Doenças pulmonares císticas difusas: diagnóstico diferencial

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dc.contributorSistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP
dc.contributor.authorBALDI, Bruno Guedes
dc.contributor.authorCARVALHO, Carlos Roberto Ribeiro
dc.contributor.authorDIAS, Olivia Meira
dc.contributor.authorMARCHIORI, Edson
dc.contributor.authorHOCHHEGGER, Bruno
dc.date.accessioned2017-06-09T15:31:32Z
dc.date.available2017-06-09T15:31:32Z
dc.date.issued2017
dc.description.abstractAs doenças pulmonares císticas difusas se caracterizam pela presença de cistos envolvendo mais de um lobo pulmonar, que se originam por diversos mecanismos, incluindo dilatação dos espaços aéreos distais por obstrução, necrose das paredes das vias aéreas e destruição do parênquima. Essas doenças apresentam evolução variável. A TCAR é fundamental na avaliação dessas doenças uma vez que permite uma melhor caracterização dos cistos pulmonares, incluindo sua distribuição, tamanho, extensão e regularidade das paredes, assim como a determinação de outras lesões pulmonares e extrapulmonares associadas. Frequentemente a TCAR é suficiente para a definição etiológica dos cistos pulmonares difusos, associada a achados clínicos e laboratoriais, sem a necessidade de realização de biópsia pulmonar. O diagnóstico diferencial das doenças pulmonares císticas difusas é extenso, incluindo etiologias neoplásicas, inflamatórias e infecciosas, sendo as mais frequentes determinantes desse padrão tomográfico a histiocitose pulmonar de células de Langerhans, a linfangioleiomiomatose, a pneumonia intersticial linfocitária e a bronquiolite folicular. Novas etiologias foram incluídas como potenciais determinantes desse padrão.
dc.description.abstractDiffuse cystic lung diseases are characterized by cysts in more than one lung lobe, the cysts originating from various mechanisms, including the expansion of the distal airspaces due to airway obstruction, necrosis of the airway walls, and parenchymal destruction. The progression of these diseases is variable. One essential tool in the evaluation of these diseases is HRCT, because it improves the characterization of pulmonary cysts (including their distribution, size, and length) and the evaluation of the regularity of the cyst wall, as well as the identification of associated pulmonary and extrapulmonary lesions. When combined with clinical and laboratory findings, HRCT is often sufficient for the etiological definition of diffuse lung cysts, avoiding the need for lung biopsy. The differential diagnoses of diffuse cystic lung diseases are myriad, including neoplastic, inflammatory, and infectious etiologies. Pulmonary Langerhans cell histiocytosis, lymphangioleiomyomatosis, lymphocytic interstitial pneumonia, and follicular bronchiolitis are the most common diseases that produce this CT pattern. However, new diseases have been included as potential determinants of this pattern.
dc.description.indexMEDLINE
dc.identifier.citationJORNAL BRASILEIRO DE PNEUMOLOGIA, v.43, n.2, p.140-149, 2017
dc.identifier.doi10.1590/S1806-37562016000000341
dc.identifier.eissn1806-3756
dc.identifier.issn1806-3713
dc.identifier.urihttps://observatorio.fm.usp.br/handle/OPI/19992
dc.language.isopor
dc.language.isoeng
dc.publisherSOC BRASILEIRA PNEUMOLOGIA TISIOLOGIA
dc.relation.ispartofJornal Brasileiro de Pneumologia
dc.rightsopenAccess
dc.rights.holderCopyright SOC BRASILEIRA PNEUMOLOGIA TISIOLOGIA
dc.subjectCistos
dc.subjectDiagnóstico diferencial
dc.subjectDoenças pulmonares intersticiais
dc.subjectTomografia computadorizada por raios X
dc.subjectCysts
dc.subjectDiagnosis
dc.subjectdifferential
dc.subjectLung diseases, interstitial
dc.subjecttomography, X-ray computed
dc.subject.otherhogg-dube-syndrome
dc.subject.otherpulmonary metastases
dc.subject.otherhypersensitivity pneumonitis
dc.subject.otherinterstitial pneumonia
dc.subject.otherct findings
dc.subject.otherparacoccidioidomycosis
dc.subject.otherlymphangioleiomyomatosis
dc.subject.otherbronchiolitis
dc.subject.otheramyloidosis
dc.subject.othermanagement
dc.subject.wosRespiratory System
dc.titleDoenças pulmonares císticas difusas: diagnóstico diferencial
dc.title.alternativeDiffuse cystic lung diseases: differential diagnosis
dc.typearticle
dc.type.categoryoriginal article
dc.type.versionpublishedVersion
dspace.entity.typePublication
hcfmusp.author.externalMARCHIORI, Edson:Univ Fed Fluminense, Niteroi, RJ, Brazil; Univ Fed Rio de Janeiro, Rio De Janeiro, RJ, Brazil
hcfmusp.author.externalHOCHHEGGER, Bruno:Univ Fed Ciencias Saude Porto Alegre, Porto Alegre, RS, Brazil; Santa Casa de Misericordia Porto Alegre, Porto Alegre, RS, Brazil; Pontificia Univ Catolica Rio Grande Sul PUCRS, Escola Med, Porto Alegre, RS, Brazil
hcfmusp.citation.scopus28
hcfmusp.contributor.author-fmusphcBRUNO GUEDES BALDI
hcfmusp.contributor.author-fmusphcCARLOS ROBERTO RIBEIRO DE CARVALHO
hcfmusp.contributor.author-fmusphcOLIVIA MEIRA DIAS
hcfmusp.description.beginpage140
hcfmusp.description.endpage149
hcfmusp.description.issue2
hcfmusp.description.volume43
hcfmusp.origemWOS
hcfmusp.origem.pubmed28538782
hcfmusp.origem.scieloSCIELO:S1806-37132017000200140
hcfmusp.origem.scopus2-s2.0-85019834749
hcfmusp.origem.wosWOS:000400224600013
hcfmusp.publisher.cityBRASILIA DF
hcfmusp.publisher.countryBRAZIL
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hcfmusp.scopus.lastupdate2024-05-10
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