Varicocele-Associated Infertility and the Role of Oxidative Stress on Sperm DNA Fragmentation
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Citações na Scopus
8
Tipo de produção
article
Data de publicação
2021
Título da Revista
ISSN da Revista
Título do Volume
Editora
FRONTIERS MEDIA SA
Autores
NUNES, Thiago Fagundes
Citação
FRONTIERS IN REPRODUCTIVE HEALTH, v.3, article ID 695992, 4p, 2021
Resumo
Varicocele has been extensively described and studied as the most important reversible cause of male infertility. Its impact on semen parameters, pregnancy rates, and assisted reproductive outcomes have been associated with multifactorial aspects, most of them converging to increase of reactive oxygen species (ROS). More recently, sperm DNA fragmentation has gained significant attention and potential clinical use, although the body of evidence still needs further evolution. The associations between sperm DNA damage and a variety of disorders, including varicocele itself, share common pathways to ROS increase. This mini-review discusses different aspects related to the etiology of ROS and its relation to varicocele and potential mechanisms of DNA damage.
Palavras-chave
sperm DNA fragmentation (SDF), varicocele, male infertility, reactive oxygen species, oxidative stress
Referências
- Agarwal A, 2006, REPROD BIOMED ONLINE, V12, P630, DOI 10.1016/S1472-6483(10)61190-X
- Agarwal A, 2007, UROLOGY, V70, P532, DOI 10.1016/j.urology.2007.04.011
- Agarwal A, 2019, EXPERT REV MOL DIAGN, V19, P443, DOI 10.1080/14737159.2019.1614916
- Agarwal A, 2012, NAT REV UROL, V9, P678, DOI 10.1038/nrurol.2012.197
- Altintas R, 2016, ANDROLOGY-US, V4, P442, DOI 10.1111/andr.12172
- Champroux A, 2016, BASIC CLIN ANDROL, V26, DOI 10.1186/s12610-016-0044-5
- Cho CL, 2016, ASIAN J ANDROL, V18, P186, DOI 10.4103/1008-682X.170441
- Dada R, 2017, TRANSL ANDROL UROL, V6, pS691, DOI 10.21037/tau.2017.05.26
- Dave P, 2021, ANDROLOGIA, V53, DOI 10.1111/and.13629
- de Catalfo GEH, 2007, INT J ANDROL, V30, P519, DOI 10.1111/j.1365-2605.2007.00753.x
- Esteves SC, 2020, ANDROLOGY-US, V8, P53, DOI 10.1111/andr.12724
- Fretz PC, 2002, UROL CLIN N AM, V29, P921, DOI 10.1016/S0094-0143(02)00075-7
- Gonzalez-Marin C, 2012, INT J MOL SCI, V13, P14026, DOI 10.3390/ijms131114026
- GORELICK JI, 1993, FERTIL STERIL, V59, P613
- Hamada A, 2013, NAT REV UROL, V10, P26, DOI 10.1038/nrurol.2012.198
- Jarow JP, 1996, UROLOGY, V47, P73, DOI 10.1016/S0090-4295(99)80385-9
- Jensen CFS, 2017, NAT REV UROL, V14, P523, DOI 10.1038/nrurol.2017.98
- Jeremias JT, 2021, INT BRAZ J UROL, V47, P275, DOI [10.1590/s1677-5538.ibju.2019.0827, 10.1590/S1677-5538.IBJU.2019.0827]
- Masson P, 2014, UROL CLIN N AM, V41, P129, DOI 10.1016/j.ucl.2013.08.001
- Mostafa T, 2009, ANDROLOGIA, V41, P125, DOI 10.1111/j.1439-0272.2008.00900.x
- Muratori M, 2015, MOL MED, V21, DOI 10.2119/molmed.2014.00158
- Neto FTL, 2021, FERTIL STERIL, V116, P696, DOI 10.1016/j.fertnstert.2021.04.003
- Selvam MKP, 2021, ANDROLOGIA, V53, DOI 10.1111/and.13706
- Pastuszak AW, 2015, ASIAN J ANDROL, V17, P659, DOI 10.4103/1008-682X.153539
- Peter N., 2020, DIAGNOSIS TREATMENT
- Qiu DX, 2021, ANDROLOGIA, V53, DOI 10.1111/and.13885
- Ribas-Maynou J, 2019, GENES-BASEL, V10, DOI 10.3390/genes10020105
- Ribas-Maynou J, 2012, PLOS ONE, V7, DOI 10.1371/journal.pone.0044679
- Ritchie C, 2021, ANDROLOGIA, V53, DOI 10.1111/and.13581
- Sakamoto Y, 2008, BJU INT, V101, P1547, DOI 10.1111/j.1464-410X.2008.07517.x
- Saleh RA, 2002, J ANDROL, V23, P737
- Salonia A., 2021, EUR ASS UROL, P282
- Sasson Daniel C, 2020, JAMA, V323, P2210, DOI 10.1001/jama.2020.0397
- Tiseo BC, 2016, ASIAN J ANDROL, V18, P239, DOI 10.4103/1008-682X.172639
- Wang SL, 2021, FERTIL STERIL, V116, P657, DOI 10.1016/j.fertnstert.2021.06.053
- Wang YJ, 2012, REPROD BIOMED ONLINE, V25, P307, DOI 10.1016/j.rbmo.2012.05.002
- World Health Organization, 2021, WHO LAB MAN EX PROC, VSixth, P276
- Zini A, 2011, FERTIL STERIL, V96, P1283, DOI 10.1016/j.fertnstert.2011.10.016