Areata-Like Lupus as a Clinical Manifestation of Cutaneous Lupus Erythematosus
| dc.contributor | Sistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP | |
| dc.contributor.author | MORAIS, K. L. | |
| dc.contributor.author | SECCHIN, P. | |
| dc.contributor.author | ANZAI, A. | |
| dc.contributor.author | VERUSSA, M. J. M. C. | |
| dc.contributor.author | MUNCK, A. | |
| dc.contributor.author | FECHINE, C. O. C. | |
| dc.contributor.author | VALENTE, N. Y. S. | |
| dc.contributor.author | ROMITI, R. | |
| dc.date.accessioned | 2024-03-13T20:02:48Z | |
| dc.date.available | 2024-03-13T20:02:48Z | |
| dc.date.issued | 2022 | |
| dc.description.abstract | Introduction: Lupus erythematosus (LE) is a chronic autoimmune disease that frequently causes hair loss and scalp lesions. Hair loss can be scarring and nonscarring, diffuse, or patchy. The nonscarring patchy alopecia is usually related to systemic LE (SLE) and may simulate alopecia areata (AA), reason why it is named areata-like lupus. Our case was diagnosed with areata-like lupus but did not meet criteria for SLE. Case Report: A 63-year-old woman presented with irregular nonscarring patchy alopecia in the temporal and frontoparietal scalp. Trichoscopy showed exclamation mark hairs, vellus hairs, and sparse yellow dots. Histology revealed epidermal vacuolar interface dermatitis, lymphohistiocytic infiltrate around the bulbs of anagen follicles, and eccrine glands. Direct immunofluorescence showed deposits of C3, IgA, and IgG in the basement membrane zone. Discussion: Patients with cutaneous LE can also manifest as nonscarring patchy alopecia that is clinically similar to AA, despite the absence of systemic manifestations. Areata-like lupus is secondary to the lupus autoimmune infiltrate that affects the skin including the hair follicles. Trichoscopy, histology, and direct immunofluorescence are important to differentiate this form of alopecia from AA, which is believed to have a higher incidence in lupus patients. | eng |
| dc.description.index | PubMed | |
| dc.description.index | Scopus | |
| dc.description.index | Dimensions | |
| dc.identifier.citation | SKIN APPENDAGE DISORDERS, v.8, n.4, p.322-327, 2022 | |
| dc.identifier.doi | 10.1159/000521549 | |
| dc.identifier.issn | 2296-9195 | |
| dc.identifier.uri | https://observatorio.fm.usp.br/handle/OPI/58684 | |
| dc.language.iso | eng | |
| dc.publisher | S. KARGER AG | eng |
| dc.relation.ispartof | Skin Appendage Disorders | |
| dc.rights | restrictedAccess | eng |
| dc.rights.holder | Copyright S. KARGER AG | eng |
| dc.subject | Alopecia areata | eng |
| dc.subject | Areatalike lupus | eng |
| dc.subject | Cutaneous lupus erythematosus | eng |
| dc.subject | Exclamation mark hair | eng |
| dc.subject | Tapering hair | eng |
| dc.subject.other | antinuclear antibody | eng |
| dc.subject.other | clobetasol | eng |
| dc.subject.other | losartan | eng |
| dc.subject.other | minoxidil | eng |
| dc.subject.other | triamcinolone hexacetonide | eng |
| dc.subject.other | adult | eng |
| dc.subject.other | alopecia | eng |
| dc.subject.other | alopecia areata | eng |
| dc.subject.other | article | eng |
| dc.subject.other | atrophy | eng |
| dc.subject.other | basement membrane | eng |
| dc.subject.other | case report | eng |
| dc.subject.other | clinical article | eng |
| dc.subject.other | dermatitis | eng |
| dc.subject.other | epiluminescence microscopy | eng |
| dc.subject.other | erythema | eng |
| dc.subject.other | female | eng |
| dc.subject.other | follow up | eng |
| dc.subject.other | histology | eng |
| dc.subject.other | human | eng |
| dc.subject.other | human tissue | eng |
| dc.subject.other | hyperkeratosis | eng |
| dc.subject.other | hypertension | eng |
| dc.subject.other | immunofluorescence | eng |
| dc.subject.other | middle aged | eng |
| dc.subject.other | periodic acid schiff stain | eng |
| dc.subject.other | physical examination | eng |
| dc.subject.other | scanty hair | eng |
| dc.subject.other | skin lupus erythematosus | eng |
| dc.subject.other | telangiectasia | eng |
| dc.subject.other | trichoscopy | eng |
| dc.subject.other | vellus hair | eng |
| dc.title | Areata-Like Lupus as a Clinical Manifestation of Cutaneous Lupus Erythematosus | eng |
| dc.type | article | eng |
| dc.type.category | original article | eng |
| dc.type.version | publishedVersion | eng |
| dspace.entity.type | Publication | |
| hcfmusp.author.external | SECCHIN, P.:Department of Dermatology, Hospital das Clínicas, University of São Paulo, São Paulo, Brazil | |
| hcfmusp.author.external | VERUSSA, M. J. M. C.:Department of Dermatology, Hospital das Clínicas, University of São Paulo, São Paulo, Brazil | |
| hcfmusp.citation.scopus | 0 | |
| hcfmusp.contributor.author-fmusphc | KARINA LOPES MORAIS | |
| hcfmusp.contributor.author-fmusphc | ALESSANDRA ANZAI | |
| hcfmusp.contributor.author-fmusphc | ANDREIA MUNCK DE ALMEIDA | |
| hcfmusp.contributor.author-fmusphc | CAROLINA OLIVEIRA COSTA FECHINE | |
| hcfmusp.contributor.author-fmusphc | NEUSA YURIKO SAKAI VALENTE | |
| hcfmusp.contributor.author-fmusphc | RICARDO ROMITI | |
| hcfmusp.description.beginpage | 322 | |
| hcfmusp.description.endpage | 327 | |
| hcfmusp.description.issue | 4 | |
| hcfmusp.description.volume | 8 | |
| hcfmusp.origem | SCOPUS | |
| hcfmusp.origem.dimensions | pub.1145532757 | |
| hcfmusp.origem.scopus | 2-s2.0-85126026033 | |
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