Leishmania infection in blood donors: A new challenge in leishmaniasis transmission?

Página do item simplificado
dc.contributorSistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP
dc.contributor.authorFRANCA, Adriana de Oliveira
dc.contributor.authorPOMPILIO, Mauricio Antonio
dc.contributor.authorPONTES, Elenir Rose Jardim Cury
dc.contributor.authorOLIVEIRA, Marcia Pereira de
dc.contributor.authorPEREIRA, Luiza Oliveira Ramos
dc.contributor.authorLIMA, Rosimar Baptista
dc.contributor.authorGOTO, Hiro
dc.contributor.authorSANCHEZ, Maria Carmen Arroyo
dc.contributor.authorFUJIMORI, Mahyumi
dc.contributor.authorLIMA-JUNIORS, Manoel Sebastiao da Costa
dc.contributor.authorMATOS, Maria de Fatima Cepa
dc.contributor.authorDORVAL, Maria Elizabeth Moraes Cavalheiros
dc.date.accessioned2018-09-13T15:26:02Z
dc.date.available2018-09-13T15:26:02Z
dc.date.issued2018
dc.description.abstractTransfusion-transmitted leishmaniasis has been a concern in regions endemic for the disease. Whether immediate or delayed, the risks posed by this mode of transmission call for careful assessment. The purpose of this study was to detect Leishmania infection in blood donors living in an endemic area and to investigate progression to the disease in these individuals. Immunofluorescent antibody test, enzyme-linked immunosorbent assay, leishmaniasis rapid test, and the polymerase chain reaction were applied to 430 donors in an initial evaluation. Of those donors with at least one positive test, 50 were reevaluated four years later by the same methods, as were 25 controls who had been negative on the same tests. In the first evaluation, Leishmania infection was detected in 41.4% (95% CI: 36.7-46.1) of donors (n = 430). None of the 75 reevaluated individuals had developed the disease, but retesting revealed positivity in at least one test in 36.0% (95% CI: 25.1-46.9) of donors. Of the 50 initially testing positive, 50% remained so on retesting. Of the 25 initially negative controls, two tested positive in the subsequent evaluation. The severity of the parasitosis and the risk of transfusion transmission warrant investigation of the potential inclusion of methods for Leishmania detection into blood banks for effective screening of infected donors.
dc.description.indexMEDLINE
dc.description.sponsorshipFundacao de Apoio ao Desenvolvimento do Ensino, Ciencia e Tecnologia do Estado de Mato Grosso do Sul (Fundect) [0191/12, SIAFEM:020919, 23/200.686/2012, 114/2014, SIAFEM:023670, 23/200.262/2014]
dc.identifier.citationPLOS ONE, v.13, n.6, article ID e0198199, 13p, 2018
dc.identifier.doi10.1371/journal.pone.0198199
dc.identifier.issn1932-6203
dc.identifier.urihttps://observatorio.fm.usp.br/handle/OPI/28207
dc.language.isoeng
dc.publisherPUBLIC LIBRARY SCIENCE
dc.relation.ispartofPlos One
dc.rightsopenAccess
dc.rights.holderCopyright PUBLIC LIBRARY SCIENCE
dc.subject.otherasymptomatic visceral leishmaniasis
dc.subject.otheramerican tegumentary leishmaniasis
dc.subject.otherendemic area
dc.subject.otherkala-azar
dc.subject.otherdonovani infection
dc.subject.othernortheastern brazil
dc.subject.otherinfantum infection
dc.subject.otherdiagnostic methods
dc.subject.otherperipheral-blood
dc.subject.otherbalearic-islands
dc.subject.wosMultidisciplinary Sciences
dc.titleLeishmania infection in blood donors: A new challenge in leishmaniasis transmission?
dc.typearticle
dc.type.categoryoriginal article
dc.type.versionpublishedVersion
dspace.entity.typePublication
hcfmusp.affiliation.countryEstados Unidos
hcfmusp.affiliation.countryisous
hcfmusp.author.externalFRANCA, Adriana de Oliveira:Univ Fed Mato Grosso do Sul, Grad Program Infect & Parasit Dis, Lab Clin Parasitol, Campo Grande, MS, Brazil
hcfmusp.author.externalPOMPILIO, Mauricio Antonio:Univ Fed Mato Grosso do Sul, Helio Mandetta Sch Med, Campo Grande, MS USA
hcfmusp.author.externalPONTES, Elenir Rose Jardim Cury:Univ Fed Mato Grosso do Sul, Grad Program Infect & Parasit Dis, Campo Grande, MS USA
hcfmusp.author.externalOLIVEIRA, Marcia Pereira de:Inst Oswaldo Cruz, Interdisciplinary Lab Med Res LIPMed, Rio De Janeiro, RJ, Brazil
hcfmusp.author.externalPEREIRA, Luiza Oliveira Ramos:Inst Oswaldo Cruz, Interdisciplinary Lab Med Res LIPMed, Rio De Janeiro, RJ, Brazil
hcfmusp.author.externalLIMA, Rosimar Baptista:Inst Oswaldo Cruz, Interdisciplinary Lab Med Res LIPMed, Rio De Janeiro, RJ, Brazil
hcfmusp.author.externalLIMA-JUNIORS, Manoel Sebastiao da Costa:Fundacao Oswaldo Cruz, Ageu Magalhaes Res Ctr CPqAM, Lab Immunopathol & Mol Biol, Recife, PE, Brazil
hcfmusp.author.externalMATOS, Maria de Fatima Cepa:Univ Fed Mato Grosso do Sul, Lab Mol Biol & Cell Culture, Campo Grande, MS, Brazil
hcfmusp.author.externalDORVAL, Maria Elizabeth Moraes Cavalheiros:Univ Fed Mato Grosso do Sul, Grad Program Infect & Parasit Dis, Lab Clin Parasitol, Campo Grande, MS, Brazil
hcfmusp.citation.scopus18
hcfmusp.contributor.author-fmusphcHIRO GOTO
hcfmusp.contributor.author-fmusphcMARIA CARMEN ARROYO SANCHEZ
hcfmusp.contributor.author-fmusphcMAHYUMI FUJIMORI
hcfmusp.description.articlenumbere0198199
hcfmusp.description.issue6
hcfmusp.description.volume13
hcfmusp.origemWOS
hcfmusp.origem.pubmed29902188
hcfmusp.origem.scopus2-s2.0-85057257368
hcfmusp.origem.wosWOS:000435424900015
hcfmusp.publisher.citySAN FRANCISCO
hcfmusp.publisher.countryUSA
hcfmusp.relation.referenceBarao SC, 2007, AM J TROP MED HYG, V77, P1051
hcfmusp.relation.referenceBraga LD, 2015, REV SOC BRAS MED TRO, V48, P622, DOI 10.1590/0037-8682-0043-2015
hcfmusp.relation.referenceBURNS JM, 1993, P NATL ACAD SCI USA, V90, P775, DOI 10.1073/pnas.90.2.775
hcfmusp.relation.referenceCaldas A J, 2001, Rev Soc Bras Med Trop, V34, P445, DOI 10.1590/S0037-86822001000500007
hcfmusp.relation.referenceCanavate C, 2011, AM J TROP MED HYG, V84, P102, DOI 10.4269/ajtmh.2011.10-0229
hcfmusp.relation.referenceCardo LJ, 2006, TRANSFUSION, V46, P1641, DOI 10.1111/j.1537-2995.2006.00941.x
hcfmusp.relation.referenceCardo LJ, 2005, TRANSFUSION, V45, p30A
hcfmusp.relation.referenceClemente WT, 2014, AM J TRANSPLANT, V14, P96, DOI 10.1111/ajt.12521
hcfmusp.relation.referenceCosta CHN, 2002, AM J TROP MED HYG, V66, P334, DOI 10.4269/ajtmh.2002.66.334
hcfmusp.relation.referenceCrescente JAB, 2009, T ROY SOC TROP MED H, V103, P1250, DOI 10.1016/j.trstmh.2009.06.010
hcfmusp.relation.referenceDas VNR, 2011, T ROY SOC TROP MED H, V105, P661, DOI 10.1016/j.trstmh.2011.08.005
hcfmusp.relation.referenceDavies CR, 1999, PARASITOLOGY, V119, P247, DOI 10.1017/S0031182099004680
hcfmusp.relation.referencede Oliveira ALL, 2008, CAD SAUDE PUBLICA, V24, P2827, DOI 10.1590/S0102-311X2008001200011
hcfmusp.relation.referenceDey A, 2006, Indian J Med Microbiol, V24, P165
hcfmusp.relation.referenceEVANS TG, 1992, J INFECT DIS, V166, P1124, DOI 10.1093/infdis/166.5.1124
hcfmusp.relation.referenceFakhar M, 2008, ANN TROP MED PARASIT, V102, P577, DOI 10.1179/136485908X337526
hcfmusp.relation.referenceFraga TL, 2016, PEDIATR INFECT DIS J, V35, P805, DOI 10.1097/INF.0000000000001172
hcfmusp.relation.referenceFranca AD, 2013, TRANSFUS APHER SCI, V49, P627, DOI 10.1016/j.transci.2013.07.009
hcfmusp.relation.referenceFukutani KF, 2014, BMC INFECT DIS, V14, DOI 10.1186/1471-2334-14-422
hcfmusp.relation.referenceGreiner M, 2000, PREV VET MED, V45, P23, DOI 10.1016/S0167-5877(00)00115-X
hcfmusp.relation.referenceGROGL M, 1993, AM J TROP MED HYG, V49, P308, DOI 10.4269/ajtmh.1993.49.308
hcfmusp.relation.referenceGUEVARA P, 1993, LANCET, V341, P1341, DOI 10.1016/0140-6736(93)90845-8
hcfmusp.relation.referenceHoughton RL, 1998, J INFECT DIS, V177, P1339, DOI 10.1086/515289
hcfmusp.relation.referenceIbrahim ME, 1999, AM J TROP MED HYG, V61, P941, DOI 10.4269/ajtmh.1999.61.941
hcfmusp.relation.referenceJeronimo SMB, 2007, J INFECT DIS, V196, P1261, DOI 10.1086/521682
hcfmusp.relation.referenceJimenez-Marco T, 2012, VOX SANG, V103, P356, DOI 10.1111/j.1423-0410.2012.01622.x
hcfmusp.relation.referenceKubar J, 1997, NAT MED, V3, P368, DOI 10.1038/nm0497-368
hcfmusp.relation.referenceKyriakou DS, 2003, TRANSFUSION MED, V13, P59, DOI 10.1046/j.1365-3148.2003.00420.x
hcfmusp.relation.referenceLANDIS JR, 1977, BIOMETRICS, V33, P159, DOI 10.2307/2529310
hcfmusp.relation.referencele Fichoux Y, 1999, J CLIN MICROBIOL, V37, P1953
hcfmusp.relation.referenceLima ID, 2012, AM J TROP MED HYG, V86, P99, DOI 10.4269/ajtmh.2012.10-0492
hcfmusp.relation.referenceMaia Z, 2012, PLOS NEGLECT TROP D, V6, DOI 10.1371/journal.pntd.0001484
hcfmusp.relation.referenceMansueto P, 2014, TRAVEL MED INFECT DI, V12, P617, DOI 10.1016/j.tmaid.2014.10.011
hcfmusp.relation.referenceMartin-Sanchez J, 2004, AM J TROP MED HYG, V70, P545
hcfmusp.relation.referenceMartinez EZ, 2003, CADERNOS SAUDE COLET, V11, P7
hcfmusp.relation.referenceMestra L, 2011, TRANSFUSION, V51, P1919, DOI 10.1111/j.1537-2995.2011.03092.x
hcfmusp.relation.referenceMichel G, 2011, ACTA TROP, V119, P69, DOI 10.1016/j.actatropica.2011.05.012
hcfmusp.relation.referenceMinisterio da Saude. Secretaria de Vigilancia em Saude. Departamento de Vigilancia Epidemiologica, 2014, MAN VIG CONTR LEISHM
hcfmusp.relation.referenceMonteiro DCS, 2016, EMERG INFECT DIS, V22, P739, DOI 10.3201/eid2204.150065
hcfmusp.relation.referenceMoral L, 2002, T ROY SOC TROP MED H, V96, P129, DOI 10.1016/S0035-9203(02)90278-6
hcfmusp.relation.referenceMoreno EC, 2006, REV SOC BRAS MED TRO, V39, P421, DOI 10.1590/S0037-86822006000500001
hcfmusp.relation.referenceMorillas-Marquez F, 2002, EXP PARASITOL, V100, P71, DOI 10.1006/expr.2001.4678
hcfmusp.relation.referencePeruhype-Magalhaes V, 2012, MEM I OSWALDO CRUZ, V107, P951, DOI 10.1590/S0074-02762012000700019
hcfmusp.relation.referencePirmez C, 1999, J CLIN MICROBIOL, V37, P1819
hcfmusp.relation.referenceRiera C, 2004, T ROY SOC TROP MED H, V98, P102, DOI 10.1016/S0035-9203(03)00015-4
hcfmusp.relation.referenceRiera C, 2008, TRANSFUSION, V48, P1383, DOI 10.1111/j.1537-2995.2008.01708.x
hcfmusp.relation.referenceRodrigues KMP, 2011, BRIT J DERMATOL, V164, P1228, DOI 10.1111/j.1365-2133.2011.10240.x
hcfmusp.relation.referenceRomero HD, 2009, AM J TROP MED HYG, V81, P27
hcfmusp.relation.referenceScarlata F, 2008, T ROY SOC TROP MED H, V102, P394, DOI 10.1016/j.trstmh.2008.01.011
hcfmusp.relation.referenceSchenkel K, 2006, TROP MED INT HEALTH, V11, P1792, DOI 10.1111/j.1365-3156.2006.01735.x
hcfmusp.relation.referenceSilva LA, 2011, AM J TROP MED HYG, V84, P261, DOI 10.4269/ajtmh.2011.10-0092
hcfmusp.relation.referenceSingh S, 2003, J Postgrad Med, V49, P55
hcfmusp.relation.referenceSingh S, 2002, CLIN DIAGN LAB IMMUN, V9, P568, DOI 10.1128/CDLI.9.3.568-572.2002
hcfmusp.relation.referenceTimilsina S, 2016, INDIAN J HEMATOL BLO, V32, P95, DOI 10.1007/s12288-015-0505-6
hcfmusp.relation.referenceUrias Elaine V. R., 2009, Rev. Bras. Hematol. Hemoter., V31, P348
hcfmusp.relation.referenceViana LD, 2008, T ROY SOC TROP MED H, V102, P548, DOI 10.1016/j.trstmh.2008.02.007
hcfmusp.relation.referenceWerneck GL, 2008, CAD SAUDE PUBLICA, V24, P2937, DOI 10.1590/S0102-311X2008001200023
hcfmusp.scopus.lastupdate2024-05-10
relation.isAuthorOfPublication828c0e9b-0b30-4878-9b33-414bd0103241
relation.isAuthorOfPublicationd13852d6-69c6-472f-a761-a06c4204e701
relation.isAuthorOfPublication37cc3ab3-dae7-4f5d-baf5-0e1f169508ce
relation.isAuthorOfPublication.latestForDiscovery828c0e9b-0b30-4878-9b33-414bd0103241
Arquivos
Pacote Original
Agora exibindo 1 - 1 de 1
Imagem de Miniatura
Nome:
art_FRANCA_Leishmania_infection_in_blood_donors_A_new_challenge_2018.PDF
Tamanho:
1.53 MB
Formato:
Adobe Portable Document Format
Descrição:
publishedVersion (English)
Baixar
Coleções
Artigos e Materiais de Revistas Científicas - FM/MPR
Artigos e Materiais de Revistas Científicas - IMT
Artigos e Materiais de Revistas Científicas - LIM/38