MARCELO VALENTE
Índice h a partir de 2011
2
Projetos de Pesquisa
Unidades Organizacionais
LIM/21 - Laboratório de Neuroimagem em Psiquiatria, Hospital das Clínicas, Faculdade de Medicina
5 resultados
Resultados de Busca
Agora exibindo 1 - 5 de 5
- Liver and spleen biometrics in childhood-onset systemic lupus erythematosus patients(2015) GUARIENTO, Andressa; SILVA, Marco Felipe C.; TASSETANO, Priscilla S. F.; ROCHA, Silvia Maria S.; CAMPOS, Lucia M. A.; VALENTE, Marcelo; SILVA, Clovis A.Objective: To evaluate liver and spleen dimensions in childhood-onset systemic lupus erythematosus (c-SLE) patients and healthy controls. Methods: 30 c-SLE patients and 30 healthy control volunteers underwent abdominal ultrasound. The following two liver measurements were performed in left hepatic lobe: craniocaudal and anteroposterior and three in right hepatic lobe (RHL): posterior craniocaudal (PCC-RHL), anterior craniocaudal and anteroposterior. Three spleen dimension measurements were also evaluated: longitudinal, transverse and anteroposterior. Demographic, clinical and laboratorial data, SLEDAI-2K, ECLAM, SLAM and treatment were assessed. Results: Mean current age was similar in c-SLE and controls (170.31 +/- 27.81 vs. 164.15 +/- 39.25 months; p = 0.486). The mean of PCC-RHL dimension was significantly higher in c-SLE compared to controls (13.30 +/- 1.85 vs. 12.52 +/- 0.93, p = 0.044). There were no differences between the other hepatic biometrics and splenic parameters (p > 0.05). Further analysis in c-SLE patients according to PCC-FtHL dimension >= 13.3 cm versus <13.3 cm showed that the median of SLEDAI-2K [8 (0-18) vs. 2 (0-8), p = 0.004], ECLAM 14 (0-9) vs. 2 (0-5), p = 0.0191 and SLAM [5 (1-13) vs. 2 (0-14), p = 0.016] were significantly higher in patients with higher PCC-RHL dimension, likewise the frequencie of nephritis (77% vs. 29%, p = 0.010). Liver enzymes were similar in both groups (p > 0.05). Positive correlation was observed between SLEDAI-2K and PCC-RHL (p = 0.001, r = +0.595). Negative correlation was evidenced between disease duration and longitudinal dimension of spleen (p = 0.031, r = -0.394). Conclusion: Our data raises the possibility that disease activity could lead to a subclinical and localized hepatomegaly during the disease course. Long disease duration resulted to spleen atrophy in c-SLE patients.
bookPart Considerações sobre a semiologia diagnóstica por imagem em endocrinologia pediátrica(2016) VALENTE, MarcelobookPart Diabetes mellitus(2023) VALENTE, Marcelo- Radiologia pediátrica: quando o diagnóstico deve ser ""amigo"" da criança(2012) VALENTE, Marcelo; OLIVEIRA, Luiz Antonio Nunes de; CARNEIRO-SAMPAIO, Magda
- Reopening the Debate on Radiation Exposure in the PICU(2013) PANCERA, Christiane; CARVALHO, Werther Brunow de; VALENTE, Marcelo; DELGADO, Artur Figueiredo