Deep Endometriosis: the Involvement of Multiple Pelvic Compartments Is Associated with More Severe Pain Symptoms and Infertility

Página do item simplificado
dc.contributorSistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP
dc.contributor.authorROCHA, Taina Pezzin
dc.contributor.authorANDRES, Marina Paula
dc.contributor.authorCARMONA, Francisco
dc.contributor.authorBARACAT, Edmund Chada
dc.contributor.authorABRAO, Mauricio Simoes
dc.date.accessioned2023-06-21T14:12:13Z
dc.date.available2023-06-21T14:12:13Z
dc.date.issued2023
dc.description.abstractEndometriosis can be classified into three phenotypes: superficial, ovarian, and deep. Deep endometriosis (DE) has been associated with more severe pain symptoms, although no large-scale studies have evaluated the association between pain intensity and infertility and the different compartments of the pelvis affected by superficial and DE. This retrospective study included 1116 women who underwent laparoscopy for endometriosis treatment at two referral centers between 2009 and 2019. For the evaluation of each symptom, patients were divided according to their visual analog scale score (< 7 and >= 7) and fertility status. On multiple logistic regression, severe dysmenorrhea and dyschezia were correlated with DE of the posterior compartment alone (odds ratio (OR) = 1.6, confidence interval (CI) 1.09-2.34, and p = 0.02 and OR = 2.09, CI 1.36-3.23, and p < 0.01, respectively) and in combination with other compartments. DE of the posterior and lateral compartments had the most consistent statistical power (OR = 3.55 for dysmenorrhea and OR = 4.4 for dyschezia). Infertility was associated with DE of the posterior compartment alone (OR = 1.6, CI 1.06-2.54, p = 0.04) and in combination with the anterior compartment (OR = 2.62, CI 1.29-5.29, p < 0.01), with the combination of posterior and anterior compartment having the highest OR value. Severe dyschezia and infertility were also correlated with the presence of multiple localizations of DE (p = 0.04 and p < 0.01). This study confirms the association between DE and severe pain symptoms as well as the influence of the number of DE compartments on the severity of symptoms and the chance of infertility.eng
dc.description.indexMEDLINE
dc.description.indexPubMed
dc.description.indexWoS
dc.description.indexScopus
dc.identifier.citationREPRODUCTIVE SCIENCES, v.30, n.5, p.1668-1675, 2023
dc.identifier.doi10.1007/s43032-022-01104-9
dc.identifier.eissn1933-7205
dc.identifier.issn1933-7191
dc.identifier.urihttps://observatorio.fm.usp.br/handle/OPI/53976
dc.language.isoeng
dc.publisherSPRINGER HEIDELBERGeng
dc.relation.ispartofReproductive Sciences
dc.rightsrestrictedAccesseng
dc.rights.holderCopyright SPRINGER HEIDELBERGeng
dc.subjectDeep endometriosiseng
dc.subjectLocalizationeng
dc.subjectCompartmentseng
dc.subjectSymptomseng
dc.subjectInfertilityeng
dc.subject.othernerve growth-factoreng
dc.subject.otherinfiltrating endometriosiseng
dc.subject.otherwomeneng
dc.subject.otherperitonealeng
dc.subject.otherextenteng
dc.subject.otherstageeng
dc.subject.wosObstetrics & Gynecologyeng
dc.subject.wosReproductive Biologyeng
dc.titleDeep Endometriosis: the Involvement of Multiple Pelvic Compartments Is Associated with More Severe Pain Symptoms and Infertilityeng
dc.typearticleeng
dc.type.categoryoriginal articleeng
dc.type.versionpublishedVersioneng
dspace.entity.typePublication
hcfmusp.affiliation.countryEspanha
hcfmusp.affiliation.countryisoes
hcfmusp.author.externalCARMONA, Francisco:Hosp Clin Barcelona, Serv Gynecol, ICGON, Barcelona, Spain; Inst Invest Biomed August Pi & Sunyer IDIBAPS, Barcelona, Spain; Univ Barcelona, Fac Med, Barcelona, Spain
hcfmusp.citation.scopus1
hcfmusp.contributor.author-fmusphcTAINA PEZZIN ROCHA
hcfmusp.contributor.author-fmusphcMARINA DE PAULA ANDRES
hcfmusp.contributor.author-fmusphcEDMUND CHADA BARACAT
hcfmusp.contributor.author-fmusphcMAURICIO SIMOES ABRAO
hcfmusp.description.beginpage1668
hcfmusp.description.endpage1675
hcfmusp.description.issue5
hcfmusp.description.volume30
hcfmusp.origemWOS
hcfmusp.origem.pubmed36333645
hcfmusp.origem.scopus2-s2.0-85141352727
hcfmusp.origem.wosWOS:000878969400003
hcfmusp.publisher.cityHEIDELBERGeng
hcfmusp.publisher.countryGERMANYeng
hcfmusp.relation.referenceAbrao MS, 2021, REPROD SCI, V28, P675, DOI 10.1007/s43032-020-00346-9eng
hcfmusp.relation.referenceAbrao MS, 2015, HUM REPROD UPDATE, V21, P329, DOI 10.1093/humupd/dmv003eng
hcfmusp.relation.referenceAbrao MS, 2009, FERTIL STERIL, V91, P1662, DOI 10.1016/j.fertnstert.2008.02.143eng
hcfmusp.relation.referenceAliani F, 2018, J OBSTET GYNAECOL, V38, P536, DOI 10.1080/01443615.2017.1374933eng
hcfmusp.relation.referenceAnaf V, 2002, HUM REPROD, V17, P1895, DOI 10.1093/humrep/17.7.1895eng
hcfmusp.relation.referenceAndres MD, 2017, MINERVA GINECOL, V69, P587, DOI 10.23736/S0026-4784.17.04082-5eng
hcfmusp.relation.referenceAndres MP, 2018, BEST PRACT RES CL OB, V51, P111, DOI 10.1016/j.bpobgyn.2018.06.003eng
hcfmusp.relation.referenceApostolopoulos NV, 2016, ARCH GYNECOL OBSTET, V293, P439, DOI 10.1007/s00404-015-3855-2eng
hcfmusp.relation.referenceArcoverde F, 2021, MINERVA OBSTET GYNEC, V73, P341, DOI 10.23736/S2724-606X.21.04705-5eng
hcfmusp.relation.referenceBellelis P, 2010, REV ASSOC MED BRAS, V56, P467, DOI 10.1590/S0104-42302010000400022eng
hcfmusp.relation.referenceCanis M, 1997, FERTIL STERIL, V67, P817eng
hcfmusp.relation.referenceChapron C, 2003, HUM REPROD, V18, P760, DOI 10.1093/humrep/deg152eng
hcfmusp.relation.referenceChapron C, 2012, HUM REPROD, V27, P702, DOI 10.1093/humrep/der462eng
hcfmusp.relation.referenceda Cunha FL, 2021, J MINIM INVAS GYN, V28, P779, DOI 10.1016/j.jmig.2020.11.022eng
hcfmusp.relation.referenceDai Y, 2012, CHINESE MED J-PEKING, V125, P209, DOI 10.3760/cma.j.issn.0366-6999.2012.02.009eng
hcfmusp.relation.reference[戴毅 DAI Yi], 2010, [中华妇产科杂志, Chinese Journal of Obstetrics and Gynecology], V45, P93eng
hcfmusp.relation.referenceFauconnier A, 2002, FERTIL STERIL, V78, P719, DOI 10.1016/S0015-0282(02)03331-9eng
hcfmusp.relation.referenceFerrero S, 2005, FERTIL STERIL, V83, P573, DOI 10.1016/j.fertnstert.2004.07.973eng
hcfmusp.relation.referenceGabriel B, 2011, UROLOGY, V78, P1269, DOI 10.1016/j.urology.2011.07.1403eng
hcfmusp.relation.referenceHarris PA, 2009, J BIOMED INFORM, V42, P377, DOI 10.1016/j.jbi.2008.08.010eng
hcfmusp.relation.referenceHassa H, 2005, EUR J OBSTET GYN R B, V119, P82, DOI 10.1016/j.ejogrb.2004.07.025eng
hcfmusp.relation.referenceHUSKISSON EC, 1974, LANCET, V2, P1127, DOI 10.1016/S0140-6736(74)90884-8eng
hcfmusp.relation.referenceMabrouk M, 2019, J MINIM INVAS GYN, V26, P871, DOI 10.1016/j.jmig.2018.08.022eng
hcfmusp.relation.referenceMcKinnon B, 2012, FERTIL STERIL, V97, P373, DOI 10.1016/j.fertnstert.2011.11.011eng
hcfmusp.relation.referenceMenakaya U, 2014, AUST NZ J OBSTET GYN, V54, P480, DOI 10.1111/ajo.12256eng
hcfmusp.relation.referenceMontanari E, 2019, REPROD BIOMED ONLINE, V39, P845, DOI 10.1016/j.rbmo.2019.06.006eng
hcfmusp.relation.referenceParazzini F, 2001, HUM REPROD, V16, P2668eng
hcfmusp.relation.referencePeng B, 2018, REPROD SCI, V25, P540, DOI 10.1177/1933719117716778eng
hcfmusp.relation.referenceReis FM, 2020, REPROD SCI, V27, P309, DOI 10.1007/s43032-019-00028-1eng
hcfmusp.relation.referenceRoman H, 2012, HUM REPROD, V27, P3440, DOI 10.1093/humrep/des322eng
hcfmusp.relation.referenceSantulli P, 2016, HUM REPROD, V31, P1765, DOI 10.1093/humrep/dew093eng
hcfmusp.relation.referenceSchliep KC, 2015, HUM REPROD, V30, P2427, DOI 10.1093/humrep/dev147eng
hcfmusp.relation.referenceSinaii N, 2008, FERTIL STERIL, V89, P538, DOI 10.1016/j.fertnstert.2007.03.069eng
hcfmusp.relation.referenceVercellini P, 2007, HUM REPROD, V22, P266, DOI 10.1093/humrep/del339eng
hcfmusp.relation.referenceVercellini P, 1996, FERTIL STERIL, V65, P299, DOI 10.1016/S0015-0282(16)58089-3eng
hcfmusp.relation.referenceWang Yan-yan, 2010, Zhonghua Fu Chan Ke Za Zhi, V45, P260eng
hcfmusp.relation.referenceWilliams C, 2016, REPROD SCI, V23, P892, DOI 10.1177/1933719115623644eng
hcfmusp.scopus.lastupdate2024-05-17
relation.isAuthorOfPublication3099b4b3-200a-417e-baab-cd7d32ce0c22
relation.isAuthorOfPublication907264a3-10f4-48d3-97e7-a46d45702fe7
relation.isAuthorOfPublication27af1fa4-ab33-4cdc-b80d-16dd66b6ac76
relation.isAuthorOfPublication84341686-625b-4b81-a2c8-7ee41562a196
relation.isAuthorOfPublication.latestForDiscovery3099b4b3-200a-417e-baab-cd7d32ce0c22
Arquivos
Pacote Original
Agora exibindo 1 - 1 de 1
Nenhuma Miniatura disponível
Nome:
art_ROCHA_Deep_Endometriosis_the_Involvement_of_Multiple_Pelvic_Compartments_2023.PDF
Tamanho:
644.6 KB
Formato:
Adobe Portable Document Format
Descrição:
publishedVersion (English)
Baixar
Coleções
Artigos e Materiais de Revistas Científicas - FM/MOG
Artigos e Materiais de Revistas Científicas - HC/ICHC
Artigos e Materiais de Revistas Científicas - LIM/58