LAURA SILVEIRA MORIYAMA

Índice h a partir de 2011
3
Projetos de Pesquisa
Unidades Organizacionais

Filtros

Limpar filtros

Configurações

Assunto: Neurosciences ×

Resultados de Busca

Agora exibindo 1 - 2 de 2
  • article 3 Citação(ões) na Scopus
    The Hitchhiker's guide to the rhinencephalon
    (2016) SILVEIRA-MORIYAMA, Laura; GLASS, Philip; RAJAN, Suraj; CARVALHO, Rafael; REIS, Fabiano; PENATTI, Carlos A. A.; MUIO, Valeria
    Pathology of the rhinencephalon has been a subject of interest in the fields of neurodegenerative diseases, trauma, epilepsy and other neurological conditions. Most of what is known about the human rhinencephalon comes from comparative anatomy studies in other mammals and histological studies in primates. Functional imaging studies can provide new and important insight into the function of the rhinencephalon in humans but have limited spatial resolution, limiting its contribution to the study of the anatomy of the human rhinencephalon. In this study we aim to provide a brief and objective review of the anatomy of this important and often overlooked area of the nervous system.
  • article 9 Citação(ões) na Scopus
    Olfactory Function in SCA10
    (2019) MOSCOVICH, Mariana; MUNHOZ, Renato Puppi; MORO, Adriana; RASKIN, Salmo; MCFARLAND, Karen; ASHIZAWA, Tetsuo; TEIVE, Helio A. G.; SILVEIRA-MORIYAMA, Laura
    Although the main clinical manifestations of spinocerebellar ataxias (SCAs) result from damage of the cerebellum, other systems may also be involved. Olfactory deficits have been reported in other types of ataxias, especially in SCA3; however, there are no studies on olfactory deficits in SCA type 10 (SCA10). To analyze olfactory function of SCA10 patients compared with that of SCA3, Parkinson's, and healthy controls. Olfactory identification was tested in three groups of 30 patients (SCA10, SCA3, and Parkinson's disease (PD)) and 44 healthy controls using the Sniffin' Sticks (SS16) test. Mean SS16 score was 11.9 +/- 2.9 for the SCA10 group, 12.3 +/- 1.9 for the SCA3 group, 6.6 +/- 2.8 for the PD group, and 12.1 +/- 2.0 for the control group. Mean SS16 score for the SCA10 group was not significantly different from the scores for the SCA3 and control groups but was significantly higher than the score for the PD group (p<0.001) when adjusted for age, gender, and history of smoking. There was no association between SS16 scores and disease duration in the SCA10 or SCA3 groups or number of repeat expansions. SS16 and Mini Mental State Examination scores were correlated in the three groups: SCA10 group (r=0.59, p=0.001), SCA3 group (r=0.50, p=0.005), and control group (r=0.40, p=0.007). We found no significant olfactory deficits in SCA10 in this large series.