Polyethylene glycol fusion associated with antioxidants: A new promise in the treatment of traumatic facial paralysis

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art_SALOMONE_Polyethylene_glycol_fusion_associated_with_antioxidants_A_new_2018.PDF (640.58 KB)
Citações na Scopus
12
Tipo de produção
article
Data de publicação
2018
DOI
Scopus
Web of Science
PubMed
Título da Revista
ISSN da Revista
Título do Volume
Editora
WILEY
Autores
Citação
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK, v.40, n.7, p.1489-1497, 2018
Projetos de Pesquisa
Unidades Organizacionais
Fascículo
Resumo
Background: Recent studies in invertebrates have taught us that early cell membrane regeneration is determinant for axonal recovery and survival after trauma. Many authors obtained extraordinary results in neural regeneration using polyethylene glycol fusion protocols, which also involved microsutures and antioxidants. Methods: Sixty rats were evaluated with functional and histological protocol after facial nerve neurotmesis. Groups A and B had their stumps coapted with microsuture after 24 hours of neurotmesis and groups C and D after 72 hours. In addition to the microstructure, groups B and D used the polyethylene glycol-fusion protocol for the modulation of the Ca12. Results: At the sixth week, the latency of group D and duration of group B was lower than groups A and C (P 5.011). The axonal diameter of the groups that used polyethylene glycol-fusion was higher than those who did not use polyethylene glycol-fusion (P 001). Conclusion: Although not providing a functional improvement, polyethylene glycolfusion slowed down demyelination.
Palavras-chave
electromyography, facial nerve, facial nerve diseases, facial nerve injuries, facial paralysis, neural regeneration
URI
https://observatorio.fm.usp.br/handle/OPI/27965
Referências
  1. BAMBA R, 2018, J HAND SURG-AM, V82
  2. BENTO RF, 1985, FACIAL NERVES, P299
  3. Bittner GD, 2012, J NEUROSCI RES, V90, P967, DOI 10.1002/jnr.23023
  4. Bittner GD, 2000, NEUROSCIENTIST, V6, P88, DOI 10.1177/107385840000600207
  5. BITTNER GD, 2000, NERVE REGENERATION, P337
  6. Borin Andrei, 2006, Braz J Otorhinolaryngol, V72, P775
  7. CAJAL SRY, 1928, DEGENERATION REGENER, P1913
  8. DERIEMER SA, 1983, BRAIN RES, V272, P157, DOI 10.1016/0006-8993(83)90373-6
  9. Fishman HM, 2003, NEWS PHYSIOL SCI, V18, P115, DOI 10.1152/nips.01429.2002
  10. GILAD GM, 1983, EXP NEUROL, V81, P158, DOI 10.1016/0014-4886(83)90165-6
  11. GILAD GM, 1986, EXPT BRAIN RES S, V13, P308
  12. Hohman MH, 2014, LARYNGOSCOPE, V124, pE283, DOI 10.1002/lary.24542
  13. Hohman MH, 2014, LARYNGOSCOPE, V124, P260, DOI 10.1002/lary.24117
  14. HOY RR, 1967, SCIENCE, V156, P251, DOI 10.1126/science.156.3772.251
  15. Kim C-Yoon, 2016, Surg Neurol Int, V7, pS637, DOI 10.4103/2152-7806.190476
  16. Kim C-Yoon, 2016, Surg Neurol Int, V7, pS632, DOI 10.4103/2152-7806.190475
  17. KINDERMAN NB, 1994, EXP NEUROL, V126, P144, DOI 10.1006/exnr.1994.1051
  18. Kircher ML, 2012, NEUROSURG FOCUS, V33, DOI 10.3171/2012.7.FOCUS12196
  19. KRAUSE TL, 1994, J NEUROSCI, V14, P6638
  20. KRAUSE TL, 1990, P NATL ACAD SCI USA, V87, P1471, DOI 10.1073/pnas.87.4.1471
  21. KREUTZBERG GW, 2000, FACIAL NERVE, P67
  22. Laverty PH, 2004, J NEUROTRAUM, V21, P1767, DOI 10.1089/neu.2004.21.1767
  23. Lore AB, 1999, J NEUROSCI, V19, P2442
  24. Mehta RP, 2009, CLIN EXP OTORHINOLAR, V2, P1, DOI 10.3342/ceo.2009.2.1.1
  25. Miyake K, 1995, J CELL BIOL, V131, P1737, DOI 10.1083/jcb.131.6.1737
  26. Nepomuceno AC, 2016, ACTA CIR BRAS, V31, P542, DOI 10.1590/S0102-865020160080000007
  27. Neumann B, 2011, DEV DYNAM, V240, P1365, DOI 10.1002/dvdy.22606
  28. Nguyen MP, 2005, J NEUROSCI RES, V81, P805, DOI 10.1002/jnr.20606
  29. Nguyen QT, 2002, NAT NEUROSCI, V5, P861, DOI 10.1038/nn905
  30. Olby NJ, 2016, J VET INTERN MED, V30, P206, DOI 10.1111/jvim.13657
  31. Remenschneider AK, 2017, OTOL NEUROTOL, V38, P572, DOI 10.1097/MAO.0000000000001337
  32. Ren S, 2017, CNS NEUROSCI THER, V23, P680, DOI 10.1111/cns.12713
  33. Rovak Jason M, 2004, Semin Plast Surg, V18, P23, DOI 10.1055/s-2004-823120
  34. SALOMONE R, 2012, THESIS
  35. Salomone R, 2013, MUSCLE NERVE, V48, P423, DOI 10.1002/mus.23768
  36. Salomone R, 2012, ANN OTO RHINOL LARYN, V121, P179, DOI 10.1177/000348941212100307
  37. SCHLAEPFER WW, 1973, J CELL BIOL, V59, P456, DOI 10.1083/jcb.59.2.456
  38. Spaeth CS, 2012, J NEUROSCI RES, V90, P945, DOI 10.1002/jnr.22823
  39. Spaeth CS, 2012, J NEUROSCI RES, V90, P955, DOI 10.1002/jnr.23022
  40. Spaeth CS, 2010, J NEUROSCI, V30, P15790, DOI 10.1523/JNEUROSCI.4155-10.2010
  41. Terasaki M, 1997, J CELL BIOL, V139, P63, DOI 10.1083/jcb.139.1.63
  42. Tsao JW, 1999, J NEUROSCI, V19, P4718
  43. Vasconcelos BEC, 2001, REV CIR TRAUMAT BUCO, V1, P13
  44. Yoo S, 2004, J NEUROBIOL, V60, P137, DOI 10.1002/neu.20005

Coleções
Artigos e Materiais de Revistas Científicas - FM/MCG
Artigos e Materiais de Revistas Científicas - FM/MOF
Artigos e Materiais de Revistas Científicas - HC/ICHC
Artigos e Materiais de Revistas Científicas - LIM/02
Artigos e Materiais de Revistas Científicas - LIM/32