ERIQUE JOSE PEIXOTO DE MIRANDA

(Fonte: Lattes)
Índice h a partir de 2011
11
Lattes
ORCID
Projetos de Pesquisa
Unidades Organizacionais
SCPACEX-62, Hospital Universitário
LIM/20 - Laboratório de Terapêutica Experimental, Hospital das Clínicas, Faculdade de Medicina

Filtros

Limpar filtros

Configurações

Resultados de Busca

Agora exibindo 1 - 10 de 22
  • article 19 Citação(ões) na Scopus
    HIGH PREVALENCE OF THE SIMULTANEOUS EXCRETION OF POLYOMAVIRUSES JC AND BK IN THE URINE OF HIV-INFECTED PATIENTS WITHOUT NEUROLOGICAL SYMPTOMS IN SAO PAULO, BRAZIL
    (2012) NALI, Luiz Henrique da Silva; CENTRONE, Cristiane de Campos; URBANO, Paulo Roberto Palma; PENALVA-DE-OLIVEIRA, Augusto Cesar; VIDAL, Jose Ernesto; MIRANDA, Erique Peixoto; PANNUTI, Claudio Sergio; FINK, Maria Cristina Domingues da Silva
    Objective: To evaluate the prevalence of the urinary excretion of BKV and JCV in HIV-infected patients without neurological symptoms. Methods: Urine samples from HIV-infected patients without neurological symptoms were tested for JC virus and BK virus by PCR. Samples were screened for the presence of polyomavirus with sets of primers complementary to the early region of JCV and BKV genome (AgT). The presence of JC virus or BK virus were confirmed by two other PCR assays using sets of primers complementary to the VP1 gene of each virus. Analysis of the data was performed by the Kruskal-Wallis test for numerical data and Pearson or Yates for categorical variables. Results: A total of 75 patients were included in the study. The overall prevalence of polyomavirus DNA urinary shedding was 67/75 (89.3%). Only BKV DNA was detected in 14/75 (18.7%) urine samples, and only JCV DNA was detected in 11/75 (14.7%) samples. Both BKV and JCV DNA were present in 42/75 (56.0%) samples. Conclusion: In this study we found high rates of excretion of JCV, BKV, and simultaneous excretion in HIV+ patients. Also these results differ from the others available on the literature.
  • article 4 Citação(ões) na Scopus
    The long-term impact of a program to prevent central line-associated bloodstream infections in a surgical intensive care unit
    (2012) PAULA, Adriana P.; OLIVEIRA, Priscila R.; MIRANDA, Erique P.; FELIX, Cassia S.; LORIGADOS, Clara B.; GIOVANI, Arlete M.; LIMA, Ana Lucia L.
  • conferenceObject
    The Relationship Between Thyroid-Stimulating Hormone Levels and Lipoprotein Subfractions in the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil)
    (2018) PEIXOTO-MIRANDA, Erique J.; GOULART, Alessandra C.; BITTENCOURT, Marcio S.; BLAHA, Michael; JONES, Steven; SANTOS, Itamar S.; TOTH, Peter; KULKARNI, Krishnaji; LOTUFO, Paulo A.; BENSENOR, Isabela M.
  • bookPart
    Infecções associadas a cateteres e invasões
    (2017) MIRANDA, Erique José Peixoto de
  • article 0 Citação(ões) na Scopus
    Erratum in «High rate of virologic supression with darunavir/ritonavir plus optimazed background therapy among highly antiretroviral-experienced HIV-infected patients: results of a prospective cohort study in São Paulo, Brazil»
    (2013) VIDAL, José Ernesto; SONG, Alice Tung Wan; MATOS, Maria Laura; BARTMANN, Daniel; ANJOS, Guilherme dos; MIRANDA, Érique José Peixoto de; FREITAS, Ângela Carvalho; DALBEN, Mirian de Freitas; SANTANA, Claudinei; SEGURADO, Aluísio Cotrim; BARRETO, Cláudia Cortese; HERNÁNDEZ, Adrián Vladimir
  • conferenceObject
    Thyroid-stimulating Hormone Levels and Coronary Artery Calcium Score. The Brazilian Longitudinal Study of Adult Health (ELSA-Brasil)
    (2017) PEIXOTO-MIRANDA, Erique J.; BITTENCOURT, Marcio S.; STANIAK, Henrique L.; PEREIRA, Alexandre C.; FOPPA, Murilo; SANTOS, Itamar S.; LOTUFO, Paulo A.; BENSENOR, Isabela M.
  • article 27 Citação(ões) na Scopus
    Thyrotropin Levels, Insulin Resistance, and Metabolic Syndrome: A Cross-Sectional Analysis in the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil)
    (2015) BENSENOR, Isabela M.; GOULART, Alessandra Carvalho; MOLINA, Maria del Carmen B.; MIRANDA, Erique Jose Peixoto de; SANTOS, Itamar S.; LOTUFO, Paulo A.
    Background: Previous studies have described an association with thyrotropin (TSH) levels, insulin resistance, and metabolic syndrome. We performed a cross-sectional analysis to investigate the relationship between TSH levels, insulin resistance, and metabolic syndrome using baseline data from the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil). Methods: Diabetics and individuals using medications that interfere in thyroid function were excluded, leaving 10,935 participants (54.3% women) for current analyses. Homeostasis Model Assessment of Insulin Resistance (HOMA-IR) values above the 75th percentile was considered as indicative of presence of insulin resistance. Logistic regression models were built using HOMA-IR and metabolic syndrome as the dependent variable, and quintiles of TSH as the independent variable (first quintile as reference). Odds ratios (OR) were presented with multivariate adjustment for socioeconomic/cardiovascular risk factors for insulin resistance, and adjustment only for socioeconomic factors and smoking for metabolic syndrome. Results: Age, body mass index, waist measurement, fasting glucose and fasting and post load insulin and HOMA-IR increased according to TSH quintiles. Subjects in the fifth TSH quintile presented an OR of association with insulin resistance of 1.86 [95% confidence interval (95% CI) 1.26-2.75], regardless of gender. For the metabolic syndrome, subjects in the fifth quintile presented an OR of 1.21 (95% CI 1.01-1.45) and remained positive only for men (OR 1.37; 95% CI 1.07-1.76). Restricting the analysis to quintiles of TSH in the normal range did not change the results. Conclusions: In this cross-sectional evaluation, high TSH quintiles were associated to insulin resistance/metabolic syndrome.
  • article 12 Citação(ões) na Scopus
    Lack of Association Between Subclinical Hypothyroidism and Carotid-Femoral Pulse Wave Velocity in a Cross-Sectional Analysis of the ELSA-Brasil
    (2017) MIRANDA, Erique Jose F. Peixoto de; BITTENCOURT, Marcio Sommer; GOULART, Alessandra Carvalho; SANTOS, Itamar Souza; MILL, Jose Geraldo; SCHMIDT, Maria Ines; LOTUFO, Paulo Andrade; BENSENOR, Isabela J. Martins
    BACKGROUND There is little available data on carotid-femoral pulse wave velocity (cf-PWV) in subjects with subclinical hypothyroidism (SCH). We aimed to analyze the association between SCH and cf-PWV using baseline data from the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil). METHODS We included subjects with normal thyroid function (thyrotropin (TSH): 0.4-4.0 mIU/l, and normal free thyroxine (FT4: 0.8-1.9ng/dl) and SCH (TSH > 4.0 mIU/l and normal FT4) evaluated for cf-PWV in a crosssectional analysis. We excluded individuals using medications that interfere in thyroid function, antihypertensives, or diuretics, and subjects with chronic kidney disease or previous cardiovascular disease. Generalized linear and logistic regression models evaluated cf-PWV as a dependent variable and SCH as an independent variable, adjusted for cardiovascular risk factors. RESULTS Of 8,341 subjects (52.3% women), 7,878 (94.4%) were euthyroid and 463 (5.6%) showed SCH. The median age was 50 years (interquartile range: 44-56). The groups differed by age, sex, body mass index, glomerular filtration rate, and C-reactive protein. SCH was not associated with cf-PWV in the full-adjusted linear model (beta = -0.039; P = 0.562) and with cf-PWV > 75th percentile in the full-adjusted logistic model (odds ratio = 0.94; 95% confidence interval = 0.72-1.22). CONCLUSION In a large sample, SCH was not associated with increased cf-PWV.
  • article 15 Citação(ões) na Scopus
    Thyrotropin levels are associated with chronic kidney disease among healthy subjects in cross-sectional analysis of the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil)
    (2017) MIRANDA, Erique Jose F. Peixoto de; BITTENCOURT, Marcio Sommer; GOULART, Alessandra C.; SANTOS, Itamar S.; TITAN, Silvia Maria de Oliveira; LADEIRA, Roberto Marini; BARRETO, Sandhi Maria; LOTUFO, Paulo A.; BENSENOR, Isabela Judith Martins
    Few studies have evaluated a possible relationship between thyrotropin levels and glomerular filtration rate (GFR) and albumin/creatinine ratio in euthyroid subjects. We aimed to analyze this association using baseline data from the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil). Cross-sectionally, we included subjects with normal thyroid function and with subclinical hypothyroidism (SCH). We excluded individuals using medications that affect thyroid function. Linear and logistic regression models evaluated GFR estimated by Chronic Kidney Disease Epidemiology Collaboration (CKD-Epi) and albuminuria/creatinine ratio as dependent variables and thyrotropin quartiles in individuals with euthyroidism and SCH as independent variables, adjusted for demographical characteristics and diseases related to CKD. We included 13,193 subjects with a median age of 51 years [interquartile range, (IQR): 45-58], 6840 (51.8%) women, 12,416 (94.1%) euthyroid, and 777 (5.9%) with SCH. SCH subjects were characterized by higher age, triglycerides, frequency of white race, cardiovascular disease, CKD, and former smokers. In adjusted models, log-transformed TSH in euthyroid subjects was inversely and strongly associated with CKD (beta = -2.181, 95% CI -2.714 to -1.648), P < 0.0001 for glomerular filtration rate and 4.528 (1.190-7.865) for albuminuria/creatinine ratio. Multivariate logistic models for euthyroid subjects showed an OR of 1.45 (95% CI 1.15-1.83) for GFR and of 1.95 (95% CI 1.08-3.54) for albuminuria/creatinine ratio in the fourth quartile of TSH using the first as the reference. Thyrotropin levels are independently associated with CKD in euthyroid subjects.
  • article 28 Citação(ões) na Scopus
    Role of quantitative CSF microscopy to predict culture status and outcome in HIV-associated cryptococcal meningitis in a Brazilian cohort
    (2012) VIDAL, Jose E.; GERHARDT, Juliana; MIRANDA, Erique J. Peixoto de; DAUAR, Rafi F.; OLIVEIRA FILHO, Gilberto S.; OLIVEIRA, Augusto C. Penalva de; BOULWARE, David R.
    This retrospective study aimed to evaluate the clinical, laboratory, and quantitative cerebrospinal fluid (CSF) cryptococcal cell counts for associations with in-hospital outcomes of HIV-infected patients with cryptococcal meningitis. Ninety-eight HIV-infected adult patients with CSF culture-proven cryptococcal meningitis were admitted between January 2006 and June 2008 at a referral center in Sao Paulo, Brazil. Cryptococcal meningitis was the first AIDS-defining illness in 69%, of whom 97% (95/98) had known prior HIV infection. The median CD4+ T-cell count was 39 cells/mu L (interquartile range 17-87 cells/mu L). Prior antiretroviral therapy was reported in 50%. Failure to sterilize the CSF by 7-14 days was associated with baseline fungal burden of >= 10 yeasts/mu L by quantitative CSF microscopy (odds ratio [OR] = 15.3, 95% confidence interval [CI] 4.1-56.7; P < 0.001) and positive blood cultures (OR = 11.5,95% CI 1.2-109; P = 0.034). At 7-14 days, 10 yeasts/mu L CSF was associated with positive CSF cultures in 98% versus 36% with <10 yeasts/mu L CSF (P < 0.001). In-hospital mortality was 30% and was associated with symptoms duration for >14 days, altered mental status (P< 0.001), CSF white blood cell counts <5 cells/mu L (P = 0.027), intracranial hypertension (P = 0.011), viral loads >50,000 copies/mL (P = 0.036), >= 10 yeasts/mu L CSF at 7-14 days (P = 0.038), and intracranial pressure >50 cmH(2)O at 7-14 days (P = 0.007). In conclusion, most patients were aware of their HIV status. Fungal burden of >= 10 yeasts/mu L by quantitative CSF microscopy predicted current CSF culture status and may be useful to customize the induction therapy. High uncontrolled intracranial pressure was associated with mortality.