Psychopharmacology and psychotherapy for the treatment of adults with ADHD-a systematic review of available meta-analyses

Imagem de Miniatura
Arquivos
art_MORIYAMA_Psychopharmacology_and_psychotherapy_for_the_treatment_of_adults_2013.PDF (288.9 KB)
Citações na Scopus
47
Tipo de produção
article
Data de publicação
2013
DOI
Scopus
Web of Science
PubMed
Título da Revista
ISSN da Revista
Título do Volume
Editora
CAMBRIDGE UNIV PRESS
Autores
Citação
CNS SPECTRUMS, v.18, n.6, p.296-306, 2013
Projetos de Pesquisa
Unidades Organizacionais
Fascículo
Resumo
Objective/Introduction Attention-deficit/hyperactivity disorder (ADHD) in adult life is a prevalent condition. We systematically reviewed the literature available by searching for meta-analyses assessing pharmacological and psychosocial interventions for adults with ADHD. Methods Using wide-ranging search terms, we retrieved 191 titles from the PubMed and Cochrane databases. Two independent evaluators judged all abstracts. Only meta-analyses about the treatment of adults with ADHD were included. Information from meta-analyses found was systematically extracted by 3 independent evaluators. Results Eight meta-analyses were identified. Results from those meta-analyses suggest that stimulants are effective in decreasing ADHD symptoms on a short-term basis with a medium to large effect size (ES). Short-acting stimulants might be superior to long-acting stimulants, but no data on difference in adherence are available for the comparison of these two types of formulation. Bupropion is superior to placebo but less effective than stimulants. No conclusions about the impact of psychosocial interventions can be drawn based on meta-analyses so far. Discussion The efficacy of stimulants in reducing ADHD symptoms for adults is well documented in meta-analyses, but there is a concerning lack of meta-analysis about other treatment interventions. Conclusion The available meta-analytic literature does not cover questions of essential clinical relevance for adults with ADHD.
Palavras-chave
ADHD, adults, inattention, treatment
URI
https://observatorio.fm.usp.br/handle/OPI/4205
Referências
  1. Wolraich M, 2011, PEDIATRICS, V128, P1007, DOI 10.1542/peds.2011-2654
  2. [Anonymous], 2011, CAN ADHD PRACT GUID
  3. Bjornstad G, 2005, COCHRANE DB SYST REV
  4. Castells X, 2011, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD007813.pub2
  5. Cheng JYW, 2007, PSYCHOPHARMACOLOGY, V194, P197, DOI 10.1007/s00213-007-0840-x
  6. Connor DF, 1999, J AM ACAD CHILD PSY, V38, P1551, DOI 10.1097/00004583-199912000-00017
  7. Ebert D., 2003, Nervenarzt, V74, P939
  8. Fabiano GA, 2009, CLIN PSYCHOL REV, V29, P129, DOI 10.1016/j.cpr.2008.11.001
  9. Faraone Stephen V, 2005, J Atten Disord, V9, P384, DOI 10.1177/1087054705281478
  10. Faraone Stephen V, 2006, MedGenMed, V8, P4
  11. Faraone SV, 2004, J CLIN PSYCHOPHARM, V24, P24, DOI 10.1097/01.jcp.0000108984.11879.95
  12. Faraone S V, 2002, J Atten Disord, V6, P69, DOI 10.1177/108705470200600203
  13. Faraone SV, 2002, J CLIN PSYCHOPHARM, V22, P468, DOI 10.1097/01.jcp.0000033401.43191.26
  14. Faraone SV, 2006, PSYCHOL MED, V36, P159, DOI 10.1017/S003329170500471X
  15. Faraone Stephen V, 2009, P T, V34, P678
  16. Faraone SV, 2010, J CLIN PSYCHIAT, V71, P754, DOI [10.4088/JCP.08m04902pur, 10.4088/JCP08m04902pur]
  17. Faraone SV, 2010, EUR CHILD ADOLES PSY, V19, P353, DOI 10.1007/s00787-009-0054-3
  18. Fayyad J, 2007, BRIT J PSYCHIAT, V190, P402, DOI 10.1192/bjp.bp.106.034389
  19. Hanwella R, 2011, BMC PSYCHIATRY, V11, DOI 10.1186/1471-244X-11-176
  20. Hazell PL, 2011, J ATTEN DISORD, V15, P674, DOI 10.1177/1087054710379737
  21. Kessler RC, 2006, AM J PSYCHIAT, V163, P716, DOI 10.1176/appi.ajp.163.4.716
  22. Klassen A, 1999, CAN J PSYCHIAT, V44, P1007
  23. Lawson KA, 2012, CLIN THER, V34, pe4
  24. Lawson KA, 2012, CLIN THER, V34, P944, DOI 10.1016/j.clinthera.2012.02.021
  25. Linderkamp F, 2011, VERHALTENSTHERAPIE, V21, P229, DOI 10.1159/000332429
  26. Lopez-Munoz F, 2008, EUR CHILD ADOLES PSY, V17, P381, DOI 10.1007/s00787-008-0680-1
  27. Majewicz-Hefley Amy, 2007, J Atten Disord, V10, P239, DOI 10.1177/1087054706289934
  28. Maneeton N, 2011, PSYCHIAT CLIN NEUROS, V65, P611, DOI 10.1111/j.1440-1819.2011.02264.x
  29. Marcus SC, 2005, ARCH PEDIAT ADOL MED, V159, P572, DOI 10.1001/archpedi.159.6.572
  30. Meszaros A, 2009, INT J NEUROPSYCHOPH, V12, P1137, DOI 10.1017/S1461145709990198
  31. Michielsen M, 2012, BR J PSYCHIAT
  32. National Institute of Health and Clinical Excelence (NICE), 2008, ATT DEF HYP DIS DIAG
  33. Nutt DJ, 2007, J PSYCHOPHARMACOL, V21, P10, DOI 10.1177/0269881106073219
  34. Peterson K, 2008, PSYCHOPHARMACOLOGY, V197, P1, DOI 10.1007/s00213-007-0996-4
  35. Pliszka S, 2007, J AM ACAD CHILD PSY, V46, P894, DOI 10.1097/chi.0b013e318054e724
  36. Polanczyk G, 2007, AM J PSYCHIAT, V164, P942, DOI 10.1176/appi.ajp.164.6.942
  37. Safren SA, 2010, JAMA-J AM MED ASSOC, V304, P875, DOI 10.1001/jama.2010.1192
  38. Schachter HA, 2001, CAN MED ASSOC J, V165, P1475
  39. Seixas M, 2012, J PSYCHOPHARMACOL, V26, P753, DOI 10.1177/0269881111412095
  40. Simon V, 2009, BRIT J PSYCHIAT, V194, P204, DOI 10.1192/bjp.bp.107.048827
  41. Storebo OJ, 2011, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD008223.pub2
  42. Van der Oord S, 2008, CLIN PSYCHOL REV, V28, P783, DOI 10.1016/j.cpr.2007.10.007
  43. Verbeeck W, 2009, ADV THER, V26, P170, DOI 10.1007/s12325-009-0008-7
  44. Weiss MD, 2006, J CLIN PSYCHIAT, V67, P38
  45. Winterstein AG, 2008, ANN PHARMACOTHER, V42, P24, DOI 10.1345/aph.1K143
  46. Zwi M, 2011, COCHRANE DB SYST REV, DOI 10.1002/14651858.CD003018.pub3

Coleções
Artigos e Materiais de Revistas Científicas - FM/MPS
Artigos e Materiais de Revistas Científicas - HC/IPq
Artigos e Materiais de Revistas Científicas - LIM/21