Cardiovascular risk factors in patients with first-episode psychosis in Sao Paulo, Brazil

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dc.contributorSistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP
dc.contributor.authorBENSENOR, Isabela M.
dc.contributor.authorBRUNONI, Andre R.
dc.contributor.authorPILAN, Luis Augusto
dc.contributor.authorGOULART, Alessandra C.
dc.contributor.authorBUSATTO, Geraldo F.
dc.contributor.authorLOTUFO, Paulo A.
dc.contributor.authorSCAZUFCA, Marcia
dc.contributor.authorMENEZES, Paulo R.
dc.date.accessioned2013-07-30T14:41:37Z
dc.date.available2013-07-30T14:41:37Z
dc.date.issued2012
dc.description.abstractObjective: The objective was to evaluate the cardiovascular profile of first-episode psychosis patients in Sao Paulo, Brazil, an issue that has not been sufficiently explored in low-/middle-income countries. Method: A cross-sectional study was performed 1 to 3 years after an initial, larger survey that assessed first-episode psychosis in sao Paulo. We evaluated cardiovascular risk factors and lifestyle habits using standard clinical examination and laboratory evaluation. Results: Of 151 contacted patients, 82 agreed to participate (mean age=35 years; 54% female). The following diagnoses were found: 20.7% were obese, 29.3% had hypertension, 39.0% had dyslipidemia, 19.5% had metabolic syndrome, and 1.2% had a >20% 10-year risk of coronary heart disease based on Framingham score. Also, 72% were sedentary, 25.6% were current smokers, and 7.3% reported a heavy alcohol intake. Conclusion: Compared to other samples, ours presented a distinct profile of higher rates of hypertension and diabetes (possibly due to dietary habits) and lower rates of smoking and alcohol intake (possibly due to higher dependence on social support). Indirect comparison vs. healthy, age-matched Brazilians revealed that our sample had higher frequencies of hypertension, diabetes and metabolic syndrome. Therefore, we confirmed a high cardiovascular risk in first-episode psychosis in Brazil. Transcultural studies are needed to investigate to which extent lifestyle contributes to such increased risk.
dc.description.indexMEDLINE
dc.description.sponsorshipFAPESP, Fundacao de Amparo a Pesquisa do Estado de Sao Paulo, Sao Paulo, Brazil
dc.description.sponsorshipCNPq (Conselho Nacional de Pesquisa), Brazil
dc.identifier.citationGENERAL HOSPITAL PSYCHIATRY, v.34, n.3, p.268-275, 2012
dc.identifier.doi10.1016/j.genhosppsych.2011.12.010
dc.identifier.issn0163-8343
dc.identifier.urihttps://observatorio.fm.usp.br/handle/OPI/391
dc.language.isoeng
dc.publisherELSEVIER SCIENCE INC
dc.relation.ispartofGeneral Hospital Psychiatry
dc.rightsrestrictedAccess
dc.rights.holderCopyright ELSEVIER SCIENCE INC
dc.subjectPsychosis
dc.subjectSchizophrenia
dc.subjectCardiovascular disease
dc.subjectLifestyle habits
dc.subjectHypertension
dc.subjectDiabetes
dc.subject.othermetabolic syndrome
dc.subject.otherbipolar disorder
dc.subject.otheratypical antipsychotics
dc.subject.otherschizophrenic-patients
dc.subject.otherexcess mortality
dc.subject.otherweight-gain
dc.subject.otherprevalence
dc.subject.otherdisease
dc.subject.otherindividuals
dc.subject.othersmoking
dc.subject.wosPsychiatry
dc.titleCardiovascular risk factors in patients with first-episode psychosis in Sao Paulo, Brazil
dc.typearticle
dc.type.categoryoriginal article
dc.type.versionpublishedVersion
dspace.entity.typePublication
hcfmusp.citation.scopus14
hcfmusp.contributor.author-fmusphcISABELA JUDITH MARTINS BENSEñOR
hcfmusp.contributor.author-fmusphcANDRE RUSSOWSKY BRUNONI
hcfmusp.contributor.author-fmusphcLUIS AUGUSTO SALES LIMA PILAN
hcfmusp.contributor.author-fmusphcALESSANDRA CARVALHO GOULART
hcfmusp.contributor.author-fmusphcGERALDO BUSATTO FILHO
hcfmusp.contributor.author-fmusphcPAULO ANDRADE LOTUFO
hcfmusp.contributor.author-fmusphcMARCIA SCAZUFCA
hcfmusp.contributor.author-fmusphcPAULO ROSSI MENEZES
hcfmusp.description.beginpage268
hcfmusp.description.endpage275
hcfmusp.description.issue3
hcfmusp.description.volume34
hcfmusp.lim.ref2012
hcfmusp.origemWOS
hcfmusp.origem.pubmed22305369
hcfmusp.origem.scopus2-s2.0-84860384275
hcfmusp.origem.wosWOS:000304237600009
hcfmusp.publisher.cityNEW YORK
hcfmusp.publisher.countryUSA
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hcfmusp.remissive.sponsorshipCNPq
hcfmusp.remissive.sponsorshipFAPESP
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