OSA and Depression Are Common and Independently Associated With Refractory Angina in Patients With Coronary Artery Disease

Página do item simplificado
dc.contributorSistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP
dc.contributor.authorGEOVANINI, Glaucylara R.
dc.contributor.authorGOWDAK, Luis H. W.
dc.contributor.authorPEREIRA, Alexandre C.
dc.contributor.authorDANZI-SOARES, Naury de Jesus
dc.contributor.authorDOURADO, Luciana O. C.
dc.contributor.authorPOPPI, Nilson T.
dc.contributor.authorCESAR, Luiz Antonio Machado
dc.contributor.authorDRAGER, Luciano F.
dc.contributor.authorLORENZI-FILHO, Geraldo
dc.date.accessioned2015-02-06T19:10:53Z
dc.date.available2015-02-06T19:10:53Z
dc.date.issued2014
dc.description.abstractOBJECTIVE: Refractory angina is a severe form of coronary artery disease (CAD) characterized by persistent angina despite optimal medical therapy. OSA and depression are common in patients with stable CAD and may contribute to a poor prognosis. We hypothesized that OSA and depression are more common and more severe in patients with refractory angina than in patients with stable CAD. METHODS: We used standardized questionnaires and full polysomnography to compare consecutive patients with well-established refractory angina vs consecutive patients with stable CAD evaluated for coronary artery bypass graft surgery. RESULTS: Patients with refractory angina (n = 70) compared with patients with stable CAD (n = 70) were similar in sex distribution (male, 61.5% vs 75.5%; P = .07) and BMI (29.5 +/- 4 kg/m(2) vs 28.5 +/- 4 kg/ m(2), P = .06), and were older (61 +/- 10 y vs 57 +/- 7 y, P = .013), respectively. Patients with refractory angina had significantly more symptoms of daytime sleepiness (Epworth Sleepiness Scale score, 12 +/- 6 vs 8 +/- 5; P < .001), had higher depression symptom scores (Beck Depression Inventory score, 19 +/- 8 vs 10 +/- 8; P < .001) despite greater use of antidepressants, had a higher apnea-hypopnea index (AHI) (AHI, 37 +/- 30 events/h vs 23 +/- 20 events/h; P = .001), higher proportion of oxygen saturation < 90% during sleep (8% + 13 vs 4% + 9, P = .04), and a higher proportion of severe OSA (AHI >= 30 events/h, 48% vs 27%; P = .009) than patients with stable CAD. OSA (P = .017), depression (P < .001), higher Epworth Sleepiness Scale score (P = .007), and lower sleep efficiency (P = .016) were independently associated with refractory angina in multivariate analysis. CONCLUSIONS: OSA and depression are independently associated with refractory angina and may contribute to poor cardiovascular outcome.
dc.description.indexMEDLINE
dc.description.sponsorshipFundacao de Amparo a Pesquisa do Estado de Sao Paulo (FAPESP)
dc.description.sponsorshipFundacao Zerbini, Sao Paulo, Brazil
dc.identifier.citationCHEST, v.146, n.1, p.73-80, 2014
dc.identifier.doi10.1378/chest.13-2885
dc.identifier.issn0012-3692
dc.identifier.urihttps://observatorio.fm.usp.br/handle/OPI/8370
dc.language.isoeng
dc.publisherAMER COLL CHEST PHYSICIANS
dc.relation.ispartofChest
dc.rightsrestrictedAccess
dc.rights.holderCopyright AMER COLL CHEST PHYSICIANS
dc.subject.otherobstructive sleep-apnea
dc.subject.otherbrazilian portuguese version
dc.subject.otherpositive airway pressure
dc.subject.othercardiovascular outcomes
dc.subject.otherquality index
dc.subject.othermanagement
dc.subject.otherrisk
dc.subject.otherrevascularization
dc.subject.otheratherosclerosis
dc.subject.otherhypertension
dc.subject.wosCritical Care Medicine
dc.subject.wosRespiratory System
dc.titleOSA and Depression Are Common and Independently Associated With Refractory Angina in Patients With Coronary Artery Disease
dc.typearticle
dc.type.categoryoriginal article
dc.type.versionpublishedVersion
dspace.entity.typePublication
hcfmusp.citation.scopus25
hcfmusp.contributor.author-fmusphcGLAUCYLARA REIS GEOVANINI
hcfmusp.contributor.author-fmusphcLUIS HENRIQUE WOLFF GOWDAK
hcfmusp.contributor.author-fmusphcALEXANDRE DA COSTA PEREIRA
hcfmusp.contributor.author-fmusphcNAURY DE JESUS DANZI SOARES
hcfmusp.contributor.author-fmusphcLUCIANA OLIVEIRA CASCAES DOURADO
hcfmusp.contributor.author-fmusphcNILSON TAVARES POPPI
hcfmusp.contributor.author-fmusphcLUIZ ANTONIO MACHADO CESAR
hcfmusp.contributor.author-fmusphcLUCIANO FERREIRA DRAGER
hcfmusp.contributor.author-fmusphcGERALDO LORENZI FILHO
hcfmusp.description.beginpage73
hcfmusp.description.endpage80
hcfmusp.description.issue1
hcfmusp.description.volume146
hcfmusp.origemWOS
hcfmusp.origem.scopus2-s2.0-84903836175
hcfmusp.origem.wosWOS:000339729800024
hcfmusp.publisher.cityGLENVIEW
hcfmusp.publisher.countryUSA
hcfmusp.relation.referenceAmerican Academy of Sleep Medicine, 2007, AASM MAN SCOR SLEEP
hcfmusp.relation.referenceBarefoot JC, 1996, AM J CARDIOL, V78, P613, DOI 10.1016/S0002-9149(96)00380-3
hcfmusp.relation.referenceBertolazi AN, 2011, SLEEP MED, V12, P70, DOI 10.1016/j.sleep.2010.04.020
hcfmusp.relation.referenceBrorsson B, 2002, HEART, V87, P140, DOI 10.1136/heart.87.2.140
hcfmusp.relation.referenceBUYSSE DJ, 1989, PSYCHIAT RES, V28, P193, DOI 10.1016/0165-1781(89)90047-4
hcfmusp.relation.referenceCappuccio FP, 2011, EUR HEART J, V32, P1484, DOI 10.1093/eurheartj/ehr007
hcfmusp.relation.referenceCARNEY RM, 1988, PSYCHOSOM MED, V50, P627
hcfmusp.relation.referenceCelano CM, 2011, CARDIOL REV, V19, P130, DOI 10.1097/CRD.0b013e31820e8106
hcfmusp.relation.referenceDanzi-Soares ND, 2012, CORONARY ARTERY DIS, V23, P31, DOI 10.1097/MCA.0b013e32834df5d0
hcfmusp.relation.referenceDrager LF, 2010, AM J CARDIOL, V105, P1135, DOI 10.1016/j.amjcard.2009.12.017
hcfmusp.relation.referenceDrager Luciano F, 2009, J Cardiometab Syndr, V4, P89, DOI 10.1111/j.1559-4572.2008.00046.x
hcfmusp.relation.referenceDrager LF, 2010, PLOS ONE, V5, DOI 10.1371/journal.pone.0012065
hcfmusp.relation.referenceDrager LF, 2011, CHEST, V140, P534, DOI 10.1378/chest.10-2223
hcfmusp.relation.referenceDrager LF, 2013, J AM COLL CARDIOL, V62, P569, DOI 10.1016/j.jacc.2013.05.045
hcfmusp.relation.referenceDrager LF, 2007, AM J RESP CRIT CARE, V176, P706, DOI 10.1164/rccm.200703-500OC
hcfmusp.relation.referenceDrager LF, 2010, ATHEROSCLEROSIS, V208, P490, DOI 10.1016/j.atherosclerosis.2009.08.016
hcfmusp.relation.referenceGibbons RJ, ACC AHA 2022 GUID UP
hcfmusp.relation.referenceGomes-Oliveira MH, 2012, REV BRAS PSIQUIATR, V34, P389, DOI 10.1016/j.rbp.2012.03.005
hcfmusp.relation.referenceHenry TD, 2013, EUR HEART J, V34, P2683, DOI 10.1093/eurheartj/eht165
hcfmusp.relation.referenceHerrmann C, 2000, J PSYCHOSOM RES, V48, P455, DOI 10.1016/S0022-3999(99)00086-0
hcfmusp.relation.referenceJOHNS MW, 1991, SLEEP, V14, P540
hcfmusp.relation.referenceLenzen Mattie, 2006, Eur J Cardiovasc Nurs, V5, P115, DOI 10.1016/j.ejcnurse.2006.01.003
hcfmusp.relation.referenceLenzen MJ, 2005, EUR HEART J, V26, P1169, DOI 10.1093/eurheartj/ehi238
hcfmusp.relation.referenceLesperance F, 2000, ARCH INTERN MED, V160, P1354, DOI 10.1001/archinte.160.9.1354
hcfmusp.relation.referenceManchanda A, 2011, CARDIOL J, V18, P343
hcfmusp.relation.referenceMannheimer C, 2002, EUR HEART J, V23, P355, DOI 10.1053/euhj.2001.2706
hcfmusp.relation.referenceMarin JM, 2005, LANCET, V365, P1046, DOI 10.1016/S0140-6736(05)71141-7
hcfmusp.relation.referenceMcGillion M, 2012, CAN J CARDIOL, V28, pS20, DOI 10.1016/j.cjca.2011.07.007
hcfmusp.relation.referencePedrosa RP, 2010, CHEST, V137, P1078, DOI 10.1378/chest.09-2335
hcfmusp.relation.referencePedrosa RP, 2011, HYPERTENSION, V58, P811, DOI 10.1161/HYPERTENSIONAHA.111.179788
hcfmusp.relation.referencePunjabi Naresh M, 2008, Proc Am Thorac Soc, V5, P136, DOI 10.1513/pats.200709-155MG
hcfmusp.relation.referenceShahar E, 2001, AM J RESP CRIT CARE, V163, P19
hcfmusp.relation.referenceSorajja D, 2008, CHEST, V133, P927, DOI 10.1378/chest.07-2544
hcfmusp.relation.referenceSteiner S, 2010, CHEST, V137, P516, DOI 10.1378/chest.09-1136
hcfmusp.scopus.lastupdate2024-05-10
relation.isAuthorOfPublicatione6ac43e5-ef26-45c1-ac7b-c9660dfd16dc
relation.isAuthorOfPublicatione0ab09b6-a894-4b61-b5ce-0fde4671de72
relation.isAuthorOfPublication415ce7ca-65c1-4699-b6f4-19dae8b03849
relation.isAuthorOfPublicationcd206949-56f2-47ba-9a73-9f1f7f25b568
relation.isAuthorOfPublication749b902d-9bcb-4c75-848b-f893102cff32
relation.isAuthorOfPublication292fecac-5919-4710-8ceb-5670f4274760
relation.isAuthorOfPublicationdf34619b-e66d-4b7a-96fa-b3039f66f567
relation.isAuthorOfPublication45056c2e-919d-4fc1-97d3-356e54fe3385
relation.isAuthorOfPublication50462524-ec24-4cf2-9c62-67193479cd0c
relation.isAuthorOfPublication.latestForDiscoverye6ac43e5-ef26-45c1-ac7b-c9660dfd16dc
Arquivos
Pacote Original
Agora exibindo 1 - 1 de 1
Nenhuma Miniatura disponível
Nome:
art_GEOVANINI_OSA_and_Depression_Are_Common_and_Independently_Associated_2014.PDF
Tamanho:
275.81 KB
Formato:
Adobe Portable Document Format
Descrição:
publishedVersion (English)
Baixar
Coleções
Artigos e Materiais de Revistas Científicas - FM/MCP
Artigos e Materiais de Revistas Científicas - FM/MCM
Artigos e Materiais de Revistas Científicas - HC/InCor
Artigos e Materiais de Revistas Científicas - LIM/09
Artigos e Materiais de Revistas Científicas - LIM/13
Artigos e Materiais de Revistas Científicas - ODS/03