Higher arterial stiffness is associated with lower cognitive performance in patients with hypertension

Imagem de Miniatura
Arquivos
art_MUELA_Higher_arterial_stiffness_is_associated_with_lower_cognitive_2018.PDF (304.82 KB)
Citações na Scopus
17
Tipo de produção
article
Data de publicação
2018
DOI
Scopus
Web of Science
PubMed
Título da Revista
ISSN da Revista
Título do Volume
Editora
WILEY
Autores
MACHADO, Michel F.
Citação
JOURNAL OF CLINICAL HYPERTENSION, v.20, n.1, p.22-30, 2018
Projetos de Pesquisa
Unidades Organizacionais
Fascículo
Resumo
Cognitive impairment and elevated arterial stiffness have been described in patients with arterial hypertension, but their association has not been well studied. We evaluated the correlation of arterial stiffness and different cognitive domains in patients with hypertension compared with those with normotension. We evaluated 211 patients (69 with normotension and 142 with hypertension). Patients were age matched and distributed according to their blood pressure: normotension, hypertension stage 1, and hypertension stage 2. Cognitive function was assessed using the Mini-Mental State Examination, Montreal Cognitive Assessment, and a battery of neuropsychological evaluations that assessed six main cognitive domains. Pulse wave velocity was measured using a Complior device, and carotid properties were assessed by radiofrequency ultrasound. Central arterial pressure and augmentation index were obtained using applanation tonometry. The hypertension stage 2 group had higher arterial stiffness and worse performance either by Mini-Mental State Examination (26.8 +/- 2.1 vs 27.3 +/- 2.1 vs 28.0 +/- 2.0, P=.003) or the Montreal Cognitive Assessment test (23.4 +/- 3.5 vs 24.9 +/- 2.9 vs 25.6 +/- 3.0, P<.001). On multivariable regression analysis, augmentation index, intima-media thickness, and pulse wave velocity were the variables mainly associated with lower cognitive performance at different cognitive domains. Cognitive impairment in different domains was associated with higher arterial stiffness.
Palavras-chave
arterial stiffness, cognitive impairment, hypertension, pulse wave velocity
URI
https://observatorio.fm.usp.br/handle/OPI/26347
Referências
  1. Antelmi I, 2008, ARQ BRAS CARDIOL, V90, P413, DOI 10.1590/S0066-782X2008000600005
  2. Aprahamian I, 2010, INT PSYCHOGERIATR, V22, P64, DOI 10.1017/S1041610209991141
  3. ASMAR R, 1995, HYPERTENSION, V26, P485, DOI 10.1161/01.HYP.26.3.485
  4. Axelrod BN, 2001, ARCH CLIN NEUROPSYCH, V16, P293, DOI 10.1016/S0887-6177(00)00048-2
  5. Brucki SMD, 2003, ARQ NEURO-PSIQUIAT, V61, P777, DOI 10.1590/S0004-282X2003000500014
  6. Cameron JD, 1998, J AM COLL CARDIOL, V32, P1214, DOI 10.1016/S0735-1097(98)00411-2
  7. Cooper LL, 2016, HYPERTENSION, V67, P176, DOI 10.1161/HYPERTENSIONAHA.115.06398
  8. Davies JI, 2003, J HYPERTENS, V21, P463, DOI 10.1097/01.hjh.0000052468.40108.43
  9. Drager LF, 2005, AM J RESP CRIT CARE, V172, P613, DOI 10.1164/rccm.200503-340OC
  10. FOLSTEIN MF, 1975, J PSYCHIAT RES, V12, P189, DOI 10.1016/0022-3956(75)90026-6
  11. Franklin SS, 1997, CIRCULATION, V96, P308
  12. Hanon O, 2005, STROKE, V36, P2193, DOI 10.1161/01.STR.0000181771.82518.1c
  13. Hanon O, 2001, HYPERTENSION, V38, P1185, DOI 10.1161/hy1101.096802
  14. Kelly RP, 2001, HYPERTENSION, V37, P1429, DOI 10.1161/01.HYP.37.6.1429
  15. Lemogoum D, 2004, J HYPERTENS, V22, P511, DOI 10.1097/01.hjh.0000098265.58662.94
  16. Leung JLM, 2011, INT PSYCHOGERIATR, V23, P1569, DOI 10.1017/S1041610211000792
  17. Liao DP, 1999, HYPERTENSION, V34, P201, DOI 10.1161/01.HYP.34.2.201
  18. Malloy-Diniz LF, 2007, REV BRAS PSIQUIATR, V29, P324, DOI 10.1590/S1516-44462006005000053
  19. Marfella R, 2016, HYPERTENSION, V67, P30, DOI 10.1161/HYPERTENSIONAHA.115.06450
  20. McEniery CM, 2005, J AM COLL CARDIOL, V46, P1753, DOI 10.1016/j.jacc.2005.07.037
  21. Memoria CM, 2013, INT J GERIATR PSYCH, V28, P34, DOI 10.1002/gps.3787
  22. Miotto EC, 2010, REV BRAS PSIQUIATR, V32, P279, DOI 10.1590/S1516-44462010005000006
  23. Mitchell GF, 2011, BRAIN, V134, P3398, DOI 10.1093/brain/awr253
  24. Muela HCS, 2017, J AM HEART ASSOC, V6, DOI 10.1161/JAHA.116.004579
  25. Muiesan ML, 2013, HYPERTENSION, V61, P130, DOI 10.1161/HYPERTENSIONAHA.111.00006
  26. Nasreddine ZS, 2005, J AM GERIATR SOC, V53, P695, DOI 10.1111/j.1532-5415.2005.53221.x
  27. Obisesan TO, 2009, CLIN GERIATR MED, V25, P259, DOI 10.1016/j.cger.2009.03.002
  28. Pase MP, 2016, HYPERTENSION, V67, P513, DOI 10.1161/HYPERTENSIONAHA.115.06610
  29. Pase MP, 2010, J HYPERTENS, V28, P1724, DOI 10.1097/HJH.0b013e32833b1ee7
  30. Payne RA, 2010, HYPERTENSION, V55, P9, DOI 10.1161/HYPERTENSIONAHA.107.090464
  31. Poels MMF, 2007, STROKE, V38, P888, DOI 10.1161/01.STR.0000257998.33768.87
  32. Rabkin SW, 2012, J ALZHEIMERS DIS, V32, P541, DOI 10.3233/JAD-2012-120757
  33. ROSEN W G, 1980, Journal of Clinical Neuropsychology, V2, P135, DOI 10.1080/01688638008403788
  34. Sakurai M, 2007, J HYPERTENS, V25, P391, DOI 10.1097/HJH.0b013e3280115b7c
  35. Scuteri A, 2005, J HYPERTENS, V23, P1211, DOI 10.1097/01.hjh.0000170384.38708.b7
  36. Scuteri A, 2011, J HYPERTENS, V29, P1469, DOI 10.1097/HJH.0b013e328347cc17
  37. Shin MS, 2006, NAT PROTOC, V1, P892, DOI 10.1038/nprot.2006.115
  38. Sociedade BDH, 2010, ARQ BRAS CARDIOL, V95, P1
  39. Strauss E, 2006, COMPENDIUM NEUROPSYC, P655
  40. Tombaugh TN, 1999, ARCH CLIN NEUROPSYCH, V14, P167, DOI 10.1016/S0887-6177(97)00095-4
  41. Van Bortel LM, 2012, J HYPERTENS, V30, P445, DOI 10.1097/HJH.0b013e32834fa8b0
  42. Waldstein SR, 2005, HYPERTENSION, V45, P374, DOI 10.1161/01.HYP.0000156744.44218.74
  43. Wassertheurer S, 2010, J HUM HYPERTENS, V24, P498, DOI 10.1038/jhh.2010.27
  44. Watson NL, 2011, J GERONTOL A-BIOL, V66, P1336, DOI 10.1093/gerona/glr119
  45. World Health Organization, 2012, DEM PUBL HLTH PRIOR
  46. Yasmin, 1999, QJM-MON J ASSOC PHYS, V92, P595, DOI 10.1093/qjmed/92.10.595
  47. [Anonymous], 2013, G8 DEMENTIA SUMMIT D

Coleções
Artigos e Materiais de Revistas Científicas - FM/MNE
Artigos e Materiais de Revistas Científicas - HC/ICHC
Artigos e Materiais de Revistas Científicas - HC/InCor
Artigos e Materiais de Revistas Científicas - LIM/15
Artigos e Materiais de Revistas Científicas - LIM/26
Artigos e Materiais de Revistas Científicas - LIM/45