Chronic Obstructive Pulmonary Disease-Related Mortality in Brazil, 2000-2019: A Multiple-Cause-of-Death Study

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dc.contributorSistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP
dc.contributor.authorSANTO, Augusto Hasiak
dc.contributor.authorFERNANDES, Frederico Leon Arrabal
dc.date.accessioned2022-06-20T15:41:21Z
dc.date.available2022-06-20T15:41:21Z
dc.date.issued2022
dc.description.abstractChronic obstructive pulmonary disease (COPD) remains a compelling cause of morbidity and mortality; however, it is underestimated and undertreated in Brazil. Using multiple causes of death data from the Information System on Mortality, we evaluated, from 2000 to 2019, national proportional mortality; trends in mortality rates stratified by age, sex, and macro-region; and causes of death and seasonal variation, considering COPD as an underlying and associated cause of death. COPD occurred in 1,132,968 deaths, corresponding to a proportional mortality of 5.0% (5.2% and 4.7% among men and women), 67.6% as the underlying, and 32.4% as an associated cause of death. The standardized mortality rate decreased by 25.8% from 2000 to 2019, and the underlying, associated, male and female, Southeast, South, and Center-West region deaths revealed decreasing standardized mortality trends. The mean age at death increased from 73.2 (+/- 12.5) to 76.0 (+/- 12.0) years of age. Respiratory diseases were the leading underlying causes, totaling 69.8%, with COPD itself reported for 67.6% of deaths, followed by circulatory diseases (15.8%) and neoplasms (6.24%). Respiratory failure, pneumonia, septicemia, and hypertensive diseases were the major associated causes of death. Significant seasonal variations, with the highest proportional COPD mortality during winter, occurred in the southeast, south, and center-west regions. This study discloses the need and value to accurately document epidemiologic trends related to COPD in Brazil, provided its burden on mortality in older age as a significant cause of death, aiming at effective planning of mortality prevention and control.eng
dc.description.indexMEDLINEeng
dc.identifier.citationCOPD-JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE, v.19, n.1, p.216-225, 2022
dc.identifier.doi10.1080/15412555.2022.2061934
dc.identifier.eissn1541-2563
dc.identifier.issn1541-2555
dc.identifier.urihttps://observatorio.fm.usp.br/handle/OPI/47425
dc.language.isoeng
dc.publisherTAYLOR & FRANCIS INCeng
dc.relation.ispartofCopd-Journal of Chronic Obstructive Pulmonary Disease
dc.rightsrestrictedAccesseng
dc.rights.holderCopyright TAYLOR & FRANCIS INCeng
dc.subjectChronic obstructive pulmonary diseaseeng
dc.subjectcause of deatheng
dc.subjectdeath certificateeng
dc.subjectmortalityeng
dc.subject.othercopd mortalityeng
dc.subject.otherunited-stateseng
dc.subject.otherlung-diseaseeng
dc.subject.othertrendseng
dc.subject.othermorbiditieseng
dc.subject.wosMedicine, General & Internaleng
dc.titleChronic Obstructive Pulmonary Disease-Related Mortality in Brazil, 2000-2019: A Multiple-Cause-of-Death Studyeng
dc.typearticleeng
dc.type.categoryoriginal articleeng
dc.type.versionpublishedVersioneng
dspace.entity.typePublication
hcfmusp.author.externalSANTO, Augusto Hasiak:Univ Sao Paulo, Dept Epidemiol, Fac Saude Publ, Rua Para,21 Apt 62, BR-01243020 Sao Paulo, Brazil
hcfmusp.citation.scopus4
hcfmusp.contributor.author-fmusphcFREDERICO LEON ARRABAL FERNANDES
hcfmusp.description.beginpage216
hcfmusp.description.endpage225
hcfmusp.description.issue1
hcfmusp.description.volume19
hcfmusp.origemWOS
hcfmusp.origem.pubmed35416733
hcfmusp.origem.scopus2-s2.0-85128135037
hcfmusp.origem.wosWOS:000783504500001
hcfmusp.publisher.cityPHILADELPHIAeng
hcfmusp.publisher.countryUSAeng
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