JESSICA NATULINE IANOF

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LIM/45 - Laboratório de Fisiopatologia Neurocirúrgica, Hospital das Clínicas, Faculdade de Medicina

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  • article 47 Citação(ões) na Scopus
    Traumatic brain injury: An EEG point of view
    (2017) IANOF, Jéssica Natuline; ANGHINAH, Renato
    ABSTRACT Traumatic brain injury (TBI) is a silent epidemic. Mild traumatic brain injury (mTBI) causes brain injury that results in electrophysiologic abnormalities visible on electroencephalography (EEG) recordings. The purpose of this brief review was to discuss the importance of EEG findings in traumatic brain injury. Relevant articles published during the 1996-2016 period were retrieved from Medline (PubMed). The keywords were in English and included ""traumatic brain injury"", ""EEG"" and ""quantitative EEG"". We found 460 articles, analyzed 52 and selected 13 articles. EEG after TBI shows slowing of the posterior dominant rhythm and increased diffuse theta slowing, which may revert to normal within hours or may clear more slowly over many weeks. There are no clear EEG or quantitative EEG (qEEG) features unique to mild traumatic brain injury. Although the literature indicates the promise of qEEG in reaching a diagnosis and indicating prognosis of mTBI, further study is needed to corroborate and refine these methods.
  • article 11 Citação(ões) na Scopus
    Comparative analysis of the electroencephalogram in patients with Alzheimer's disease, diffuse axonal injury patients and healthy controls using LORETA analysis
    (2017) IANOF, Jéssica Natuline; FRAGA, Francisco José; FERREIRA, Leonardo Alves; RAMOS, Renato Teodoro; DEMARIO, José Luiz Carlos; BARATHO, Regina; BASILE, Luís Fernando Hindi; NITRINI, Ricardo; ANGHINAH, Renato
    ABSTRACT Alzheimer's disease (AD) is a dementia that affects a large contingent of the elderly population characterized by the presence of neurofibrillary tangles and senile plaques. Traumatic brain injury (TBI) is a non-degenerative injury caused by an external mechanical force. One of the main causes of TBI is diffuse axonal injury (DAI), promoted by acceleration-deceleration mechanisms. Objective: To understand the electroencephalographic differences in functional mechanisms between AD and DAI groups. Methods: The study included 20 subjects with AD, 19 with DAI and 17 healthy adults submitted to high resolution EEG with 128 channels. Cortical sources of EEG rhythms were estimated by exact low-resolution electromagnetic tomography (eLORETA) analysis. Results: The eLORETA analysis showed that, in comparison to the control (CTL) group, the AD group had increased theta activity in the parietal and frontal lobes and decreased alpha 2 activity in the parietal, frontal, limbic and occipital lobes. In comparison to the CTL group, the DAI group had increased theta activity in the limbic, occipital sublobar and temporal areas. Conclusion: The results suggest that individuals with AD and DAI have impairment of electrical activity in areas important for memory and learning.
  • conferenceObject
    Preliminary data of the first post-traumatic brain-injured (TBI) cognitive rehabilitation outpatient centre in Brazil (University of Sao Paulo, School of Medicine)
    (2017) AREZA-FEGYVERES, Renata; IANOF, Jessica Natuline; GUARIGLIA, Carla; WATANABE, Rafael Gustavo Sato; SCHMIDT, Magali Taino; FREIRE, Fabio Rios; NADRUZ, Patricia; OLIVEIRA, Eduardo; NASCIMENTO, Diana; ARAUJO, Amanda Vitoria; COELHO, Fernanda; ANGHINAH, Renato