Influence of demographics on clinical outcome of dengue: a cross-sectional study of 6703 confirmed cases in Vitoria, Espirito Santo State, Brazil

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art_VICENTE_Influence_of_demographics_on_clinical_outcome_of_dengue_2017.PDF (149.11 KB)
Citações na Scopus
8
Tipo de produção
article
Data de publicação
2017
DOI
Scopus
Web of Science
PubMed
Título da Revista
ISSN da Revista
Título do Volume
Editora
CAMBRIDGE UNIV PRESS
Autores
VICENTE, C. R.
CERUTTI JUNIOR, C.
FROESCHL, G.
CABIDELLE, A. S. A.
HERBINGER, K. -H.
Citação
EPIDEMIOLOGY AND INFECTION, v.145, n.1, p.46-53, 2017
Projetos de Pesquisa
Unidades Organizacionais
Fascículo
Resumo
Dengue presents a wide clinical spectrum of signs and symptoms, with characteristics of the host potentially influencing the disease evolution. Therefore, the purpose of this study was to evaluate the influence of gender and age on dengue clinical outcomes in a recent outbreak situation in Brazil, applying a cross-sectional design and including 6703 dengue cases with laboratory confirmation, occurring in Vitoria, Espirito Santo State, Brazil, between 2007 and 2013. Data were obtained from the Information System for Notifiable Diseases. Overall, 11<bold></bold>3% of the sample presented with severe dengue, which affected 13<bold></bold>0% of males, 10<bold></bold>0% of females, 8<bold></bold>8% of children, 12<bold></bold>5% of adolescents, 10<bold></bold>5% of adults and 15<bold></bold>5% of the elderly. Age was higher in the severe dengue group (P = 0<bold></bold>03). Severe dengue was associated with males and the elderly (P < 0<bold></bold>01); however, considering only severe cases, children presented haemorrhage and plasma leakage more frequently than older age groups. The results emphasize the importance of a differentiated protocol for management of dengue cases, taking into consideration host factors like age. These findings also suggest the elderly and children as priority groups for immunization in a future implementation of a vaccine.
Palavras-chave
Age groups, severe dengue, sex, signs and symptoms
URI
https://observatorio.fm.usp.br/handle/OPI/18143
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Coleções
Artigos e Materiais de Revistas Científicas - LIM/52
Artigos e Materiais de Revistas Científicas - ODS/03