Please use this identifier to cite or link to this item: https://observatorio.fm.usp.br/handle/OPI/1224
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dc.contributorSistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP-
dc.contributor.authorTOPORCOV, Tatiana Natasha-
dc.contributor.authorTAVARES, Giovanna Emann-
dc.contributor.authorROTUNDO, Ligia Drovandi Braga-
dc.contributor.authorVACCAREZZA, Gabriela Fuerst-
dc.contributor.authorBIAZEVIC, Maria Gabriela Haye-
dc.contributor.authorBRASILEIRO, Rosana Sarmento-
dc.contributor.authorCARVALHO, Marcos Brasilino de-
dc.contributor.authorMICHALUART JUNIOR, Pedro-
dc.contributor.authorKOWALSKI, Luiz Paulo-
dc.contributor.authorANTUNES, Jose Leopoldo Ferreira-
dc.date.accessioned2013-07-30T17:17:25Z-
dc.date.available2013-07-30T17:17:25Z-
dc.date.issued2012-
dc.identifier.citationNUTRITION AND CANCER-AN INTERNATIONAL JOURNAL, v.64, n.8, p.1182-1189, 2012-
dc.identifier.issn0163-5581-
dc.identifier.urihttps://observatorio.fm.usp.br/handle/OPI/1224-
dc.description.abstractRecent systematic reviews concluded that the frequent consumption of fruits and vegetables is inversely associated with the risk of oral cancer. We assessed this association, specifically comparing results obtained to nonsmokers and smokers, as well to nondrinkers and drinkers. We conducted a case-control study involving 296 patients with oral squamous cell carcinoma (cases) attended in 3 major hospitals of Sao Paulo, Brazil, paired with 296 controls, recruited from outpatient units of the same hospitals. Multivariate models assessed the effect of fruits and salads according to smoking and drinking. The intake of fruit was associated with the prevention of the disease in the specific assessment among light [odds ratio (OR) = 0.46; 95% confidence interval (CI) = 0.27-0.78) and heavy (OR = 0.30; 95% CI = 0.14-0.65) smokers. The same was observed for vegetables consumption. For nonsmokers, no fruit (OR = 50; 95% CI = 0.22-1.12) or vegetable (for tomato, OR = 0.53; 95% CI = 0.31-0.93) was associated with reduced risk of oral and oropharyngeal cancer. Similar results were found in the stratified analysis according to drinking status with OR = 0.51 (95% CI = 0.30-0.87) and 0.18 for fruits (95% CI = 0.07-0.45), respectively, for light and heavy drinkers. This observation suggests that the protective effect of fruit and salad intake may modulate the deleterious effects from tobacco and alcohol.-
dc.description.sponsorshipFAPESP (Fundacao de Amparo a Pesquisa no Estado de Sao Paulo) [06/58229-0]-
dc.description.sponsorshipCNPq (Conselho Nacional de Desenvolvimento Cientifico e Tecnologico) [301191/2007-7]-
dc.language.isoeng-
dc.publisherROUTLEDGE JOURNALS, TAYLOR & FRANCIS LTD-
dc.relation.ispartofNutrition and Cancer-An International Journal-
dc.rightsrestrictedAccess-
dc.subject.othersquamous-cell carcinoma-
dc.subject.otherpharyngeal cancer-
dc.subject.otheroropharyngeal cancer-
dc.subject.otherrisk-
dc.subject.otherantioxidants-
dc.subject.otherconsumption-
dc.subject.othersmoking-
dc.subject.otherfruit-
dc.subject.otherfat-
dc.titleDo Tobacco and Alcohol Modify Protective Effects of Diet on Oral Carcinogenesis?-
dc.typearticle-
dc.rights.holderCopyright ROUTLEDGE JOURNALS, TAYLOR & FRANCIS LTD-
dc.identifier.doi10.1080/01635581.2012.721155-
dc.identifier.pmid23163847-
dc.subject.wosOncology-
dc.subject.wosNutrition & Dietetics-
dc.type.categoryoriginal article-
dc.type.versionpublishedVersion-
hcfmusp.author.externalTOPORCOV, Tatiana Natasha:Univ Sao Paulo, Sch Publ Hlth, Fac Saude Publ, Sao Paulo, Brazil-
hcfmusp.author.externalTAVARES, Giovanna Emann:Univ Sao Paulo, Fac Odontol, Sao Paulo, Brazil-
hcfmusp.author.externalROTUNDO, Ligia Drovandi Braga:Univ Sao Paulo, Fac Odontol, Sao Paulo, Brazil-
hcfmusp.author.externalVACCAREZZA, Gabriela Fuerst:Univ Sao Paulo, Fac Odontol, Sao Paulo, Brazil-
hcfmusp.author.externalBIAZEVIC, Maria Gabriela Haye:Univ Sao Paulo, Fac Odontol, Sao Paulo, Brazil-
hcfmusp.author.externalKOWALSKI, Luiz Paulo:Hosp Canc AC Camargo, Sao Paulo, Brazil-
hcfmusp.description.beginpage1182-
hcfmusp.description.endpage1189-
hcfmusp.description.issue8-
hcfmusp.description.volume64-
hcfmusp.origemWOS-
hcfmusp.origem.id2-s2.0-84873703580-
hcfmusp.origem.idWOS:000311457700007-
hcfmusp.publisher.cityABINGDON-
hcfmusp.publisher.countryENGLAND-
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dc.description.indexMEDLINE-
dc.identifier.eissn1532-7914-
hcfmusp.remissive.sponsorshipCNPq-
hcfmusp.remissive.sponsorshipFAPESP-
hcfmusp.lim.ref2012-
hcfmusp.citation.scopus12-
hcfmusp.scopus.lastupdate2022-05-06-
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