JAYR SCHMIDT FILHO
Índice h a partir de 2011
5
Projetos de Pesquisa
Unidades Organizacionais
Instituto do Câncer do Estado de São Paulo, Hospital das Clínicas, Faculdade de Medicina - Médico
8 resultados
Resultados de Busca
Agora exibindo 1 - 8 de 8
- Brazilian Nutritional Consensus in Hematopoietic Stem Cell Transplantation: Adults(2020) BARBAN, Juliana Bernardo; SIMOES, Belinda Pinto; MORAES, Bruna Del Guerra de Carvalho; ANUNCIACAO, Cassia Rehem da; ROCHA, Cristiane Santos da; PINTOR, Daniela Cristina Querino; GUERRA, Daiane Cristina; SILVA, Deise Andrade; BRANDAO, Edith de Castro Martins; KERBAUY, Fabio; PIRES, Fernanda Ramos de Oliveira; MORAIS, Graciele Lima; SCHMIDT FILHO, Jayr; SICCHIERI, Juliana Maria Faccioli; BARROSO, Karine Sampaio Nunes; VIANA, Luciana Vercoza; ROCHA, Mariana Hollanda Martins da; GUIMARAES, Maysa Penteado; LAZZARI, Natalia Leonetti Couto; HAMERSCHLAK, Nelson; RAMOS, Patricia; GOMES, Plinio Nascimento; MENDONCA, Priscila da Silva; OLIVEIRA, Raquel Candido de; SCOMPARIM, Renata Correa; CHIATTONE, Ricardo; DIEZ-GARCIA, Rosa Wanda; CARDENAS, Thais de Campos; MIOLA, Thais Manfrinato; COSTA, Thalita Cristina de Mello; ROCHA, Vanderson; PEREIRA, Andrea Z.The nutritional status of patients submitted to hematopoietic stem cell transplant is considered an independent risk factor, which may influence on quality of life and tolerance to the proposed treatment. The impairment of nutritional status during hematopoietic stem cell transplant occurs mainly due to the adverse effects resulting from conditioning to which the patient is subjected. Therefore, adequate nutritional evaluation and follow-up during hematopoietic stem cell transplant are essential. To emphasize the importance of nutritional status and body composition during treatment, as well as the main characteristics related to the nutritional assessment of the patient, the Brazilian Consensus on Nutrition in Hematopoietic Stem Cell Transplant: Adults was prepared, aiming to standardize and update Nutritional Therapy in this area. Dietitians, nutrition physicians and hematologists from 15 Brazilian centers thar are references in hematopoietic stem cell transplant took part.
conferenceObject Comparative Analysis of Conditioning Regimens in Patients Undergoing Autologous Hematopoietic STEM CELL Transplant for Lymphoma in a Single Brazilian Center(2019) SCHMIDT-FILHO, Jayr; RAYOL, Sergio; YAMAGUCHI, Marcela; ATANAZIO, Marcelo; MARIANO, Livia; ROSSETTI, Renata; ROCHA, Vanderson- Epidemiology, risk factors and outcomes of multi-drug-resistant bloodstream infections in haematopoietic stem cell transplant recipients: importance of previous gut colonization(2018) FERREIRA, A. M.; MOREIRA, F.; GUIMARAES, T.; SPADAO, F.; RAMOS, J. F.; BATISTA, M. V.; FILHO, J. S.; COSTA, S. F.; ROCHA, V.Background: Bloodstream infections (BSI) are a major complication in the early phase of a haematopoietic stem cell transplant (HSCT). Aim: To describe the incidence and risk factors for BSI occurring in the pre-engraftment phase of HSCT, and its impact on mortality. Methods: Clinical variables of 232 HSCT patients were analysed retrospectively between 2014 and 2015. Univariate Cox regression analyses were performed to test the association between each covariate and the outcome. Covariates with P < 0.10 on univariate analysis were included in a multiple Cox regression analysis using a backward elimination method. Findings: The cumulative incidence of BSI was 25.4%, mainly caused by Gram-negative bacteria (GNB) (55.2%). Approximately 40.5% of the patients had gut colonization by multi-drug-resistant (MDR) bacteria (vancomycin-resistant enterococcus and carbapenem-resistant GNB). Among patients colonized by MDR GNB, 20% developed an overt BSI due to MDR bacteria with the same pattern of sensitivity. Of the 13 deaths related to infection, 10 were patients with BSI caused by MDR GNB. The independent risk factors for BSI were gut colonization by MDR bacteria including GNB (P < 0.001) and duration of neutropenia >10 days (P = 0.005), and those associated with BSI caused by MDR bacteria were age >62 years (P = 0.03), use of total parenteral nutrition (TPN) (P < 0.001) and previous gut colonization by MDR GNB (P = 0.002). Conclusions: Previous gut colonization by MDR was an independent risk factor for BSI, together with TPN and age, and had an impact on outcome. These findings suggest that gut decolonization may be a potential strategy to prevent BSI.
conferenceObject Viral Reactivation after T-Cell Replete Haploidentical Transplantation Using Myeloablative Conditioning and Post-Transplant Cyclophosphamide(2016) BEZERRA, Evandro; SILVA, Roberto Luiz da; SCHMIDT FILHO, Jayr; SANTOS, Marina; NASCIMENTO, Marina; SIMOES, Aline; XAVIER, Erick; ALMEIDA, Manuella; MARIANO, Livia Caroline; FERNANDES, Pedro; MARQUES, Larissa; COSTA, Sylvia; SEBER, Adriana; MACEDO, Maria Cristina; MACHADO, Clarisse- Capnocytophaga sputigena bloodstream infection in hematopoietic stem cell transplantations: two cases report and review of the literature(2020) MENDES, Fernanda Rodrigues; BRUNIERA, Felipe Ribeiro; SCHMIDT, Jayir; CURY, Ana Paula; RIZECK, Camila; HIGASHINO, Hermes; OLIVEIRA, Fernando Nivaldo; ROSSI, Flavia; ROCHA, Vanderson; COSTA, Silvia FigueiredoCapnocytophaga is a group of facultative anaerobic gram-negative bacteria present in the oral cavity of humans, dogs and cats, as part of their normal oral flora. Here, we described two cases of bloodstream infections (BSI) caused by Capnocytophaga in neutropenic autologous hematopoietic stem cell transplantation (auto-HSCT) patients with mucositis (Grade I and Grade III) identified by Maldi-Tof. They were successfully treated with beta-lactam (meropenem and piperacillin-tazobactam). The species C. sputigena was confirmed by 16S rRNA gene sequencing in one patient. The review of literature showed that C. ochraceae was the most frequent species causing BSI in auto-HSCT patients and that the patients usually presented mucositis and were neutropenic at the onset of the infection.
- Cryopreserved versus non-cryopreserved peripheral blood stem cells for autologous transplantation after high-dose Melphalan in multiple myeloma: comparative analysis(2019) BITTENCOURT, M. C. B.; MARIANO, L.; MOREIRA, F.; SCHMIDT-FILHO, J.; MENDRONE- JR., A.; ROCHA, V.
- A case-series of Toxoplasmosis in hematopoietic stem cell transplantation: still a concern for endemic countries(2018) PRESTES, Daniel P.; MENDES, Clara; BATISTA, Marjorie V.; RAMOS, Jessica F.; SCHIMIDT JUNIOR, Jayr; OKAY, Thelma Suely; CAIAFFA, Helio; ROCHA, Vanderson G.; COSTA, Silvia Figueiredo
- Disseminated Skin Lesions After Allogeneic Hematopietic Stem Cell Transplantation(2018) NEFFA, Pedro Pereira; SCHMIDT FILHO, Jayr; RAMOS, Jessica Fernandes; OKAY, Thelma Suely; CASTELLI, Jussara Bianchi; ROCHA, Vanderson; COSTA, Silvia Fiqueiredo; BATISTA, Marjorie Vieira