Urinary Bacterial Profile and Antibiotic Susceptibility in Pregnant Adolescents and Pregnant Low Obstetric Risk Adult Women

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art_SOUZA_Urinary_Bacterial_Profile_and_Antibiotic_Susceptibility_in_Pregnant_2021.PDF (494.54 KB)
Citações na Scopus
3
Tipo de produção
article
Data de publicação
2021
DOI
Scopus
Web of Science
PubMed
Título da Revista
ISSN da Revista
Título do Volume
Editora
DOVE MEDICAL PRESS LTD
Autores
DIORIO, Giselle Rodrigues Mota
Citação
INFECTION AND DRUG RESISTANCE, v.14, p.2829-2841, 2021
Projetos de Pesquisa
Unidades Organizacionais
Fascículo
Resumo
Introduction: Significant bacteriuria is associated with clinical and obstetric complications. The existing studies on the profile of urinary pathogens in pregnant women have widely divergent results and they hardly include data on pregnant adolescents. Methods: This observational retrospective study was conducted in a tertiary hospital in the city of Sao Paulo with 388 pregnant adolescents and 2547 pregnant low-risk obstetric care adults who began prenatal care between January 2010 and January 2016. They were compared in terms of urine sediment, urine culture, and antibiogram results. Results: The prevalence of bacteriuria was 17.01% (66/388) among adolescents and 10.13% (258/2547) among adults. Adolescence was a risk factor for bacteriuria in pregnancy (OR=1.82, CI95%=1.35-2.44, p=0.08). The most frequently isolated pathogen in urine culture was Escherichia coli, both in adolescents (49%) and in adults (42.18%). In positive urine cultures, urinary leukocytes were present in greater numbers in adolescents than in adults (p<0.001). Resistance to quinolones in general was more frequent among adults (OR=5.86, CI95%=0.78-44.20, p<0.001), but the tendency was not statistically significant. Conclusion: Escherichia coli and the less frequent Streptococcus agalactiae were the etiologic agents most often found in the urine cultures both of adolescents and adults. Higher rates of bacteriuria and of abnormal urine sediments prevailed among adolescents.
Palavras-chave
pregnant women, bacteriuria, pregnancy in adolescence, anti-bacterial agents, drug resistance, bacterial, microbial sensitivity tests
URI
https://observatorio.fm.usp.br/handle/OPI/41491
Referências
  1. Abat C, 2016, J INFECTION, V73, P305, DOI 10.1016/j.jinf.2016.07.012
  2. Aila NAE, 2017, PALESTINE, V25
  3. Alemu Agersew, 2012, BMC Res Notes, V5, P197, DOI 10.1186/1756-0500-5-197
  4. ALSIBAI MH, 1989, PUBLIC HEALTH, V103, P113, DOI 10.1016/S0033-3506(89)80025-3
  5. Ayoyi AO, 2017, PAN AFR MED J, V26, DOI 10.11604/pamj.2017.26.41.10975
  6. Baleiras C, 1998, Acta Med Port, V11, P839
  7. Belete MA, 2020, INFECT DRUG RESIST, V13, P1465, DOI 10.2147/IDR.S250654
  8. Calegari SS, 2010, REV BRAS GINECOL OBS, V34, P369, DOI 10.1590/S0100-72032012000800005
  9. Magalhaes MDC, 2006, REV BRAS GINECOL OBS, V28, P446, DOI 10.1590/S0100-72032006000800002
  10. Costelloe C, 2010, BMJ-BRIT MED J, V340, DOI 10.1136/bmj.c2096
  11. Demilie T, 2012, ETHIOP J HEALTH SCI, V22, P121
  12. DEMPSEY C, 1992, EUR J OBSTET GYN R B, V44, P189, DOI 10.1016/0028-2243(92)90097-I
  13. Edae M, 2020, INT J MICROBIOL, V2020, DOI 10.1155/2020/1763931
  14. Eisenstein E., 2005, ADOLESC SAUDE, P6
  15. Enayat K, 2008, INT BRAZ J UROL, V34, P699, DOI 10.1590/S1677-55382008000600004
  16. Farkash E, 2012, EUR J OBSTET GYN R B, V162, P24, DOI 10.1016/j.ejogrb.2012.01.024
  17. Geerlings SE, 2000, DIABETES CARE, V23, P744, DOI 10.2337/diacare.23.6.744
  18. Gilstrap LC, 2001, OBSTET GYN CLIN N AM, V28, P581, DOI 10.1016/S0889-8545(05)70219-9
  19. Gizachew M, 2019, ANN CLIN MICROB ANTI, V18, DOI 10.1186/s12941-019-0313-1
  20. GRATACOS E, 1994, J INFECT DIS, V169, P1390, DOI 10.1093/infdis/169.6.1390
  21. Gunes G, 2005, PUBLIC HEALTH, V119, P1039, DOI 10.1016/j.puhe.2004.11.007
  22. Hooton TM, 2000, NEW ENGL J MED, V343, P992, DOI 10.1056/NEJM200010053431402
  23. Joachim A, 2009, BMC PUBLIC HEALTH, V9, DOI 10.1186/1471-2458-9-437
  24. Johnson B, 2021, BMC PREGNANCY CHILDB, V21, DOI 10.1186/s12884-021-03641-8
  25. Kawakita T, 2016, J PEDIATR ADOL GYNEC, V29, P130, DOI 10.1016/j.jpag.2015.08.006
  26. Kazemier BM, 2015, LANCET INFECT DIS, V15, P1324, DOI 10.1016/S1473-3099(15)00070-5
  27. Le J, 2004, ANN PHARMACOTHER, V38, P1692, DOI 10.1345/aph.1D630
  28. Mathai E, 2004, APMIS, V112, P159, DOI 10.1111/j.1600-0463.2004.apm1120301.x
  29. Mazor-Dray E, 2009, J MATERN-FETAL NEO M, V22, P124, DOI 10.1080/14767050802488246
  30. MITTENDORF R, 1992, CLIN INFECT DIS, V14, P927, DOI 10.1093/clinids/14.4.927
  31. Nguefack CT, 2019, BMC PREGNANCY CHILDB, V19, DOI 10.1186/s12884-019-2290-y
  32. Nicolle LE, 2005, CLIN INFECT DIS, V40, P643, DOI 10.1086/427507
  33. Nicolle LE, 2019, CLIN INFECT DIS, V68, P1611, DOI [10.1093/cid/ciz021, 10.1093/cid/ciy1121]
  34. Obed JY, 1997, AFR J MED MED SCI, V26
  35. Oladeinde BH, 2015, ETHIOP J HEALTH SCI, V25, P3, DOI 10.4314/ejhs.v25i1.2
  36. Oli AN, 2010, NIGER J CLIN PRACT, V13, P409
  37. Onoh Rc, 2013, Infect Drug Resist, V6, P225, DOI 10.2147/IDR.S46002
  38. Onu FA, 2015, INFECT DRUG RESIST, V8, P231, DOI 10.2147/IDR.S87052
  39. Pancotto C, 2019, REV BRASILEIRA ANALI, V51, DOI [10.21877/2448-3877.201900799, DOI 10.21877/2448-3877.201900799]
  40. Pastore L M, 1999, J Perinatol, V19, P488, DOI 10.1038/sj.jp.7200264
  41. Patterson TF, 1997, INFECT DIS CLIN N AM, V11, P593, DOI 10.1016/S0891-5520(05)70375-5
  42. Pereira AC, 2011, REV BRAS ANAL CLIN, V43, P96
  43. Poulsen LL, 2012, EMERG INFECT DIS, V18, P1096, DOI 10.3201/eid1807.111754
  44. Rao GG, 2017, BMJ OPEN, V7
  45. Schenkel DF, 2014, REV BRAS GINECOL OBS, V36, P102, DOI 10.1590/S0100-72032014000300002
  46. SCHOLL TO, 1994, J ADOLESCENT HEALTH, V15, P444, DOI 10.1016/1054-139X(94)90491-K
  47. Shigemura K, 2011, J INFECT CHEMOTHER, V17, P646, DOI 10.1007/s10156-011-0241-2
  48. Sibi G, 2014, ASIAN PAC J TROP MED, V7, pS116, DOI 10.1016/S1995-7645(14)60216-9
  49. Silva LMD, 2014, ENCICLOPEDIA BIOSFER, V10, P231
  50. Sire JM, 2007, J INFECT DEV COUNTR, V1, P263, DOI 10.3855/jidc.362
  51. Stapleton AE, 2020, ANTIMICROB AGENTS CH, V64, DOI 10.1128/AAC.00862-20
  52. Sujatha R, 2014, J CLIN DIAGN RES, V8, pDC1, DOI 10.7860/JCDR/2014/6599.4205
  53. Tadesse Endale, 2014, BMC Res Notes, V7, P155, DOI 10.1186/1756-0500-7-155
  54. Thomas T, ASIAN J PHARM, V12, P3
  55. van Driel AA, 2019, EUR J CLIN MICROBIOL, V38, P2151, DOI 10.1007/s10096-019-03655-3
  56. Wing DA, 2014, AM J OBSTET GYNECOL, V210, DOI 10.1016/j.ajog.2013.10.006
  57. Yanase LE, 2018, ARQ CATARIN MED, V47, P73
  58. Yeta KI, 2021, INT J MICROBIOL, V2021, DOI 10.1155/2021/8884297

Coleções
Artigos e Materiais de Revistas Científicas - FM/MOG
Artigos e Materiais de Revistas Científicas - HC/ICHC
Artigos e Materiais de Revistas Científicas - HU
Artigos e Materiais de Revistas Científicas - LIM/57
Artigos e Materiais de Revistas Científicas - ODS/03