MELISSA DE ALMEIDA RODRIGUES MACHADO

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  • article 49 Citação(ões) na Scopus
    Performance of an adult Brazilian sample on the Trail Making Test and Stroop Test
    (2014) CAMPANHOLO, Kenia Repiso; ROMÃO, Marcos Antunes; MACHADO, Melissa de Almeida Rodrigues; SERRAO, Valéria Trunkl; COUTINHO, Denise Gonçalves Cunha; BENUTE, Gláucia Rosana Guerra; LUCIA, Mara Cristina Souza de
    ABSTRACT Objective: The Trail Making Test (TMT) and Stroop Test (ST) are attention tests widely used in clinical practice and research. The aim of this study was to provide normative data for the adult Brazilian population and to study the influence of gender, age and education on the TMT parts A and B, and ST cards A, B and C. Methods: We recruited 1447 healthy subjects aged ≥18 years with an educational level of 0-25 years who were native speakers of Portuguese (Brazilian). The subjects were evaluated by the Matrix Reasoning and Vocabulary subtests of the Wechsler Adult Intelligence Scale-III, along with the TMTA, TMTB and ST A, B and C. Results: Among the participants, mean intellectual efficiency was 103.20 (SD: 12.0), age 41.0 (SD: 16.4) years and education 11.9 (SD: 5.6) years. There were significant differences between genders on the TMTA (p=0.002), TMTB (p=0.017) and STC (p=0.024). Age showed a positive correlation with all attention tests, whereas education showed a negative correlation. Gender was not found to be significant on the multiple linear regression model, but age and education maintained their interference. Conclusion: Gender did not have the major impact on attentional tasks observed for age and education, both of which should be considered in the stratification of normative samples.
  • article 46 Citação(ões) na Scopus
    Cognitive impairments in patients with low grade gliomas and high grade gliomas
    (2011) MIOTTO, Eliane C.; SILVA JUNIOR, Aluizio; SILVA, Clemar Correa; CABRERA, Hector Navarro; MACHADO, Melissa A. R.; BENUTE, Glaucia R. G.; LUCIA, Mara C. S.; SCAFF, Milberto; TEIXEIRA, Manoel Jacobsen
    Objective: The relationship between brain tumors and cognitive deficits is well established in the literature. However, studies investigating the cognitive status in low and high-grade gliomas patients are scarce, particularly in patients with average or lower educational level. This study aimed at investigating the cognitive functioning in a sample of patients with low and high-grade gliomas before surgical intervention. Method: The low-grade (G1, n=19) and high-grade glioma (G2, n=8) patients underwent a detailed neuropsychological assessment of memory, executive functions, visuo-perceptive and visuo-spatial abilities, intellectual level and language. Results: There was a significant impairment on verbal and visual episodic memory, executive functions including mental flexibility, nominal and categorical verbal fluency and speed of information processing in G2. G1 showed only specific deficits on verbal and visual memory recall, mental flexibility and processing speed. Conclusion: These findings demonstrated different levels of impairments in the executive and memory domains in patients with low and high grade gliomas.