Pancreatic endosonographic findings and clinical correlation in Crohn's disease

Página do item simplificado
dc.contributorSistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP
dc.contributor.authorMALLUTA, Everson Fernando
dc.contributor.authorMALUF-FILHO, Fauze
dc.contributor.authorLEITE, Andre Zonetti de Arruda
dc.contributor.authorORTIZ-AGOSTINHO, Carmen Lucia
dc.contributor.authorNISHITOKUKADO, Lecia
dc.contributor.authorANDRADE, Adriana Ribas
dc.contributor.authorLORDELLO, Maria Laura Lacava
dc.contributor.authorSANTOS, Fabiana Maria dos
dc.contributor.authorSIPAHI, Aytan Miranda
dc.date.accessioned2019-08-20T14:53:13Z
dc.date.available2019-08-20T14:53:13Z
dc.date.issued2019
dc.description.abstractOBJECTIVES: We aimed to evaluate the incidence of pancreatic alterations in Crohn's disease using endoscopic ultrasound (EUS) and to correlate the number of alterations with current clinical data. METHODS: Patients diagnosed with Crohn's disease (n= 51) were examined using EUS, and 11 variables were analyzed. A control group consisted of patients with no history of pancreatic disease or Crohn's disease. Patients presenting with three or more alterations underwent magnetic resonance imaging (MRI). Pancreatic function was determined using a fecal elastase assay. RESULTS: Two of the 51 patients (3.9%) presented with four EUS alterations, 3 (5.9%) presented with three, 11 (21.5%) presented with two, and 13 (25.5%) presented with one; in the control group, only 16% presented with one EUS alteration (p< 0.001). Parenchymal abnormalities accounted for 39 of the EUS findings, and ductal abnormalities accounted for 11. Pancreatic lesions were not detected by MRI. Low fecal elastase levels were observed in 4 patients, none of whom presented with significant pancreatic alterations after undergoing EUS. Ileal involvement was predictive of the number of EUS alterations. CONCLUSION: A higher incidence of pancreatic abnormalities was found in patients with Crohn's disease than in individuals in the control group. The majority of these abnormalities are related to parenchymal alterations. In this group of patients, future studies should be conducted to determine whether such morphological abnormalities could evolve to induce exocrine or endocrine pancreatic insufficiency and, if so, identify the risk factors and determine which patients should undergo EUS.eng
dc.description.indexMEDLINEeng
dc.identifier.citationCLINICS, v.74, article ID e853, 6p, 2019
dc.identifier.doi10.6061/clinics/2019/e853
dc.identifier.eissn1980-5322
dc.identifier.issn1807-5932
dc.identifier.urihttps://observatorio.fm.usp.br/handle/OPI/33256
dc.language.isoeng
dc.publisherHOSPITAL CLINICAS, UNIV SAO PAULOeng
dc.relation.ispartofClinics
dc.rightsopenAccesseng
dc.rights.holderCopyright HOSPITAL CLINICAS, UNIV SAO PAULOeng
dc.subjectCrohn's Diseaseeng
dc.subjectPancreatitiseng
dc.subjectPancreatic Exocrine Insufficiencyeng
dc.subjectEndosonographyeng
dc.subjectCholangiopancreatographyeng
dc.subject.otherinflammatory-bowel-diseaseeng
dc.subject.otherendoscopic retrograde cholangiopancreatographyeng
dc.subject.othersecretin-pancreozymin testeng
dc.subject.otherfecal elastase-1eng
dc.subject.otherfollow-upeng
dc.subject.otherautoimmune pancreatitiseng
dc.subject.otherregional enteritiseng
dc.subject.otherdiagnosiseng
dc.subject.otherultrasonographyeng
dc.subject.otherultrasoundeng
dc.subject.wosMedicine, General & Internaleng
dc.titlePancreatic endosonographic findings and clinical correlation in Crohn's diseaseeng
dc.typearticleeng
dc.type.categoryoriginal articleeng
dc.type.versionpublishedVersioneng
dspace.entity.typePublication
hcfmusp.author.externalMALLUTA, Everson Fernando:Univ Sao Paulo, Hosp Clin HCFMUSP, Fac Med, Lab Gastroenterol Clin & Expt, Sao Paulo, SP, Brazil
hcfmusp.author.externalNISHITOKUKADO, Lecia:Univ Sao Paulo, Hosp Clin HCFMUSP, Fac Med, Lab Gastroenterol Clin & Expt, Sao Paulo, SP, Brazil
hcfmusp.author.externalLORDELLO, Maria Laura Lacava:Univ Sao Paulo, Hosp Clin HCFMUSP, Fac Med, Lab Gastroenterol Clin & Expt, Sao Paulo, SP, Brazil
hcfmusp.citation.scopus4
hcfmusp.contributor.author-fmusphcFAUZE MALUF FILHO
hcfmusp.contributor.author-fmusphcANDRE ZONETTI DE ARRUDA LEITE
hcfmusp.contributor.author-fmusphcCARMEN LUCIA ORTIZ AGOSTINHO
hcfmusp.contributor.author-fmusphcADRIANA RIBAS ANDRADE
hcfmusp.contributor.author-fmusphcFABIANA MARIA DOS SANTOS
hcfmusp.contributor.author-fmusphcAYTAN MIRANDA SIPAHI
hcfmusp.description.articlenumbere853
hcfmusp.description.volume74
hcfmusp.origemWOS
hcfmusp.origem.pubmed31166473
hcfmusp.origem.scieloSCIELO:S1807-59322019000100232
hcfmusp.origem.scopus2-s2.0-85067504348
hcfmusp.origem.wosWOS:000470771600001
hcfmusp.publisher.citySAO PAULOeng
hcfmusp.publisher.countryBRAZILeng
hcfmusp.relation.referenceAmann ST, 1996, PANCREAS, V13, P226, DOI 10.1097/00006676-199610000-00002eng
hcfmusp.relation.referenceANGELINI G, 1988, INT J PANCREATOL, V3, P185eng
hcfmusp.relation.referenceAXON ATR, 1979, CLIN RADIOL, V30, P179, DOI 10.1016/S0009-9260(79)80146-4eng
hcfmusp.relation.referenceBALL WP, 1950, ARCH PATHOL, V50, P347eng
hcfmusp.relation.referenceBarthet M, 1999, AM J GASTROENTEROL, V94, P2141eng
hcfmusp.relation.referenceBarthet M, 2006, PANCREATOLOGY, V6, P464, DOI 10.1159/000094564eng
hcfmusp.relation.referenceBokemeyer B, 2002, Z GASTROENTEROL, V40, P5, DOI 10.1055/s-2002-19636eng
hcfmusp.relation.referenceBor Renata, 2014, Orv Hetil, V155, P1000, DOI 10.1556/OH.2014.29936eng
hcfmusp.relation.referenceBUSCAIL L, 1995, PANCREAS, V10, P251, DOI 10.1097/00006676-199504000-00006eng
hcfmusp.relation.referenceCatalano MF, 2007, J GASTROENTEROL, V42, P78, DOI 10.1007/s00535-006-1915-xeng
hcfmusp.relation.referenceCatalano MF, 1998, GASTROINTEST ENDOSC, V48, P11, DOI 10.1016/S0016-5107(98)70122-1eng
hcfmusp.relation.referenceCHAPIN LE, 1956, GASTROENTEROLOGY, V30, P404eng
hcfmusp.relation.referenceChowdhury RS, 2003, ALIMENT PHARM THERAP, V17, P733, DOI 10.1046/j.0269-2813.2003.01495.xeng
hcfmusp.relation.referenceDOBRILLA G, 1972, GASTROENTEROLOGY, V63, P713eng
hcfmusp.relation.referenceEctors N, 1997, GUT, V41, P263, DOI 10.1136/gut.41.2.263eng
hcfmusp.relation.referenceEISNER TD, 1993, AM J GASTROENTEROL, V88, P583eng
hcfmusp.relation.referenceEtemad B, 2001, GASTROENTEROLOGY, V120, P682, DOI 10.1053/gast.2001.22586eng
hcfmusp.relation.referenceFarrell JJ, 2004, GASTROINTEST ENDOSC, V60, P927, DOI 10.1016/S0016-5107(04)02230-8eng
hcfmusp.relation.referenceFinkelberg DL, 2006, NEW ENGL J MED, V355, P2670, DOI 10.1056/NEJMra061200eng
hcfmusp.relation.referenceGlasbrenner B, 2002, EUR J GASTROEN HEPAT, V14, P935, DOI 10.1097/00042737-200209000-00003eng
hcfmusp.relation.referenceGSCHWANTLER M, 1995, GASTROENTEROLOGY, V108, P1246, DOI 10.1016/0016-5085(95)90226-0eng
hcfmusp.relation.referenceGullo L, 1999, DIGEST DIS SCI, V44, P210, DOI 10.1023/A:1026691209094eng
hcfmusp.relation.referenceHardt Philip D, 2002, Pancreas, V25, pe6, DOI 10.1097/00006676-200207000-00004eng
hcfmusp.relation.referenceHawes RH, 1999, GASTROINTEST ENDOSC, V49, pS74, DOI 10.1016/S0016-5107(99)70531-6eng
hcfmusp.relation.referenceHEGNHOJ J, 1990, GUT, V31, P1076, DOI 10.1136/gut.31.9.1076eng
hcfmusp.relation.referenceHeikius B, 1996, SCAND J GASTROENTERO, V31, P517, DOI 10.3109/00365529609006775eng
hcfmusp.relation.referenceHoki N, 2009, J GASTROENTEROL, V44, P154, DOI 10.1007/s00535-008-2294-2eng
hcfmusp.relation.referenceHollerbach S, 2001, ENDOSCOPY, V33, P824, DOI 10.1055/s-2001-17337eng
hcfmusp.relation.referenceIrisawa A, 2007, J GASTROENTEROL, V42, P90, DOI 10.1007/s00535-006-1916-9eng
hcfmusp.relation.referenceJung JG, 2015, PANCREATOLOGY, V15, P259, DOI 10.1016/j.pan.2015.03.011eng
hcfmusp.relation.referenceKahl S, 2002, GASTROINTEST ENDOSC, V55, P507, DOI 10.1067/mge.2002.122610eng
hcfmusp.relation.referenceKeim Volker, 2003, Clin Lab, V49, P209eng
hcfmusp.relation.referenceKim KP, 2006, WORLD J GASTROENTERO, V12, P2487, DOI 10.3748/wjg.v12.i16.2487eng
hcfmusp.relation.referenceKoutroubakis IE, 2005, DIGEST DIS SCI, V50, P2330, DOI 10.1007/s10620-005-3056-0eng
hcfmusp.relation.referenceLankisch Paul G, 2004, Curr Gastroenterol Rep, V6, P126, DOI 10.1007/s11894-004-0039-9eng
hcfmusp.relation.referenceLankisch PG, 2003, DIGEST LIVER DIS, V35, P131, DOI 10.1016/S1590-8658(03)00019-7eng
hcfmusp.relation.referenceLankisch PG, 1998, GUT, V42, P551, DOI 10.1136/gut.42.4.551eng
hcfmusp.relation.referenceLankisch PG, 1996, PANCREAS, V12, P149, DOI 10.1097/00006676-199603000-00007eng
hcfmusp.relation.referenceLINDSTROM E, 1990, ACTA CHIR SCAND, V156, P451eng
hcfmusp.relation.referenceLoser C, 1996, GUT, V39, P580, DOI 10.1136/gut.39.4.580eng
hcfmusp.relation.referenceMaartense S, 2004, DIGEST LIVER DIS, V36, P61, DOI 10.1016/j.dld.2003.06.004eng
hcfmusp.relation.referenceMALFERTHEINER P, 1986, HEPATO-GASTROENTEROL, V33, P110eng
hcfmusp.relation.referenceMartinelli M, 2015, DIGEST LIVER DIS, V47, P384, DOI 10.1016/j.dld.2015.01.155eng
hcfmusp.relation.referenceMEE AS, 1985, GUT, V26, P1257, DOI 10.1136/gut.26.11.1257eng
hcfmusp.relation.referenceMiyakawa H, 2007, J GASTROENTEROL, V42, P85, DOI 10.1007/s00535-006-1935-6eng
hcfmusp.relation.referenceMoon Sung-Hoon, 2013, Gastrointest Endosc Clin N Am, V23, P893, DOI 10.1016/j.giec.2013.06.005eng
hcfmusp.relation.referenceMorselli-Labate AM, 2009, J GASTROEN HEPATOL, V24, P15, DOI 10.1111/j.1440-1746.2008.05676.xeng
hcfmusp.relation.referenceNATTERMANN C, 1993, ENDOSCOPY, V25, P565, DOI 10.1055/s-2007-1010406eng
hcfmusp.relation.referenceNIEMELA S, 1989, HEPATO-GASTROENTEROL, V36, P175eng
hcfmusp.relation.referenceOishi Y, 2004, J GASTROENTEROL, V39, P26, DOI 10.1007/s00535-003-1241-5eng
hcfmusp.relation.referenceOwiang C., 1999, TXB GASTROENTEROLOGY, V2, P2151eng
hcfmusp.relation.referencePapp M, 2015, J CROHNS COLITIS, V9, P659, DOI 10.1093/ecco-jcc/jjv087eng
hcfmusp.relation.referencePavlidis P, 2012, CLIN DEV IMMUNOL, DOI 10.1155/2012/640835eng
hcfmusp.relation.referencePIONTEK M, 1990, J CLIN GASTROENTEROL, V12, P491eng
hcfmusp.relation.referencePitchumoni CS, 2013, J CLIN GASTROENTEROL, V47, P469, DOI 10.1097/MCG.0b013e31828a7099eng
hcfmusp.relation.referencePitchumoni CS, 2010, J CLIN GASTROENTEROL, V44, P246, DOI 10.1097/MCG.0b013e3181cadbe1eng
hcfmusp.relation.referenceRaimondo Massimo, 2004, JOP, V5, P1eng
hcfmusp.relation.referenceRasmussen HH, 1999, SCAND J GASTROENTERO, V34, P199eng
hcfmusp.relation.referenceRavi K, 2009, INFLAMM BOWEL DIS, V15, P1326, DOI 10.1002/ibd.20898eng
hcfmusp.relation.referenceSahai AV, 1998, GASTROINTEST ENDOSC, V48, P18, DOI 10.1016/S0016-5107(98)70123-3eng
hcfmusp.relation.referenceSandborn WJ, 2002, GASTROENTEROLOGY, V122, P512, DOI 10.1053/gast.2002.31072eng
hcfmusp.relation.referenceSeibold F, 1996, J CLIN GASTROENTEROL, V22, P202, DOI 10.1097/00004836-199604000-00010eng
hcfmusp.relation.referenceSEYRIG JA, 1985, DIGEST DIS SCI, V30, P1121, DOI 10.1007/BF01314044eng
hcfmusp.relation.referenceSrinath AI, 2016, INFLAMM BOWEL DIS, V22, P465, DOI 10.1097/MIB.0000000000000611eng
hcfmusp.relation.referenceSTOCKER W, 1987, SCAND J GASTROENTERO, V22, P41, DOI 10.3109/00365528709089774eng
hcfmusp.relation.referenceTrikudanathan G, 2011, J CLIN GASTROENTEROL, V45, P83, DOI 10.1097/MCG.0b013e3181d9f935eng
hcfmusp.relation.referenceVirk R, 2014, MODERN PATHOL, V27, P454, DOI 10.1038/modpathol.2013.121eng
hcfmusp.relation.referenceWIERSEMA MJ, 1993, ENDOSCOPY, V25, P555, DOI 10.1055/s-2007-1010405eng
hcfmusp.relation.referenceYOSHIDA K, 1995, DIGEST DIS SCI, V40, P1561, DOI 10.1007/BF02285209eng
hcfmusp.scopus.lastupdate2024-05-10
relation.isAuthorOfPublicationdd9483d6-20a5-444b-a942-51323dcebfc5
relation.isAuthorOfPublication41b71c3f-3d4c-45b9-a1aa-38a248a090f3
relation.isAuthorOfPublication99036f7a-c516-4eb7-8ef3-8c9440b1f8d8
relation.isAuthorOfPublication563a029f-d8f5-433d-b803-8650da651d59
relation.isAuthorOfPublicationcd19db09-d94f-4e22-98e8-fb2332cf3060
relation.isAuthorOfPublication5f9970e2-178f-4dae-b809-643a75d620c6
relation.isAuthorOfPublication.latestForDiscoverydd9483d6-20a5-444b-a942-51323dcebfc5
Arquivos
Pacote Original
Agora exibindo 1 - 1 de 1
Imagem de Miniatura
Nome:
art_MALLUTA_Pancreatic_endosonographic_findings_and_clinical_correlation_in_Crohns_2019.PDF
Tamanho:
344.88 KB
Formato:
Adobe Portable Document Format
Descrição:
publishedVersion (English)
Baixar
Coleções
Artigos e Materiais de Revistas Científicas - HC/ICHC
Artigos e Materiais de Revistas Científicas - HC/ICESP
Artigos e Materiais de Revistas Científicas - HC/ICr
Artigos e Materiais de Revistas Científicas - LIM/07
Artigos e Materiais de Revistas Científicas - LIM/37