Characterization of pain syndromes in patients with neuromyelitis optica

Imagem de Miniatura
Arquivos
art_VALERIO_Characterization_of_pain_syndromes_in_patients_with_neuromyelitis_2020.PDF (960.54 KB)
Citações na Scopus
16
Tipo de produção
article
Data de publicação
2020
DOI
Scopus
Web of Science
PubMed
Título da Revista
ISSN da Revista
Título do Volume
Editora
WILEY
Autores
Citação
EUROPEAN JOURNAL OF PAIN, v.24, n.8, p.1548-1568, 2020
Projetos de Pesquisa
Unidades Organizacionais
Fascículo
Resumo
Background Pain is common and refractory in spinal cord injury (SCI). Currently, most studies evaluated pain in male-predominant traumatic-SCI. Also, concomitant secondary pain syndromes and its temporal evolution were seldom reported. Methods We aimed to prospectively describe the main and secondary pain and its associated factors in inflammatory-SCI evaluating neuromyelitis optica (NMO) patients. In-remission NMO patients underwent neurological, imaging and autoantibody evaluations. Questionnaires detailing main and secondary pains, functional state, mood, catastrophizing, quality of life (QoL) and ""non-motor symptoms"" were used at two time points. Results Pain was present in 53 (73.6%) of the 72 patients included. At-level neuropathic pain was the most common main pain syndrome, affecting 32 subjects (60.4% of those with pain). Over 70% (n = 38) of this cohort reported two pain syndromes. Those without pain were significantly younger (26.1 +/- 12.7 y.o. in those without pain and 40.1 +/- 12.5, 37.2 +/- 11.4 y.o. in those whose main pain was neuropathic and non-neuropathic, respectively,p = .001), and no differences in the inflammatory status were observed between groups. On follow-up, one-fifth (n = 11) had a different main pain syndrome from the first visit. Pain impacted QoL as much as disability and motor strength. Conclusion Pain is a prevalent and disabling non-motor symptom in NMO-SCI. Most patients experience more than one pain syndrome which can change in time even in the absence of clinical relapse. Age of the inflammatory-SCI was a major determinant of pain. Acknowledging temporal changes and multiplicity of pain syndromes in NMO-SCI may give insights into more precise designs of clinical trials and general management of pain in SCI. Significance In this longitudinal study with NMO-related SCI, pain affected almost three-quarters of patients with NMO. Over 70% have more than one pain syndrome and at-level neuropathic pain is the most common type of pain syndrome. Patients without pain were significantly younger but had the same burden of inflammatory lesions than those with pain. During follow-up, up to one fifth of patients presented with changes in the main pain syndromes, which can occur even in the absence of clinical activity of the inflammatory disease. In this cohort, Pain affected quality of life as much as disability or motor strength.
Palavras-chave
URI
https://observatorio.fm.usp.br/handle/OPI/37784
Referências
  1. Acquadro C, 2006, UROLOGY, V67, P536, DOI 10.1016/j.urology.2005.09.035
  2. Akaishi T, 2017, NEUROIMAG CLIN N AM, V27, P251, DOI 10.1016/j.nic.2016.12.010
  3. Akaishi T, 2016, J NEUROL NEUROSUR PS, V87, P446, DOI 10.1136/jnnp-2014-310206
  4. Anderson K, 2008, J SPINAL CORD MED, V31, P133, DOI 10.1080/10790268.2008.11760704
  5. Asgari N, 2013, DAN MED J, V60
  6. Ashcroft GS, 2002, BIOGERONTOLOGY, V3, P337, DOI 10.1023/A:1021399228395
  7. BARRY MJ, 1992, J UROLOGY, V148, P1549, DOI 10.1016/S0022-5347(17)36966-5
  8. BERTOLUCCI PHF, 1994, ARQ NEURO-PSIQUIAT, V52, P1, DOI 10.1590/S0004-282X1994000100001
  9. Bharucha AE, 2013, GASTROENTEROLOGY, V144, P218, DOI 10.1053/j.gastro.2012.10.028
  10. Boogaard S, 2015, PAIN PHYSICIAN, V18, P433
  11. Botega NJ, 1995, REV SAUDE PUBL, V29, P355, DOI 10.1590/S0034-89101995000500004
  12. Bouhassira D, 2004, PAIN, V108, P248, DOI 10.1016/j.pain.2003.12.024
  13. Brucki SMD, 2003, ARQ NEURO-PSIQUIAT, V61, P777, DOI 10.1590/S0004-282X2003000500014
  14. Bryce TN, 2012, SPINAL CORD, V50, P413, DOI 10.1038/sc.2011.156
  15. Bryce TN, 2012, SPINAL CORD, V50, P404, DOI 10.1038/sc.2012.2
  16. Bryce TN, 2007, J SPINAL CORD MED, V30, P421, DOI 10.1080/10790268.2007.11753405
  17. Buckalew N, 2008, PAIN MED, V9, P240, DOI 10.1111/j.1526-4637.2008.00412.x
  18. Burke D, 2018, EUR J PAIN, V22, P1662, DOI 10.1002/ejp.1248
  19. Burke D, 2017, EUR J PAIN, V21, P29, DOI 10.1002/ejp.905
  20. Campbell W. W., 2005, DEJONGS NEUROLOGICAL
  21. Chen JJ, 2018, AM J OPHTHALMOL, V195, P8, DOI 10.1016/j.ajo.2018.07.020
  22. Crutcher KA, 2002, AUTON NEUROSCI-BASIC, V96, P25, DOI 10.1016/S1566-0702(01)00373-3
  23. Cury RG, 2014, NEUROLOGY, V83, P1403, DOI 10.1212/WNL.0000000000000887
  24. da Silva LA, 2014, ORAL DIS, V20, pe103, DOI 10.1111/odi.12145
  25. DAUT RL, 1983, PAIN, V17, P197, DOI 10.1016/0304-3959(83)90143-4
  26. de Andrade DC, 2011, HEALTH QUAL LIFE OUT, V9, DOI 10.1186/1477-7525-9-107
  27. de Seze J, 2019, CURR OPIN NEUROL, V32, P111, DOI 10.1097/WCO.0000000000000650
  28. de Souza JB, 2017, PAIN RES MANAG, V2017, DOI 10.1155/2017/4643830
  29. Dijkers M, 2009, J REHABIL RES DEV, V46, P13, DOI 10.1682/JRRD.2008.04.0053
  30. Ducreux D, 2006, BRAIN, V129, P963, DOI 10.1093/brain/awl016
  31. Edwards CL, 2001, PAIN, V94, P133, DOI 10.1016/S0304-3959(01)00408-0
  32. Fabis-Pedrini MJ, 2018, J NEUROIMMUNOL, V324, P76, DOI 10.1016/j.jneuroim.2018.09.006
  33. Ferreira KA, 2011, SUPPORT CARE CANCER, V19, P505, DOI 10.1007/s00520-010-0844-7
  34. Fillingim RB, 2016, J PAIN, V17, pT10, DOI 10.1016/j.jpain.2015.08.010
  35. Finnerup NB, 2016, SPINAL CORD, V54, P816, DOI 10.1038/sc.2015.236
  36. Finnerup NB, 2016, PAIN, V157, P1599, DOI 10.1097/j.pain.0000000000000492
  37. Finnerup NB, 2015, LANCET NEUROL, V14, P162, DOI 10.1016/S1474-4422(14)70251-0
  38. Finnerup NB, 2014, J PAIN, V15, P40, DOI 10.1016/j.jpain.2013.09.008
  39. Finnerup NB, 2013, PAIN, V154, pS71, DOI 10.1016/j.pain.2012.12.007
  40. Finnerup NB, 2012, CURR PAIN HEADACHE R, V16, P207, DOI 10.1007/s11916-012-0259-x
  41. Finnerup NB, 2004, EUR J NEUROL, V11, P73, DOI 10.1046/j.1351-5101.2003.00725.x
  42. Fitzgerald M, 2016, EXP NEUROL, V275, P296, DOI 10.1016/j.expneurol.2015.07.013
  43. Flanagan EP, 2016, ANN NEUROL, V79, P775, DOI 10.1002/ana.24617
  44. FLOR H, 1993, BEHAV RES THER, V31, P63, DOI 10.1016/0005-7967(93)90044-U
  45. Foley PL, 2013, PAIN, V154, P632, DOI 10.1016/j.pain.2012.12.002
  46. FOLSTEIN MF, 1975, J PSYCHIAT RES, V12, P189, DOI 10.1016/0022-3956(75)90026-6
  47. Freynhagen R, 2019, CURR MED RES OPIN, V35, P1011, DOI 10.1080/03007995.2018.1552042
  48. Gagliese L, 2009, J PAIN, V10, P343, DOI 10.1016/j.jpain.2008.10.013
  49. Galhardoni GR, 2019, NEUROLOGY, V92, pE2165, DOI 10.1212/WNL.0000000000007396
  50. Ge HY, 2004, PAIN, V110, P72, DOI 10.1016/j.pain.2004.03.005
  51. Gibson SJ, 2004, CLIN J PAIN, V20, P227, DOI 10.1097/00002508-200407000-00004
  52. Guergova S, 2011, AGEING RES REV, V10, P80, DOI 10.1016/j.arr.2010.04.009
  53. Haanpaa M, 2011, PAIN, V152, P14, DOI 10.1016/j.pain.2010.07.031
  54. HALLETT M, 1993, NEUROLOGY, V43, P2723, DOI 10.1212/WNL.43.12.2723
  55. Harden RN, 2005, J PAIN, V6, P364, DOI 10.1016/j.jpain.2005.01.350
  56. Helme RD, 2018, PAIN, V159, P1005, DOI 10.1097/j.pain.0000000000001149
  57. Hulsebosch CE, 2009, BRAIN RES REV, V60, P202, DOI 10.1016/j.brainresrev.2008.12.010
  58. Jarius S, 2016, J NEUROINFLAMM, V13, DOI 10.1186/s12974-016-0718-0
  59. Jenkinson C, 1997, J PUBLIC HEALTH MED, V19, P179, DOI 10.1093/oxfordjournals.pubmed.a024606
  60. Kanamori Y, 2011, NEUROLOGY, V77, P652, DOI 10.1212/WNL.0b013e318229e694
  61. KATZ RT, 1992, ARCH PHYS MED REHAB, V73, P339, DOI 10.1016/0003-9993(92)90007-J
  62. Kim HJ, 2015, NEUROLOGY, V84, P1165, DOI 10.1212/WNL.0000000000001367
  63. Kim SM, 2012, ARCH NEUROL-CHICAGO, V69, P1026, DOI 10.1001/archneurol.2012.112
  64. Kim W, 2010, MULT SCLER J, V16, P1229, DOI 10.1177/1352458510376640
  65. Kitley J, 2014, JAMA NEUROL, V71, P276, DOI 10.1001/jamaneurol.2013.5857
  66. Kitley J, 2012, NEUROLOGY, V79, P1273, DOI 10.1212/WNL.0b013e31826aac4e
  67. Kong YZ, 2016, J NEUROL SCI, V368, P84, DOI 10.1016/j.jns.2016.06.041
  68. KRUPP LB, 1989, ARCH NEUROL-CHICAGO, V46, P1121, DOI 10.1001/archneur.1989.00520460115022
  69. KURTZKE JF, 1983, NEUROLOGY, V33, P1444, DOI 10.1212/WNL.33.11.1444
  70. Lanteri-Minet M, 2005, CEPHALALGIA, V25, P1146, DOI 10.1111/j.1468-2982.2005.00977.x
  71. Lariviere M, 2007, CLIN J PAIN, V23, P506, DOI 10.1097/AJP.0b013e31806a23e8
  72. Ferreira KASL, 2016, ARQ NEURO-PSIQUIAT, V74, P990, DOI [10.1590/0004-282X20160156, 10.1590/0004-282x20160156]
  73. Lipton RB, 2007, NEUROLOGY, V68, P343, DOI 10.1212/01.wnl.0000252808.97649.21
  74. MAHONEY F I, 1965, Md State Med J, V14, P61
  75. MELZACK R, 1987, PAIN, V30, P191, DOI 10.1016/0304-3959(87)91074-8
  76. Mendes MF, 1998, ARQ NEURO-PSIQUIAT, V56, P160
  77. Merskey H., 1994, IASP TASK FORCE TAXO
  78. Moisset X, 2017, EUR J PAIN, V21, P1297, DOI 10.1002/ejp.1077
  79. Moisset X, 2013, PAIN, V154, P2691, DOI 10.1016/j.pain.2013.07.050
  80. Mordillo-Mateos L, 2019, SPINAL CORD, V57, P953, DOI 10.1038/s41393-019-0311-3
  81. Muto M, 2015, EUR J NEUROL, V22, P299, DOI 10.1111/ene.12566
  82. Nurmikko T, 2009, EUR J NEUROL, V16, pE104, DOI 10.1111/j.1468-1331.2009.02583.x
  83. O'Connor AB, 2008, PAIN, V137, P96, DOI 10.1016/j.pain.2007.08.024
  84. Okifuji A, 1997, J RHEUMATOL, V24, P377
  85. Paquette IM, 2015, DIS COLON RECTUM, V58, P623, DOI 10.1097/DCR.0000000000000397
  86. Peres MFP, 2019, J HEADACHE PAIN, V20, DOI 10.1186/s10194-019-1036-6
  87. Putzke JD, 2002, SPINAL CORD, V40, P118, DOI 10.1038/sj.sc.3101269
  88. Qian PQ, 2012, ARCH NEUROL-CHICAGO, V69, P1482, DOI 10.1001/archneurol.2012.768
  89. Queiroz LP, 2009, CEPHALALGIA, V29, P642, DOI 10.1111/j.1468-2982.2008.01782.x
  90. Richardson Amy, 2019, J Spinal Cord Med, P1, DOI 10.1080/10790268.2019.1581392
  91. Rintala DH, 1998, ARCH PHYS MED REHAB, V79, P604, DOI 10.1016/S0003-9993(98)90032-6
  92. Rosier EM, 2002, PAIN, V98, P205, DOI 10.1016/S0304-3959(02)00048-9
  93. Santos JG, 2010, J PAIN, V11, P484, DOI 10.1016/j.jpain.2009.09.014
  94. Ferreira KAS, 2013, PAIN MANAG NURS, V14, P210, DOI 10.1016/j.pmn.2011.04.006
  95. Sarda Junior J, 2008, ACTA FISIATR, V15, P31, DOI 10.5935/0104-7795.20080001
  96. Sato DK, 2014, NEUROLOGY, V82, P474, DOI 10.1212/WNL.0000000000000101
  97. Sato DK, 2013, NEUROLOGY, V80, P2210, DOI 10.1212/WNL.0b013e318296ea08
  98. Sepulveda M, 2018, MULT SCLER J, V24, P1843, DOI 10.1177/1352458517735191
  99. Siddall PJ, 2003, PAIN, V103, P249, DOI 10.1016/S0304-3959(02)00452-9
  100. Sullivan MJL, 1995, PSYCHOL ASSESSMENT, V7, P524, DOI 10.1037/1040-3590.7.4.524
  101. Tackley G, 2017, J NEUROL NEUROSUR PS, V88, P165, DOI 10.1136/jnnp-2016-314991
  102. Teixeira M. J., 2018, DOR MANUAL CLIN
  103. Treede RD, 2008, NEUROLOGY, V70, P1630, DOI 10.1212/01.wnl.0000282763.29778.59
  104. Treede RD, 2019, PAIN, V160, P19, DOI 10.1097/j.pain.0000000000001384
  105. Vierck CJ, 2015, EUR J PAIN, V19, P1158, DOI 10.1002/ejp.640
  106. Ware JE, 1996, MED CARE, V34, P220, DOI 10.1097/00005650-199603000-00003
  107. Weinshenker BG, 2017, MAYO CLIN PROC, V92, P663, DOI 10.1016/j.mayocp.2016.12.014
  108. Widerstrom-Noga EG, 2001, ARCH PHYS MED REHAB, V82, P1571, DOI 10.1053/apmr.2001.26068
  109. Wingerchuk DM, 2006, NEUROLOGY, V66, P1485, DOI 10.1212/01.wnl.0000216139.44259.74
  110. Wingerchuk DM, 2007, LANCET NEUROL, V6, P805, DOI 10.1016/S1474-4422(07)70216-8
  111. Wingerchuk DM, 2015, NEUROLOGY, V85, P177, DOI 10.1212/WNL.0000000000001729
  112. Zeilig G, 2012, BRAIN, V135, P418, DOI 10.1093/brain/awr270
  113. Zheng Z, 2000, PAIN, V85, P51, DOI 10.1016/S0304-3959(99)00247-X
  114. ZIGMOND AS, 1983, ACTA PSYCHIAT SCAND, V67, P361, DOI 10.1111/j.1600-0447.1983.tb09716.x

Coleções
Artigos e Materiais de Revistas Científicas - FM/MNE
Artigos e Materiais de Revistas Científicas - HC/ICESP
Artigos e Materiais de Revistas Científicas - HC/ICHC
Artigos e Materiais de Revistas Científicas - HC/InRad
Artigos e Materiais de Revistas Científicas - LIM/44
Artigos e Materiais de Revistas Científicas - LIM/45
Carregar mais