JOELMA QUEIROZ ANDRADE

(Fonte: Lattes)
Índice h a partir de 2011
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Instituto Central, Hospital das Clínicas, Faculdade de Medicina - Médico
Instituto do Coração, Hospital das Clínicas, Faculdade de Medicina - Médico
LIM/57 - Laboratório de Fisiologia Obstétrica, Hospital das Clínicas, Faculdade de Medicina

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Autor e Coautores FMUSP-HC Normalizados: MARCELO ZUGAIB ×

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  • article 6 Citação(ões) na Scopus
    Molecular Epidemiology of Rubella Viruses Involved in Congenital Rubella Infections in Sao Paulo, Brazil, Between 1996 and 2009
    (2013) CURTI, Suely Pires; FIGUEIREDO, Cristina Adelaide; OLIVEIRA, Maria Isabel de; ANDRADE, Joelma Queiroz; ZUGAIB, Marcelo; YU, Ana Lucia Frugis; OLIVEIRA, Danielle Bruna; DURIGON, Edison Luiz
    Rubella virus (RV) infection during the early stages of pregnancy can lead to serious birth defects, known as congenital rubella syndrome (CRS). This retrospective study was conducted between 1996 and 2009 with surveillance specimens collected from patients suspected of congenital rubella infection (CRI) and CRS. The clinical samples (nine amminiotic fluid, eight urine, eight blood, one conception product, and one placenta) were sent for viral isolation and genotyping. Twenty-seven sequences were analysed and four genotypes (1a, 1B, 1G, and 2B) were identified in SAo Paulo that were involved in congenital infection. To our knowledge, this study is the first report that describes genetic diversity of the circulating rubella strains involved in CRI. J Med. Virol. 85:2034-2041, 2013. (c) 2013 Wiley Periodicals, Inc.
  • article 3 Citação(ões) na Scopus
    Isolation and Genotyping of Rubella Virus From a Case of Congenital Infection in Brazil
    (2011) ANDRADE, J. Q.; FIGUEIREDO, C. A.; OLIVEIRA, M. I.; CARVALHO, M. H. B.; SCHULTZ, R.; ZUGAIB, M.
    The incidence of CRS and CRI has decreased markedly worldwide with the implementation of efficient vaccination programs. We report a congenital rubella case with fetal death occurred at 29th week of gestation. RV was confirmed in placenta. The results of phylogenetic analysis showed that the RVs/Sao-Paulo01.- BRA/08.CRI belongs to the genotype 2B of RV. J. Med. Virol. 83:2048-2050, 2011. (C) 2011 Wiley-Liss, Inc.
  • article 3 Citação(ões) na Scopus
    Prenatal diagnosis of congenital rubella infection in Sao Paulo
    (2014) CURTI, Suely Pires; FIGUEIREDO, Cristina Adelaide; OLIVEIRA, Maria Isabel de; ANDRADE, Joelma Queiroz; ZUGAIB, Marcelo; PEDREIRA, Denise Araujo Lapa; DURIGON, Edison Luiz
    Objective: rubella during the early stages of pregnancy can lead to severe birth defects known as congenital rubella syndrome (CRS). Samples collected from pregnant women with symptoms and suspected of congenital rubella infection between 1996 and 2008 were analyzed. Methods: a total of 23 amniotic fluid samples, 16 fetal blood samples, 1 product of conception and 1 placenta were analyzed by serology and RT-PCR. Results: all patients presented positive serology for IgG / IgM antibodies to rubella virus. Among neonates, 16 were IgG-positive, 9 were IgM-positive and 4 were negative for both antibodies. Of the 25 samples analyzed in this study, 24 were positive by RT-PCR. Changes in ultrasound were found in 15 (60%) of 25 fetuses infected with rubella virus. Fetal death and miscarriage were reported in 10(40%) of the 25 cases analyzed. The rubella virus was amplified by PCR in all fetuses with abnormal ultrasound compatible with rubella. Fetal death and abortion were reported in 10 of 25 cases analyzed. Conclusion: this study, based on primary maternal rubella infection definitely confirms the good sensitivity and specificity of RT-PCR using amniotic fluid and ultrasound. The results showed that molecular assays are important tools in the early diagnosis of rubella and congenital rubella syndrome.