Peripheral Artery Disease Diagnosed by Pulse Palpation as a Predictor of Coronary Artery Disease in Patients with Chronic Kidney Disease

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dc.contributorSistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP
dc.contributor.authorSANTOS, Daniel B. C. Dos
dc.contributor.authorGOWDAK, Luis Henrique W.
dc.contributor.authorDAVID-NETO, Elias
dc.contributor.authorNATANIEL, Felizardo A.
dc.contributor.authorLIMA, Jose J. G. De
dc.contributor.authorBORTOLOTTO, Luiz A.
dc.date.accessioned2023-12-15T18:45:26Z
dc.date.available2023-12-15T18:45:26Z
dc.date.issued2023
dc.description.abstractThere is a need of simple, inexpensive, and reliable noninvasive testing to predict coronary artery disease (CAD) in patients with chronic kidney disease (CKD), where the prevalence of cardiovascular (CV) events and death is elevated. We analyzed the association between peripheral artery disease (PAD) and CAD in 201 patients with stage 5 CKD on dialysis using a prospective observational cohort. Diagnosis of PAD by both palpation and USD were significantly correlated. In patients with PAD diagnosed by palpation, CAD was observed in 80%, while in those diagnosed by USD, CAD was present in 79.1%. The absence of a pulse by palpation predicted CAD with a sensitivity of 55% and a specificity of 76%; USD showed a sensitivity of 62% and specificity of 60% to predict CAD. The risk of combined serious CV events and death was significantly higher in subjects with PAD diagnosed by palpation, but not by USD. PAD assessed by palpation also correlated with the occurrence of multivessel CAD and with the probability of coronary intervention. Both methods are moderately useful for predicting CAD, but PAD diagnosis by palpation was a better predictor of combined CV events and death and was also associated with CAD severity and likelihood of intervention.eng
dc.description.indexPubMed
dc.description.indexWoS
dc.description.indexScopus
dc.description.sponsorshipWe thank InCor and all those involved in carrying out this study.
dc.identifier.citationJOURNAL OF CLINICAL MEDICINE, v.12, n.18, article ID 5882, 10p, 2023
dc.identifier.doi10.3390/jcm12185882
dc.identifier.eissn2077-0383
dc.identifier.urihttps://observatorio.fm.usp.br/handle/OPI/57373
dc.language.isoeng
dc.publisherMDPIeng
dc.relation.ispartofJournal of Clinical Medicine
dc.rightsopenAccesseng
dc.rights.holderCopyright MDPIeng
dc.subjectchronic kidney diseaseeng
dc.subjectperipheral artery diseaseeng
dc.subjectcoronary artery diseaseeng
dc.subjectpulse palpationeng
dc.subjectdoppler ultra soundeng
dc.subject.otherfrequencyeng
dc.subject.wosMedicine, General & Internaleng
dc.titlePeripheral Artery Disease Diagnosed by Pulse Palpation as a Predictor of Coronary Artery Disease in Patients with Chronic Kidney Diseaseeng
dc.typearticleeng
dc.type.categoryoriginal articleeng
dc.type.versionpublishedVersioneng
dspace.entity.typePublication
hcfmusp.author.externalNATANIEL, Felizardo A.:Univ Sao Paulo, Hosp Clin, Heart Inst InCor, Med Sch, BR-05403000 Sao Paulo, Brazil
hcfmusp.citation.scopus0
hcfmusp.contributor.author-fmusphcDANIEL BATISTA CONCEICAO DOS SANTOS
hcfmusp.contributor.author-fmusphcLUIS HENRIQUE WOLFF GOWDAK
hcfmusp.contributor.author-fmusphcELIAS DAVID NETO
hcfmusp.contributor.author-fmusphcJOSE JAYME GALVAO DE LIMA
hcfmusp.contributor.author-fmusphcLUIZ APARECIDO BORTOLOTTO
hcfmusp.description.articlenumber5882
hcfmusp.description.issue18
hcfmusp.description.volume12
hcfmusp.origemWOS
hcfmusp.origem.pubmed37762822
hcfmusp.origem.scopus2-s2.0-85172776636
hcfmusp.origem.wosWOS:001071773700001
hcfmusp.publisher.cityBASELeng
hcfmusp.publisher.countrySWITZERLANDeng
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hcfmusp.scopus.lastupdate2024-05-17
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Artigos e Materiais de Revistas Científicas - FM/MCP
Artigos e Materiais de Revistas Científicas - HC/ICHC
Artigos e Materiais de Revistas Científicas - HC/InCor
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