ANA CLAUDIA GRIZZO PERES MARTINS
Índice h a partir de 2011
3
Projetos de Pesquisa
Unidades Organizacionais
Instituto Central, Hospital das Clínicas, Faculdade de Medicina
4 resultados
Resultados de Busca
Agora exibindo 1 - 4 de 4
- Extraordinary Findings in a Case of Self-inflicted Cutaneous Lesions(2017) CANUTO, Maria Julia; MARTINS, Ana Claudia Grizzo Peres; DWAN, Alexandre Jack; NETO, Cyro Festa; NICO, Marcello Menta Simonsen
- Delusional infestation: a case series from a university dermatology center in SAo Paulo, Brazil(2016) MARTINS, Ana Claudia G. P.; MENDES, Carolina P.; NICO, Marcello M. S.BackgroundMonosymptomatic hypochondriac psychosis (MHP) patients present with a delusional ideation that revolves around one particular hypochondriac concern. Delusional infestation is the most common type of MHP seen by the dermatologist. ObjectivesThis study was designed to retrospectively investigate a group of patients with delusions of infestation seen in an academic medical center in SAo Paulo, Brazil. MethodsA retrospective study of patients presenting with delusional infestation between 2007 and 2014 was conducted. Records were reviewed to study personal data, symptoms, and treatments. ResultsThirty patients were studied (22 female, eight male). Their mean age was 58 years in men and 60 years in women. Twenty-four patients spent most of their time at home (i.e. they were housewives, retired, or unemployed). The duration of disease varied from 3 months to 20 years. Fifteen patients brought in fragments of material that they believed to be parasites (specimen sign). Treatment consisted of the antipsychotic drugs pimozide (1-6 mg/d) or olanzapine (5-10 mg/d). Three patients did not return for follow-up. Follow-up varying from 2 months to 7 years was recorded in 24 patients. Two patients were treated with other psychoactive drugs prescribed by psychiatrists for additional psychiatric diagnoses. Control of symptoms was achieved in the majority of patients who underwent adequate follow-up. ConclusionsDelusional infestation is an extremely chronic disease. Attempts to discontinue treatment in those patients in whom a lengthy follow-up was performed inevitably resulted in symptom relapses.
- American tegumentary leishmaniasis: correlations among immunological, histopathological and clinical parameters(2014) MARTINS, Ana Luiza Grizzo Peres; BARRETO, Jaison Antonio; LAURIS, Jose Roberto Pereira; MARTINS, Ana Claudia Grizzo PeresBACKGROUND: American tegumentary leishmaniasis has an annual incidence of 1 to 1.5 million cases. In some cases, the patient's immune response can eliminate the parasite, and the lesion spontaneously resolves. However, when this does not occur, patients develop the disseminated form of the disease. OBJECTIVE: To investigate the association between clinical, laboratory and pathological findings in cases of American tegumentary leishmaniasis. METHODS: A retrospective study of the medical records of 47 patients with American cutaneous leishmaniasis. Clinical, laboratory and epidemiological data were collected, and semi-quantitative histopathological analyses were performed using the Spearman correlation coefficient (p <0.05). RESULTS: Mean patient age was 40.5 years. A total of 29.7% individuals were female and 70.2% were male, and 40.4% of the patients were farmers. The ulcerative form was found in 53.2% of patients, of whom 59.6% had lesions in the limbs. The average time to diagnosis was 22.3 months. The following positive correlations were significant: age and duration of the disease, Montenegro reaction, degree of granulomatous transformation and epithelioid cell count; duration of disease, Montenegro reaction and number of lymphocytes; epithelial hyperplasia and edema, hemorrhaging, and epithelial aggression; number of plasmocytes and number of parasites. The main negative correlations found were as follows: age and serology; time and parasite load; epithelial hyperplasia and degree of granulomatous transformation. CONCLUSION: The long duration of the disease could be explained by the fact that lesions were relatively asymptomatic, and therefore ignored by patients with low literacy levels. Individuals may have simply waited for spontaneous healing, which proved to be dependent on the activation of hypersensitivity mechanisms.
- Propylthiouracil-Induced Vasculitis With Antineutrophil Cytoplasmic Antibody(2015) CRIADO, Paulo Ricardo; MARTINS, Ana Claudia Grizzo Peres; GAVIOLLI, Camila Fatima; ALAVI, AfsanehPropylthiouracil (PTU)-associated vasculitis is a potentially life-threatening disease with a recent increase in the reported cases in the medical literature. This increase may suggest that some earlier cases have been unrecognized or assigned to an alternative nosology category. Although the skin can be the only organ affected by PTU-associated vasculitis, there are many reports with multiple-system involvement. Classically, the symptoms appear under a tetrad of fever, sore throat, arthralgia, and skin lesions. Cutaneous lesions in reported cases of PTU vasculitis have most commonly consisted of retiform acral, purpuric plaques, or nodules. We report a case of perinuclear antineutrophil cytoplasmic antibody-associated vasculitis developed during treatment with PTU for Grave's disease.