LUIZ ROBERTO COMERLATTI

Índice h a partir de 2011
3
Projetos de Pesquisa
Unidades Organizacionais
Instituto Central, Hospital das Clínicas, Faculdade de Medicina

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Agora exibindo 1 - 3 de 3
  • article 0 Citação(ões) na Scopus
    Risk factors independently associated with the maintenance of severe restriction of oral intake and alternative feeding method indication at hospital outcome in patients after acute ischemic stroke
    (2023) LEITE, Karoline Kussik de Almeida; SASSI, Fernanda Chiarion; PERISSINOTTI, Iago Navas; COMERLATTI, Luiz Roberto; ANDRADE, Claudia Regina Furquim de
    Background and aims: From a clinical point of view, post-stroke patients present difficulties in swallowing management. The purpose of this research was to identify risk factors that were independently related to the maintenance of a severe restriction of oral intake in patients affected by acute ischemic stroke.Methods: The authors conducted a prospective observational cohort study of patients with dysphagia post-acute ischemic stroke who were admitted to an Emergency Room (ER). Demographic and clinical data were collected at ER admission. Swallowing data was based on The Functional Oral Intake Scale (FOIS) and was collected at two distinct moments: initial swallowing assessment and at the patient outcome. Patients were divided into two groups according to their FOIS level assigned on the last swallowing assessment (at hospital outcome): G1 with severe restriction of oral intake and indication of feeding tube - patients with FOIS levels 1 to 4; G2 without restriction of food consistencies in oral intake - patients with FOIS levels 5 to 7.Results: One hundred and six patients were included in our study. Results of the multivariate logistic regression model for the prediction of maintenance of a severe restriction of oral intake at hospital outcome in patients post acute ischemic stroke indicated that increasing age (p = 0.006), and dysarthria (p = 0.003) were associated with higher chances of presenting severe restriction of oral intake at hospital outcome.Conclusions: Patients with acute ischemic stroke in an Emergency Room may experience non-resolved severe dysphagia, indicating the need to prepare for the care/rehabilitation of these patients.
  • article 0 Citação(ões) na Scopus
    Outcomes of acute basilar artery occlusion-real-world experience in a middle-income country
    (2022) GUERRA, Felipe Borelli Del; SILVA, Guilherme Diogo; PERISSINOTI, Iago Navas; MORAIS, Livia; MARSOLLA, Felipe Lorenzo Dornelas; COMERLATTI, Luiz Roberto; PUGLIA JUNIOR, Paulo; CONFORTO, Adriana Bastos
    Objectives Our goal was to describe outcomes in a single-center, real-world series of patients with acute basilar artery occlusion in a middle-income country. In addition, we assessed potential outcome predictors. Material and Methods Data from 28 patients were retrospectively reviewed. The primary outcome was death until last follow-up. Other outcomes were rates of favorable outcome until last follow-up and rates of intracranial hemorrhage. Outcomes were compared in subgroups according to several variables, including reperfusion (REP group) or no reperfusion (NOREP group) interventions, with chi-squared, Fisher's exact test, or Mann-Whitney tests. Results The rate of overall intrahospital death was 46%. Death until last follow-up occurred in 8/17 (47%) in the REP and in 7/11 (63%) of the NOREP group. Favorable outcomes were observed in 35.7% of the patients: 8/17 (47%) in REP and in 2/11 (18.1%) in NOREP. NIH stroke scale scores were significantly lower in patients with favorable outcomes. Intracranial hemorrhage was observed in 6/28 (21.4%) of the patients (all in REP group). Twenty patients were treated with anticoagulants within the first 24 h. No hemorrhage was observed in those treated with enoxaparin, while three occurred in subjects treated with unfractionated heparin. Conclusion Together with other series, our results underscore the relevance of NIH stroke scale at admission as a prognostic marker, the importance of reperfusion to improve outcomes, and the need of clinical trials to compare the impact of treatment with anticoagulants within first 24 h in basilar artery occlusion.
  • conferenceObject
    Topic: AS28 Stroke in Low- and Middle-Income Countries A SINGLE CENTER RETROSPECTIVE REALWORLD EXPERIENCE IN ACUTE BASILAR ARTERY OCCLUSION
    (2021) GUERRA, F. Del; SILVA, G.; PERISSINOTI, I.; MORAIS, L.; COMERLATTI, L.; JUNIOR, P.; CONFORTO, A.