Facial Structure Alterations and Abnormalities of the Paranasal Sinuses on Multidetector Computed Tomography Scans of Patients with Treated Mucosal Leishmaniasis

Página do item simplificado
dc.contributorSistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP
dc.contributor.authorCAMARGO, Raphael Abegao de
dc.contributor.authorNICODEMO, Antonio C.
dc.contributor.authorSUMI, Daniel Vaccaro
dc.contributor.authorGEBRIM, Eloisa Maria Mello Santiago
dc.contributor.authorTUON, Felipe Francisco
dc.contributor.authorCAMARGO, Lazaro Manoel de
dc.contributor.authorIMAMURA, Rui
dc.contributor.authorAMATO, Valdir Sabbaga
dc.date.accessioned2015-02-06T19:43:01Z
dc.date.available2015-02-06T19:43:01Z
dc.date.issued2014
dc.description.abstractBackground/Objectives: Mucosal leishmaniasis (ML) is a progressive disease that affects cartilage and bone structures of the nose and other upper respiratory tract structures. Complications associated with ML have been described, but there is a lack of studies that evaluate the structural changes of the nose and paranasal sinuses in ML using radiological methods. In this study, we aimed to assess the opacification of the paranasal sinuses in patients with treated ML and any anatomical changes in the face associated with ML using multidetector computed tomography scans (MDCT) of the sinuses. We compared the findings with a control group. Methodology/Principal Findings: We evaluated 54 patients with treated ML who underwent CT scans of the sinuses and compared them with a control group of 40 patients who underwent orbital CT scans. The degree of sinus disease was assessed according to the Lund-Mackay criteria. Forty of the 54 patients with a history of ML (74.1%) had a tomographic score compatible with chronic sinusitis (Lund-Mackay >= 4). CT scans in the leishmaniasis and control groups demonstrated significant differences in terms of facial structure alterations. Patients from the ML group showed more severe levels of partial opacification and pansinus mucosal thickening (42.6%) and a greater severity of total opacification. Patients from the ML group with a Lund-Mackay score >= 4 presented longer durations of disease before treatment and more severe presentations of the disease at diagnosis. Conclusion/Significance: CT scans of the sinuses of patients with ML presented several structural alterations, revealing a prominent destructive feature of the disease. The higher prevalence in this study of chronic rhinosinusitis observed in CT scans of patients with treated ML than in those of the control group suggests that ML can be considered a risk factor for chronic rhinosinusitis in this population (p<0.05).
dc.description.indexMEDLINE
dc.identifier.citationPLOS NEGLECTED TROPICAL DISEASES, v.8, n.7, article ID e3001, 13p, 2014
dc.identifier.doi10.1371/journal.pntd.0003001
dc.identifier.issn1935-2735
dc.identifier.urihttps://observatorio.fm.usp.br/handle/OPI/8456
dc.language.isoeng
dc.publisherPUBLIC LIBRARY SCIENCE
dc.relation.ispartofPlos Neglected Tropical Diseases
dc.rightsopenAccess
dc.rights.holderCopyright PUBLIC LIBRARY SCIENCE
dc.subject.otherchronic rhinosinusitis
dc.subject.otherseptal perforation
dc.subject.othermucocutaneous leishmaniasis
dc.subject.otherstaging systems
dc.subject.otherin-situ
dc.subject.otherdiagnosis
dc.subject.otherprevalence
dc.subject.othersimulation
dc.subject.wosInfectious Diseases
dc.subject.wosParasitology
dc.subject.wosTropical Medicine
dc.titleFacial Structure Alterations and Abnormalities of the Paranasal Sinuses on Multidetector Computed Tomography Scans of Patients with Treated Mucosal Leishmaniasis
dc.typearticle
dc.type.categoryoriginal article
dc.type.versionpublishedVersion
dspace.entity.typePublication
hcfmusp.author.externalSUMI, Daniel Vaccaro:Univ Sao Paulo, Sch Med, Hosp Clin, Inst Radiol, Sao Paulo, Brazil
hcfmusp.author.externalTUON, Felipe Francisco:Univ Fed Parana, Div Infect Dis, BR-80060000 Curitiba, Parana, Brazil; Hosp Univ Evangel Curitiba, Div Infect & Parasit Dis, Curitiba, Parana, Brazil
hcfmusp.author.externalCAMARGO, Lazaro Manoel de:Univ Cuiaba, Sch Vet Med, Cuiaba, Mato Grosso, Brazil
hcfmusp.citation.scopus11
hcfmusp.contributor.author-fmusphcRAPHAEL ABEGAO DE CAMARGO
hcfmusp.contributor.author-fmusphcANTONIO CARLOS NICODEMO
hcfmusp.contributor.author-fmusphcELOISA MARIA MELLO SANTIAGO GEBRIM
hcfmusp.contributor.author-fmusphcRUI IMAMURA
hcfmusp.contributor.author-fmusphcVALDIR SABBAGA AMATO
hcfmusp.description.articlenumbere3001
hcfmusp.description.issue7
hcfmusp.description.volume8
hcfmusp.origemWOS
hcfmusp.origem.scopus2-s2.0-84905474646
hcfmusp.origem.wosWOS:000340551500048
hcfmusp.publisher.citySAN FRANCISCO
hcfmusp.publisher.countryUSA
hcfmusp.relation.referenceAmato VS, 2008, ACTA TROP, V105, P1, DOI 10.1016/j.actatropica.2007.08.003
hcfmusp.relation.referenceAmato VS, 2003, AM J TROP MED HYG, V68, P527
hcfmusp.relation.referenceAmato VS, 2003, ACTA TROP, V85, P39, DOI 10.1016/S0001-706X(02)00260-7
hcfmusp.relation.referenceAmato VS, 2009, J EUR ACAD DERMATOL, V23, P1026, DOI 10.1111/j.1468-3083.2009.03238.x
hcfmusp.relation.referenceAmato V S, 1995, Rev Soc Bras Med Trop, V28, P129
hcfmusp.relation.referenceAshraf N, 2001, OTOLARYNG HEAD NECK, V125, P483, DOI 10.1016/S0194-5998(01)43777-6
hcfmusp.relation.referenceBhattacharyya N, 2010, OTOLARYNG HEAD NECK, V143, P147, DOI 10.1016/j.otohns.2010.04.012
hcfmusp.relation.referenceBhattacharyya N, 2007, LARYNGOSCOPE, V117, P691, DOI 10.1097/01.mlg.0000256455.01473.72
hcfmusp.relation.referenceBhattacharyya N, 2003, LARYNGOSCOPE, V113, P125, DOI 10.1097/00005537-200301000-00023
hcfmusp.relation.referenceBoaventura VS, 2009, AM J TROP MED HYG, V81, P384
hcfmusp.relation.referenceCALHOUN KH, 1991, OTOLARYNG HEAD NECK, V104, P480
hcfmusp.relation.referenceCamargo RA, 2010, AM J TROP MED HYG, V83, P515, DOI 10.4269/ajtmh.2010.10-0081
hcfmusp.relation.referenceCannon DE, 2013, OTOLARYNG HEAD NECK, V148, P513, DOI 10.1177/0194599812472881
hcfmusp.relation.referenceDesjeux P, 2004, COMP IMMUNOL MICROB, V27, P305, DOI 10.1016/j.cimid.2004.03.004
hcfmusp.relation.referenceFLINN J, 1994, CLIN OTOLARYNGOL, V19, P287, DOI 10.1111/j.1365-2273.1994.tb01232.x
hcfmusp.relation.referenceGeorgalas C, 2013, CURR OPIN OTOLARYNGO, V21, P45, DOI 10.1097/MOO.0b013e32835ac656
hcfmusp.relation.referenceGRANT A, 1994, J LARYNGOL OTOL, V108, P1086
hcfmusp.relation.referenceGrindler D, 2009, AMJ RHINOL ALLERGY, V23, P497, DOI 10.2500/ajra.2009.23.3359
hcfmusp.relation.referenceHastan D, 2011, ALLERGY, V66, P1216, DOI 10.1111/j.1398-9995.2011.02646.x
hcfmusp.relation.referenceHAVAS TE, 1988, ARCH OTOLARYNGOL, V114, P856
hcfmusp.relation.referenceHopkins C, 2007, OTOLARYNG HEAD NECK, V137, P555, DOI 10.1016/j.otohns.2007.02.004
hcfmusp.relation.referenceLee HP, 2010, J LARYNGOL OTOL, V124, P48, DOI 10.1017/S0022215109990971
hcfmusp.relation.referenceLlanosCuentas A, 1997, CLIN INFECT DIS, V25, P677, DOI 10.1086/513776
hcfmusp.relation.referenceLund Valerie J., 1993, Rhinology (Utrecht), V31, P183
hcfmusp.relation.referenceLund VJ, 1997, OTOLARYNG HEAD NECK, V117, pS35, DOI 10.1016/S0194-5998(97)70005-6
hcfmusp.relation.referenceMARSDEN PD, 1986, T ROY SOC TROP MED H, V80, P859, DOI 10.1016/0035-9203(86)90243-9
hcfmusp.relation.referenceMeltzer EO, 2004, OTOLARYNG HEAD NECK, V131, pS1, DOI 10.1016/j.otohns.2004.09.067
hcfmusp.relation.referenceMetson R, 1997, OTOLARYNG HEAD NECK, V117, P372, DOI 10.1016/S0194-5998(97)70129-3
hcfmusp.relation.referenceMurray HW, 2005, LANCET, V366, P1561, DOI 10.1016/S0140-6736(05)67629-5
hcfmusp.relation.referenceOkushi T, 2013, AURIS NASUS LARYNX, V40, P548, DOI 10.1016/j.anl.2013.04.010
hcfmusp.relation.referenceOluwole M, 1996, CLIN OTOLARYNGOL, V21, P91
hcfmusp.relation.referencePalheta Neto FX, 2008, ARQ INT OTORRINOLARI, V12, P531
hcfmusp.relation.referencePilan RRD, 2012, RHINOLOGY, V50, P129, DOI 10.4193/Rhino11.256
hcfmusp.relation.referencePless D, 2004, AM J RHINOL, V18, P357
hcfmusp.relation.referenceRazek AAKA, 2010, EUR J RADIOL, V76, P52, DOI 10.1016/j.ejrad.2009.05.021
hcfmusp.relation.referenceSchwartz E, 2006, LANCET INFECT DIS, V6, P342, DOI 10.1016/S1473-3099(06)70492-3
hcfmusp.relation.referenceSedaghat AR, 2012, INT FORUM ALLERGY RH, V2, P386, DOI 10.1002/alr.21042
hcfmusp.relation.referenceVlaid S, 2010, CLIN RADIOL, V65, P73
hcfmusp.relation.referenceWorld Health Organization, 2010, WHO TECH REP SER, V949, P1
hcfmusp.scopus.lastupdate2024-05-10
relation.isAuthorOfPublication4dbceab8-6b7d-4f0d-84ad-98ed3a5fbe32
relation.isAuthorOfPublication059a0991-97bb-4c31-9941-4c7367eb4050
relation.isAuthorOfPublicationcbc88228-5097-4ebf-ac63-b45310c6b646
relation.isAuthorOfPublication7913d449-112d-4a05-a6c4-dbe5aa0923a2
relation.isAuthorOfPublication8605618c-a3c4-44f8-bda7-e86858789a79
relation.isAuthorOfPublication.latestForDiscovery4dbceab8-6b7d-4f0d-84ad-98ed3a5fbe32
Arquivos
Pacote Original
Agora exibindo 1 - 1 de 1
Imagem de Miniatura
Nome:
art_CAMARGO_Facial_Structure_Alterations_and_Abnormalities_of_the_Paranasal_2014.PDF
Tamanho:
2.09 MB
Formato:
Adobe Portable Document Format
Descrição:
publishedVersion (English)
Baixar
Coleções
Artigos e Materiais de Revistas Científicas - FM/MIP
Artigos e Materiais de Revistas Científicas - HC/ICHC
Artigos e Materiais de Revistas Científicas - HC/InRad
Artigos e Materiais de Revistas Científicas - LIM/32
Artigos e Materiais de Revistas Científicas - LIM/46