Group cognitive-behavioral therapy versus selective serotonin reuptake inhibitors for obsessive-compulsive disorder: A practical clinical trial
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Citações na Scopus
59
Tipo de produção
article
Data de publicação
2012
Título da Revista
ISSN da Revista
Título do Volume
Editora
PERGAMON-ELSEVIER SCIENCE LTD
Autores
MALAVAZZI, Dante Marino
FOSSALUZA, Victor
MORELLI, Dawn
Citação
JOURNAL OF ANXIETY DISORDERS, v.26, n.1, p.25-31, 2012
Resumo
Clinical effectiveness of group cognitive-behavioral therapy (GCBT) versus fluoxetine in obsessive-compulsive disorder outpatients that could present additional psychiatric comorbidities was assessed. Patients (18-65 years; baseline Yale-Brown Obsessive-Compulsive-Scale [Y-BOCS] scores >= 16; potentially presenting additional psychiatric comorbidities) were sequentially allocated for treatment with GCBT (n = 70) or fluoxetine (n = 88). Mean Y-BOCS scores decreased by 23.13% in the GCBT and 21.54% in the SSRI groups (p = 0.875). Patients presented a mean of 2.7 psychiatric comorbidities. and 81.4% showed at least one additional disorder. A reduction of at least 35% in baseline Y-BOCS scores and CGI ratings of 1 (much better) or 2 (better) was achieved by 33.3% of GCBT patients and 27.7% in the SSRI group (p = 0.463). The Y-BOCS reduction was significantly lower in patients with one or more psychiatric comorbidities (21.15%, and 18.73%, respectively) than in those with pure OCD (34.62%; p = 0.034). Being male, having comorbidity of Major Depression, Social Phobia, or Dysthymia predicted a worse response to both treatments. Response rates to both treatments were similar and lower than reported in the literature, probably due to the broad inclusion criteria and the resulting sample more similar to the real world population.
Palavras-chave
Obsessive-compulsive disorder, Practical clinical trial, Group cognitive-behavioral therapy, Selective serotonin reuptake inhibitors
Referências
- Abramowitz JS, 2003, J CONSULT CLIN PSYCH, V71, P1049, DOI 10.1037/0022-006X.71.6.1049
- Abramowitz JS, 2000, BEHAV THER, V31, P517, DOI 10.1016/S0005-7894(00)80028-3
- Anderson RA, 2007, BEHAV RES THER, V45, P123, DOI 10.1016/j.brat.2006.01.016
- Bandelow B, 2008, WORLD J BIOL PSYCHIA, V9, P248, DOI 10.1080/15622970802465807
- Catania A. C., 1998, LEARNING
- Choi YJ, 2009, J AM ACAD NURSE PRAC, V21, P207, DOI 10.1111/j.1745-7599.2009.00408.x
- Cordioli A., 2002, THESIS U FEDERAL RIO
- Cordioli AV, 2003, PSYCHOTHER PSYCHOSOM, V72, P211, DOI 10.1159/000070785
- COTTRAUX J, 1990, INT CLIN PSYCHOPHARM, V5, P17, DOI 10.1097/00004850-199001000-00002
- First M.B., 1995, STRUCTURED CLIN INTE
- Foa EB, 2005, AM J PSYCHIAT, V162, P151, DOI 10.1176/appi.ajp.162.1.151
- Fossaluza V, 2009, CLINICS, V64, P511, DOI 10.1590/S1807-59322009000600005
- GOODMAN WK, 1989, ARCH GEN PSYCHIAT, V46, P1006
- Guy W, 1976, ECDEU ASSESSMENT MAN
- Holander E., 2002, J CLIN PSYCHIAT, V63, P20
- INSEL TR, 1992, ARCH GEN PSYCHIAT, V49, P739
- Johnsen E, 2008, BMC PSYCHIATRY, V8, DOI 10.1186/1471-244X-8-31
- Keeley ML, 2008, CLIN PSYCHOL REV, V28, P118, DOI 10.1016/j.cpr.2007.04.003
- McLean PD, 2001, J CONSULT CLIN PSYCH, V69, P205, DOI 10.1037//0022-006X.69.2.205
- Miguel EC, 2008, REV BRAS PSIQUIATR, V30, P185
- PICCINELLI M, 1995, BRIT J PSYCHIAT, V166, P424, DOI 10.1192/bjp.166.4.424
- Piggoy T. A., 1999, J CLIN PSYCHIAT, V60, P101
- Rush AJ, 2004, CONTROL CLIN TRIALS, V25, P119, DOI 10.1016/S0197-2456(03)00112-0
- Seligman M.E.P., 1975, HELPLESSNESS DEPRESS
- Shavitt Roseli G, 2006, Compr Psychiatry, V47, P276, DOI 10.1016/j.comppsych.2005.09.001
- Sotres-Bayon F, 2006, BIOL PSYCHIAT, V60, P329, DOI 10.1016/j.biopsych.2005.10.012
- Sousa MB, 2006, J CLIN PSYCHIAT, V67, P1133
- Steketee G, 1999, PSYCHIAT RES, V89, P229, DOI 10.1016/S0165-1781(99)00104-3
- Storch EA, 2008, J ANXIETY DISORD, V22, P1146, DOI 10.1016/j.janxdis.2007.12.001
- Tolin DF, 2004, J CLIN PSYCHIAT, V65, P922
- Torresan RC, 2009, COMPR PSYCHIAT, V50, P63, DOI 10.1016/j.comppsych.2008.05.005
- Tundo A, 2007, J CLIN PSYCHIAT, V68, P1552
- Tunis SR, 2003, JAMA-J AM MED ASSOC, V290, P1624, DOI 10.1001/jama.290.12.1624
- Whittal ML, 2005, BEHAV RES THER, V43, P1559, DOI 10.1016/j.brat.2004.11.012
- Zitterl W, 2000, PSYCHOPATHOLOGY, V33, P75, DOI 10.1159/000029124
- Zohar J, 1992, Clin Neuropharmacol, V15 Suppl 1 Pt A, p257A