COVID-19: detection methods in post-mortem samples

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dc.contributorSistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP
dc.contributor.authorTEDESCO, Ilaria
dc.contributor.authorMARINO, Federica Zito
dc.contributor.authorRONCHI, Andrea
dc.contributor.authorNETO, Amaro Nunes Duarte
dc.contributor.authorDOLHNIKOFF, Marisa
dc.contributor.authorMUNICINO, Maurizio
dc.contributor.authorCAMPOBASSO, Carlo Pietro
dc.contributor.authorPANNONE, Giuseppe
dc.contributor.authorFRANCO, Renato
dc.date.accessioned2024-02-15T14:53:17Z
dc.date.available2024-02-15T14:53:17Z
dc.date.issued2023
dc.description.abstractCOVID-19 identification is routinely performed on fresh samples, such as nasopharyngeal and oropharyngeal swabs, even if, the detection of the virus in formalin-fixed paraffinembedded (FFPE) autopsy tissues could help to underlie mechanisms of the pathogenesis that are not well understood. The gold standard for COVID-19 detection in FFPE samples remains the qRT-PCR as in swab samples, contextually other methods have been developed, including immunohistochemistry (IHC), and in situ hybridization (ISH). In this manuscript, we summarize the main data regarding the methods of COVID-19 detection in pulmonary and extra-pulmonary post-mortem samples, and especially the sensitivity and specificity of these assays will be discussed.eng
dc.description.indexMEDLINE
dc.description.indexPubMed
dc.description.indexWoS
dc.description.indexScopus
dc.identifier.citationPATHOLOGICA, v.115, n.5, p.263-274, 2023
dc.identifier.doi10.32074/1591-951X-933
dc.identifier.eissn1591-951X
dc.identifier.issn0031-2983
dc.identifier.urihttps://observatorio.fm.usp.br/handle/OPI/58040
dc.language.isoeng
dc.publisherPACINI EDITOREeng
dc.relation.ispartofPathologica
dc.rightsopenAccesseng
dc.rights.holderCopyright PACINI EDITOREeng
dc.subjectCOVID-19eng
dc.subjectimmunohistochemistryeng
dc.subjectin situ hybridizationeng
dc.subjectautopsy sampleseng
dc.subject.othersars-cov-2eng
dc.subject.otherautopsyeng
dc.subject.otherpcreng
dc.subject.wosPathologyeng
dc.titleCOVID-19: detection methods in post-mortem sampleseng
dc.typearticleeng
dc.type.categoryrevieweng
dc.type.versionpublishedVersioneng
dspace.entity.typePublication
hcfmusp.affiliation.countryItália
hcfmusp.affiliation.countryisoit
hcfmusp.author.externalTEDESCO, Ilaria:Univ Campania L Vanvitelli, Dept Mental & Phys Hlth & Prevent Med, Pathol Unit, Naples, Italy
hcfmusp.author.externalMARINO, Federica Zito:Univ Campania L Vanvitelli, Dept Mental & Phys Hlth & Prevent Med, Pathol Unit, Naples, Italy
hcfmusp.author.externalRONCHI, Andrea:Univ Campania L Vanvitelli, Dept Mental & Phys Hlth & Prevent Med, Pathol Unit, Naples, Italy
hcfmusp.author.externalMUNICINO, Maurizio:S Giuliano Hosp, Forens Med Unit, Giugliano In Campania, Italy
hcfmusp.author.externalCAMPOBASSO, Carlo Pietro:Univ Campania Luigi Vanvitelli, Dept Expt Med, Naples, Italy
hcfmusp.author.externalPANNONE, Giuseppe:Univ Foggia, Dept Clin & Expt Med, Anat Pathol Unit, Foggia, Italy
hcfmusp.author.externalFRANCO, Renato:Univ Campania L Vanvitelli, Dept Mental & Phys Hlth & Prevent Med, Pathol Unit, Naples, Italy
hcfmusp.citation.scopus0
hcfmusp.contributor.author-fmusphcAMARO NUNES DUARTE NETO
hcfmusp.contributor.author-fmusphcMARISA DOLHNIKOFF
hcfmusp.description.beginpage263
hcfmusp.description.endpage274
hcfmusp.description.issue5
hcfmusp.description.volume115
hcfmusp.origemWOS
hcfmusp.origem.pubmed38054901
hcfmusp.origem.scopus2-s2.0-85178850571
hcfmusp.origem.wosWOS:001111170500003
hcfmusp.publisher.cityPISAeng
hcfmusp.publisher.countryITALYeng
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Artigos e Materiais de Revistas Científicas - FM/MPT
Artigos e Materiais de Revistas Científicas - COVID-19
Artigos e Materiais de Revistas Científicas - HC/ICHC
Artigos e Materiais de Revistas Científicas - LIM/05
Artigos e Materiais de Revistas Científicas - LIM/06