Lymphadenectomy in early stage endometrial cancer: a critical review of the current literature

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dc.contributorSistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP
dc.contributor.authorSIUFI, Daniela Freitas dos Santos
dc.contributor.authorSIUFI NETO, Joao
dc.contributor.authorABRAO, Mauricio Simeies
dc.contributor.authorFAVERO, Giovanni
dc.date.accessioned2015-07-01T20:29:31Z
dc.date.available2015-07-01T20:29:31Z
dc.date.issued2014
dc.description.abstractTo date there has been no consensus on the exact oncological importance of systematic lymphadenectomy in early stage endometrial cancer. In this scenario, the balance between potential therapeutic benefit and procedure-related morbidity plays a central role in the indication for the procedure since the likelihood of detecting a metastatic node is relatively low. Compared with laparotomy, laparoscopic lymphadenectomy has several clearly demonstrated advantages and is an important tool to reduce morbidity. Additionally, many authors have developed less invasive methods to selectively identify patients who are at increased risk of lymph node involvement. This paper aims to review the current literature evidence and guidelines regarding the role of lymphadenectomy in patients with early stage endometrial cancer. Alternatives such as lymphatic sampling or sentinel lymph node biopsy are possible solutions but must be further investigated through more comprehensive studies.
dc.description.indexMEDLINE
dc.identifier.citationTUMORI, v.100, n.5, p.477-485, 2014
dc.identifier.doi10.1700/1660.18154
dc.identifier.eissn2038-2529
dc.identifier.issn0300-8916
dc.identifier.urihttps://observatorio.fm.usp.br/handle/OPI/9406
dc.language.isoeng
dc.publisherPENSIERO SCIENTIFICO EDITOR
dc.relation.ispartofTumori
dc.rightsrestrictedAccess
dc.rights.holderCopyright PENSIERO SCIENTIFICO EDITOR
dc.subjectearly stage
dc.subjectendometrial cancer
dc.subjectlymphadenectomy
dc.subjectoncological outcomes
dc.subject.otherparaaortic lymphadenectomy
dc.subject.otherlymph-nodes
dc.subject.otherselective lymphadenectomy
dc.subject.otherpelvic lymphadenectomy
dc.subject.otherretrospective analysis
dc.subject.otherspace involvement
dc.subject.othercorpus cancer
dc.subject.othercarcinoma
dc.subject.othersurvival
dc.subject.otheradenocarcinoma
dc.subject.wosOncology
dc.titleLymphadenectomy in early stage endometrial cancer: a critical review of the current literature
dc.typearticle
dc.type.categoryreview
dc.type.versionpublishedVersion
dspace.entity.typePublication
hcfmusp.affiliation.countryEstados Unidos
hcfmusp.affiliation.countryisous
hcfmusp.author.externalSIUFI, Daniela Freitas dos Santos:Mayo Clin, Dept Gynecol, Phoenix, AZ USA
hcfmusp.author.externalSIUFI NETO, Joao:Mayo Clin, Dept Gynecol, Phoenix, AZ USA
hcfmusp.citation.scopus6
hcfmusp.contributor.author-fmusphcMAURICIO SIMOES ABRAO
hcfmusp.contributor.author-fmusphcGIOVANNI MASTRANTONIO DI FAVERO
hcfmusp.description.beginpage477
hcfmusp.description.endpage485
hcfmusp.description.issue5
hcfmusp.description.volume100
hcfmusp.origemWOS
hcfmusp.origem.pubmed25343539
hcfmusp.origem.scopus2-s2.0-84916882563
hcfmusp.origem.wosWOS:000348335400001
hcfmusp.publisher.cityROME
hcfmusp.publisher.countryITALY
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