FABIO RAMALHO TAVARES MARINHO

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Instituto do Coração, Hospital das Clínicas, Faculdade de Medicina - Médico

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  • conferenceObject
    SEDATION IN DIGESTIVE ENDOSCOPY - PROPOFOL VERSUS TRADITIONAL SEDATIVE AGENTS: SYSTEMATIC REVIEW WITH META-ANALYSIS
    (2018) DELGADO, Aureo A.; BERNARDO, Wanderlei M.; COUTINHO, Lara M.; MARINHO, Fabio R.; LERA, Marcos; IDE, Edson; MOURA, Eduardo G. de
  • article 11 Citação(ões) na Scopus
    Papillary fistulotomy vs conventional cannulation for endoscopic biliary access: A prospective randomized trial
    (2018) FURUYA, Carlos Kiyoshi; SAKAI, Paulo; MARINHO, Fabio Ramalho Tavares; OTOCH, Jose Pinhata; CHENG, Spencer; PRUDENCIO, Livia Lemes; MOURA, Eduardo Guimaraes Hourneaux de; ARTIFON, Everson Luiz de Almeida
    AIM To compare the cannulation success, biochemical profile, and complications of the papillary fistulotomy technique vs catheter and guidewire standard access. METHODS From July 2010 to May 2017, patients were prospectively randomized into two groups: Cannulation with a catheter and guidewire (Group.) and papillary fistulotomy (Group.). Amylase, lipase and C-reactive protein at T0, as well as 12 h and 24 h after endoscopic retrograde cholangiopancreatography, and complications (pancreatitis, bleeding, perforation) were recorded. RESULTS We included 102 patients (66 females and 36 males, mean age 59.11 +/- 18.7 years). Group. and Group. had 51 patients each. The successful cannulation rates were 76.5% and 100%, respectively (P = 0.0002). Twelve patients (23.5%) in Group. had a difficult cannulation and underwent fistulotomy, which led to successful secondary biliary access (Failure Group). The complication rate was 13.7% (2 perforations and 5 mild pancreatitis) vs 2.0% (1 patient with perforation and pancreatitis) in Groups. and., respectively (P = 0.0597). CONCLUSION Papillary fistulotomy was more effective than guidewire cannulation, and it was associated with a lower profile of amylase and lipase. Complications were similar in both groups.
  • conferenceObject
    Systematic Review and Meta-Analysis of the Endoscopic Treatment for Weight Regain Following Roux-En-Y Gastric Bypass and the Role of Argon Plasma Coagulation Prior to Endoscopic Suture
    (2017) BRUNALDI, Vitor O.; BERNARDO, Wanderlei M.; OKAZAKI, Ossamu; MARINHO, Fabio R.; MOURA, Diogo T. de; RICCIOPPO, Daniel; SANTO, Marco Aurelio; GALVAO NETO, Manoel; MOURA, Eduardo G. de
  • bookPart
    Diagnóstico de Lesões Malignas do Pâncreas
    (2017) MARINHO, Fábio Ramalho Tavares; GUEDES, Hugo Gonçalo; MOURA, Eduardo Turiani Hourneaux de; CHENG, Spencer; SOUSA, Marcelo Magno de Freitas; CHAVES, Dalton Marques
  • article 16 Citação(ões) na Scopus
    Early Endoscopic Retrograde Cholangiopancreatography Versus Conservative Treatment in Patients With Acute Biliary Pancreatitis: Systematic Review and Meta-analysis of Randomized Controlled Trials
    (2018) COUTINHO, Lara M. de A.; BERNARDO, Wanderley M.; ROCHA, Rodrigo S.; MARINHO, Fabio R.; DELGADO, Aureo; MOURA, Eduardo T. H.; MATUGUMA, Sergio E.; CHAVES, Dalton; FRANZINI, Tomazo A. P.; SAKAI, Paulo; MOURA, Eduardo G. H. de
    Objectives The aim of the study was to evaluate the role of early endoscopic retrograde cholangiopancreatography (ERCP) in the treatment of acute biliary pancreatitis, in comparison with conservative treatment. Methods Systematic review via databases (MEDLINE [PubMed], Latin-American and Caribbean Health Sciences Literature database, Embase, Cochrane Central, and the [Brazilian] Regional Library of Medicine) is conducted. We analyzed 10 randomized controlled trials (1091 patients). Outcomes were the following: local and systemic adverse events; acute cholangitis; death; length of hospital stay; cost; abdominal pain; and time to a reduction in body temperature. For the meta-analysis, we used risk difference (RD) and mean with standard deviation as measures of variability. Results There was a statistically significant difference between the patients submitted to ERCP in terms of the following: local adverse events (RD, 0.74; 95% confidence interval [CI], 0.55-0.99), time to pain relief and time to a reduction in axillary temperature (RD, -5.01; 95% CI, -6.98 to -3.04, and RD, -1.70; 95 CI%, -2.33 to -1.08, respectively). Patients undergoing ERCP spent less time in hospital (RD, -11.04; 95% CI, -15.15 to -6.93). Cost was lower in the group treated with ERCP. Conclusions Early ERCP decreases local adverse events, shortening the time to pain relief, to a reduction in axillary temperature, hospital stays, and cost in patients with acute biliary pancreatitis.
  • conferenceObject
    COMPARISON BETWEEN ENDOSCOPIC SPHINCTEROTOMY VERSUS ENDOSCOPIC SPHINCTEROTOMY ASSOCIATED WITH BALLOON DILATION FOR REMOVAL OF BILE DUCT STONES: A SYSTEMATIC REVIEW AND META-ANALYSIS BASED ON RANDOMIZED CONTROLLED TRIALS.
    (2018) CLEMENTE JUNIOR, Cesar C. de; BERNARDO, Wanderlei M.; FRANZINI, Tomazo; LUZ, Gustavo O.; SANTOS, Marcos E. dos; MARINHO, Fabio R.; CORONEL, Martin A.; SAKAI, Paulo; MOURA, Eduardo G. de
  • conferenceObject
    The Role of Early Ercp in the Treatment of Acute Biliary Pancreatitis Compared to Conservative Treatment: Systematic Review and Meta-Analysis
    (2017) COUTINHO, Lara M.; ROCHA, Rodrigo S.; MATUGUMA, Sergio E.; MOURA, Eduardo T.; MOURA, Eduardo G. de; CHAVES, Dalton; MARINHO, Fabio R.; DELGADO, Aureo
  • conferenceObject
    CONVENTIONAL CANNULATION OR PAPILLARY FISTULOTOMY: A PROSPECTIVE RANDOMIZED TRIAL
    (2018) FURUYA, Carlos K.; MARINHO, Fabio R.; CHENG, Spencer; SAKAI, Paulo; ARTIFON, Everson L.
  • conferenceObject
    Hydrostatic Dilation of the Cardia for Achalasia: Technique and Results Using the Loss of the Radiological Waist As a Procedure Guidance Parameter. A Prospective Case Study
    (2017) MARINHO, Fabio R.; MOURA, Eduardo T.; COUTINHO, Lara M.; DELGADO, Aureo; ZORRON, Leonardo; CORONEL, Martin; MOURA, Diogo T. de; CHENG, Spencer; SALLUM, Rubens A.; SAKAI, Paulo; MOURA, Eduardo G. de
  • article
    Comparison between endoscopic sphincterotomy vs endoscopic sphincterotomy associated with balloon dilation for removal of bile duct stones: A systematic review and meta-analysis based on randomized controlled trials
    (2018) CLEMENTE JUNIOR, Cesar Capel de; BERNARDO, Wanderley Marques; FRANZINI, Tomazo Prince; LUZ, Gustavo Oliveira; SANTOS, Marcos Eduardo Lera dos; COHEN, Jonah Maxwell; MOURA, Diogo Turiani Hourneaux de; MARINHO, Fabio Ramalho Tavares; CORONEL, Martin; SAKAI, Paulo; MOURA, Eduardo Guimaraes Hourneaux de
    AIM To compare gallstones removal rate and incidence of bleeding, pancreatitis, use of mechanical lithotripsy, cholangitis and perforation between isolated sphincterotomy vs sphincterotomy associated with balloon dilation of papilla in choledocholithiasis through the meta-analysis of randomized clinical trials. METHODS We conducted a systematic review according to the PRISMA guidelines. Literature search was restricted to randomized controlled trials (RCTs) on MedLine, Cochrane Library, LILACS, and EMBASE database platforms in July 2017. The manual search included references of retrieved articles. We extracted data focusing on outcomes: The primary endpoint was the stones removal rate; Secondary endpoints were rates of pancreatitis, bleeding, use of mechanical lithotripsy (ML), perforation and cholangitis. RESULTS Eleven RCTs with 1824 patients were included. EST was associated with more post-endoscopic retrograde cholangiopancreatography (ERCP) bleeding [FE RD-0.02, CI (-0.03, -0.00), I-2 = 33%, P = 0.05] and more need of mechanical lithotripsy in general [RE RD-0.16, CI (-0.25, -0.06), I-2 = 90%, P = 0.002] and in subgroup analysis of stones greater than 15 mm [RE RD-0.20, CI (-0.38, -0.02), I-2 = 82%, P = 0.003]. Incidence of pancreatitis [FE RD-0.01, CI (-0.03, 0.01), I-2 = 0, P = 0.36], cholangitis [FE RD-0.00, CI (-0.01, 0.01), I-2 = 0, P = 0.97] and perforation [FE RD-0.01, CI (-0.01, 0.00), I-2 = 0, P = 0.23] was similar between the groups as well as similar stone removal rates in general [FE RD-0.01, CI (-0.01, 0.04), I-2 = 0, P = 0.23] and pooled analysis of stones greater than 15 mm [FE RD-0.02, CI (-0.02, 0.07), I-2 = 11%, P = 0.31]. CONCLUSION Through meta-analysis of randomized clinical trials we found that isolated sphincterotomy was associated with more post-ERCP bleeding and more need for mechanical lithotripsy. However, there was no statistical difference in the stone removal rate between isolated sphincterotomy and sphincterotomy associated with balloon dilation in the approach to remove gallstones.