%; RD 0.11; 95% CI -0.04-0.25; p = 0.15; I2 = 0%) and long-term (34% vs 41.1%; RD 0.07; 95% CI -0.10-0.24; p = 0.42; I2 0%) in partial relief of pain between both interventions. In the short-term, both complications (34.9% vs 29.7%; RD 0.05; 95% CI -0.10-0.21; p = 0.50; I2 = 48%) and days of hospitalization (MD -1.02; 95% CI -2.61-0.58; p = 0.21; I2 = 0%) showed no significant differences. Conclusion Surgical interventions showed superior results when compared to endoscopy in terms of complete long-term pain relief. The number of complications and length of hospitalization in both groups were similar.
  • conferenceObject
    GASTRIC PERORAL ENDOSCOPIC MYOTOMY (G-POEM) IN THE TREATMENT OF REFRACTORY GASTROPARESIS: CASE SERIES AND LITERATURE REVIEW
    (2019) PONTE, Alberto M. da; SAGAE, Vitor M.; MORITA, Flavio H.; MATSUBAYASHI, Carolina O.; MINATA, Mauricio K.; MOURA, Eduardo T.; SAKAI, Paulo; MOURA, Eduardo G. de; CHAVES, Dalton
  • conferenceObject
    EUS VERSUS ERCP FOR PRIMARY DRAINAGE OF MALIGNANT BILIARY OBSTRUCTION: A SYSTEMATIC REVIEW AND META-ANALYSIS BASED ON RANDOMIZED TRIALS
    (2019) LOGIUDICE, Fernanda P.; BERNARDO, Wanderlei M.; GALETTI, Facundo; FUNARI, Mateus P.; SAGAE, Vitor M.; MATSUBAYASHI, Carolina O.; BRUNALDI, Vitor O.; MATUGUMA, Sergio E.; CHENG, Spencer; MOURA, Eduardo G. de
  • conferenceObject
    ROLE OF MICRORNAS IN REGULATING TISSUE INFLAMMATION IN PATIENTS WITH BENIGN PROSTATIC HYPERPLASIA: PRELIMINARY RESULTS
    (2013) OLIVEIRA, Fabio; SAGAE, Vitor; REIS, Sabrina T.; VIANA, Nayara I.; LEITE, Katia R.; SROUGI, Miguel; ANTUNES, Alberto A.
  • article 0 Citação(ões) na Scopus
    Endoscopic stag beetle knife treatment for symptomatic Zenker's diverticulum
    (2021) MONTE, Epifanio Silvino do; IDE, Edson; SAGAE, Vitor Massaro Takamatsu; RIBEIRO, Igor Braga; FUNARI, Mateus Pereira; OLIVEIRA, Pedro Victor Aniz Gomes de; MOURA, Eduardo Guimaraes Hourneaux de
  • article 19 Citação(ões) na Scopus
    Gastrointestinal Manifestations and Associated Health Outcomes of COVID-19: A Brazilian Experience From the Largest South American Public Hospital
    (2020) MOURA, Diogo Turiani Hourneaux de; PROENCA, Igor Mendonca; MCCARTY, Thomas R.; SAGAE, Vitor Massaro Takamatsu; RIBEIRO, Igor Braga; OLIVEIRA, Guilherme Henrique Peixoto de; SOUZA, Gabriel Mayo Vieira de; HIRSCH, Bruno Salomao; SCATIMBURGO, Maria Vitoria Cury Vieira; THOMPSON, Christopher C.; CARRILHO, Flair Jose; CECCONELLO, Ivan; MOURA, Eduardo Guimaraes Hourneaux de
    OBJECTIVES: Brazil has rapidly developed the second-highest number of COVID-19 cases in the world. As such, proper symptom identification, including gastrointestinal manifestations, and relationship to health outcomes remains key. We aimed to assess the prevalence and impact of gastrointestinal symptoms associated with COVID-19 in a large quaternary referral center in South America. METHODS: This was a single-center cohort study in a COVID-19 specific hospital in Sao Paulo, Brazil. Consecutive adult patients with laboratory confirmed SARS-CoV-2 were included. Baseline patient history, presenting symptoms, laboratory results, and clinically relevant outcomes were recorded. Regression analyses were performed to determine significant predictors of the gastrointestinal manifestations of COVID-19 and hospitalization outcomes. RESULTS: Four-hundred patients with COVID-19 were included. Of these, 33.25% of patients reported gastrointestinal symptom. Diarrhea was the most common gastrointestinal symptom (17.25%). Patients with gastrointestinal symptoms had higher rates of concomitant constitutional symptoms, notably fatigue and myalgia (p <0.05). Gastrointestinal symptoms were also more prevalent among patients on chronic immunosuppressants, ACE/ARB medications, and patient with chronic kidney disease (p <0.05). Laboratory results, length of hospitalization, ICU admission, ICU length of stay, need for mechanical ventilation, vasopressor support, and in-hospital mortality did not differ based upon gastrointestinal symptoms (p> 0.05). Regression analyses showed older age [OR 1.04 (95% CI, 1.02-1.06)], male gender [OR 1.94 (95% CI, 1.12-3.36)], and immunosuppression [OR 2.60 (95% CI, 1.20-5.63)], were associated with increased mortality. CONCLUSION: Based upon this Brazilian study, gastrointestinal manifestations of COVID-19 are common but do not appear to impact clinically relevant hospitalization outcomes including the need for ICU admission, mechanical ventilation, or mortality.
  • conferenceObject
    ADVERSE EVENTS ASSOCIATED WITH DIFFERENT MODES OF ELECTRICAL CURRENT USED IN BILIARY SPHINCTEROTOMY: SYSTEMATIC REVIEW AND META-ANALYSIS OF RANDOMIZED CONTROLLED TRIALS
    (2019) FUNARI, Mateus P.; BERNARDO, Wanderlei M.; GALETTI, Facundo; SAGAE, Vitor M.; LOGIUDICE, Fernanda P.; MATSUBAYASHI, Carolina O.; BRUNALDI, Vitor O.; IDE, Edson; MOURA, Diogo T. de; MOURA, Eduardo G. de