Weight Gain and Acute Rejection in Patients Submitted to Pulmonary Transplantation: A Retrospective Cohort of 10 Years

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dc.contributorSistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP
dc.contributor.authorARAUJO, I. Carvalho
dc.contributor.authorVIEIRA, L. Proenca
dc.contributor.authorALVES, A. C. di Creddo
dc.contributor.authorSAMANO, M. Naoyuki
dc.contributor.authorTEIXEIRA, R. H. de Oliveira Braga
dc.date.accessioned2018-07-05T18:00:48Z
dc.date.available2018-07-05T18:00:48Z
dc.date.issued2018
dc.description.abstractObjective. Acute rejection is one of the most common complications after pulmonary transplantation. The aim of this work was to verify the association of nutritional status and weight gain with acute rejection in the recipient during the 1st year after pulmonary transplantation. Methods. Retrospective cohort study with patients submitted to pulmonary transplantation at a pulmonary transplantation center in the state of Sao Paulo. Data on sex, age, underlying disease, type of transplantation, and presence, degree, and frequency of rejection according to the transbronchial biopsy results were collected, along with body mass index (BMI) and weight variation over the course of 1 year. The difference between groups was analyzed by means of Student t test and the association by means of chi-square test. Significance was considered with P < .05. Results. A total of 117 patients were included, of which 71 (60.7%) were male. The average age was 39.8 +/- 15.5 years. There were 77.8% with acute rejection in the 1st year after transplantation. The nutritional status of eutrophy prevailed according to BMI in both adolescents and adults, with no association with acute rejection (P = .80), and there was a greater weight gain among the individuals who showed rejection, with an increase of 7.58 kg (95% confidence interval [CI] 6.35-8.81) compared with those who did not present rejection, whose average weight gain was 4.12 kg (95% CI 1.28-6.95; P = .01). Conclusions. Nutritional status was not associated with acute cell rejection in the 1st year after transplantation, although weight gain was greater in those who had rejection.
dc.description.conferencedateOCT 18-21, 2017
dc.description.conferencelocalFoz do Iguacu, BRAZIL
dc.description.conferencename15th Brazilian Transplantation Congress / 16th Protuguese-Brazilian Transplantation Congress
dc.description.indexMEDLINE
dc.identifier.citationTRANSPLANTATION PROCEEDINGS, v.50, n.3, p.804-808, 2018
dc.identifier.doi10.1016/j.transproceed.2018.02.004
dc.identifier.eissn1873-2623
dc.identifier.issn0041-1345
dc.identifier.urihttps://observatorio.fm.usp.br/handle/OPI/26897
dc.language.isoeng
dc.publisherELSEVIER SCIENCE INC
dc.relation.ispartofTransplantation Proceedings
dc.rightsrestrictedAccess
dc.rights.holderCopyright ELSEVIER SCIENCE INC
dc.subject.otherbody-mass index
dc.subject.otherlung transplantation
dc.subject.otherrenal-transplantation
dc.subject.otherserum leptin
dc.subject.otherrecipients
dc.subject.othermarkers
dc.subject.otherheart
dc.subject.otherfat
dc.subject.wosImmunology
dc.subject.wosSurgery
dc.subject.wosTransplantation
dc.titleWeight Gain and Acute Rejection in Patients Submitted to Pulmonary Transplantation: A Retrospective Cohort of 10 Years
dc.typearticle
dc.type.categoryarticle; proceedings paper
dc.type.versionpublishedVersion
dspace.entity.typePublication
hcfmusp.citation.scopus0
hcfmusp.contributor.author-fmusphcISABELLE CARVALHO ARAUJO
hcfmusp.contributor.author-fmusphcLIS PROENCA VIEIRA
hcfmusp.contributor.author-fmusphcANNA CAROLINA DI CREDDO ALVES
hcfmusp.contributor.author-fmusphcMARCOS NAOYUKI SAMANO
hcfmusp.contributor.author-fmusphcRICARDO HENRIQUE DE OLIVEIRA BRAGA TEIXEIRA
hcfmusp.description.beginpage804
hcfmusp.description.endpage808
hcfmusp.description.issue3
hcfmusp.description.volume50
hcfmusp.origemWOS
hcfmusp.origem.pubmed29661442
hcfmusp.origem.scopus2-s2.0-85045569934
hcfmusp.origem.wosWOS:000432095300026
hcfmusp.publisher.cityNEW YORK
hcfmusp.publisher.countryUSA
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Artigos e Materiais de Revistas Científicas - HC/InCor
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