Instituto de Medicina Tropical - IMT

O Instituto de Medicina Tropical de São Paulo (IMTSP) foi criado em 1959 para desenvolver pesquisas e fornecer subsídio científico e tecnológico para o diagnóstico, tratamento, controle e prevenção das doenças tropicais e grandes endemias do nosso país. Durante 40 anos o IMTSP esteve ligado à Faculdade de Medicina da Universidade de São Paulo, mas, a partir de dezembro de 2000, tornou-se uma unidade autônoma, um Instituto Especializado da USP.

As pesquisas no IMTSP abrangem diversos aspectos da ciência médica nessa área, como o diagnóstico, a patogenia e o tratamento, voltando-se também para as questões epidemiológicas e de prevenção. O IMTSP, além de instituição de pesquisa, também é um centro de formação, de aperfeiçoamento e de prestação de serviços especializados na área: possui um curso regular de extensão sobre saúde dos viajantes, para a comunidade externa e no 2º semestre de 2007 teve o curso de Pós-Graduação em Medicina Tropical e Saúde Internacional aprovado pela Capes.

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Recent Submissions

  1. NS1-based ELISA test efficiently detects dengue infections without cross-reactivity with Zika virus


    Objectives: The aim of this study was to achieve greater specificity of dengue virus (DENV) serological tests based on a recombinant antigen derived from non-structural protein 1 (Delta NS1) with regard to cross-reactive Zika virus (ZIKV) anti-NS1 antibody responses. This is of relevance in endem...

  2. One Health approach on human seroprevalence of anti-Toxocara antibodies, Toxocara spp. eggs in dogs and sand samples between seashore mainland and island areas of southern Brazil

    ONE HEALTH, v.13, article ID 100353, 7p, 2021

    Toxocariasis, caused by Toxocara spp. nematodes, is among the top 5 neglected parasitic diseases worldwide; however, no comprehensive study to date has serologically compared infections in people and their dogs and environmentally contaminated soil or sand of mainland and island locations. Accord...

  3. Detection of SARS-CoV-2 on conjunctiva by rRT-PCR in patients with severe form of COVID-19



    ATHEROSCLEROSIS, v.331, p.E139-E140, 2021

  5. Disparity between scientific accomplishment and biotechnology availability in Brazil

    SCIENCE PROGRESS, v.104, n.2, article ID 368504211028373, 3p, 2021

    Despite being among the world's leaders in scientific output, Brazil ranks 66th among countries in the production of reagents and supplies needed for state-of-the-art scientific analyses. The production of needed reagents and equipment for experimental analyses and patient diagnostics is sorely l...

  6. Low prevalence of human gammaherpesvirus 8 (HHV-8) infection among HIV-infected pregnant women in Rio De Janeiro, Brazil

    JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE, v.34, n.20, p.3458-3461, 2021

    Pregnant women coinfected with the human immunodeficiency virus (HIV) and human gammaherpesvirus 8 (HHV-8) are at higher risk of Kaposi's sarcoma development, increased viral load, and vertical transmission of these viruses. A total of 131 pregnant women infected with HIV were examined for antibo...

  7. Latent and active tuberculosis infection in allogeneic hematopoietic stem cell transplant recipients: a prospective cohort study

    BONE MARROW TRANSPLANTATION, v.56, n.9, p.2241-2247, 2021

    Tuberculosis (TB) is a major infectious complication in hematopoietic stem cell transplant (HSCT) recipients in countries with high TB prevalence. Identifying and treating latent tuberculosis infection (LTBI) helps to prevent TB reactivation after transplantation. Few studies have compared the tu...

  8. Serosurvey of anti-Toxocara antibodies and risk factors in adolescent and adult pregnant women of southeastern Brazil

    PLOS NEGLECTED TROPICAL DISEASES, v.15, n.8, article ID e0009571, 13p, 2021

    Toxocariasis is worldwide endemic parasitic anthropozoonosis with high risk to those in in vulnerable populations and particularly during pregnancy and childhood. Although the prevalence of anti-Toxocara spp. antibodies has been extensively studied, risk factors of pregnant women of different age...

  9. Oral shedding of CMV and HSV-1 in hematopoietic stem cell transplantation patients

    ORAL DISEASES, v.27, n.6, p.1572-1579, 2021

    Objectives To evaluate the oral shedding of herpesviruses in patients undergoing hematopoietic stem cell transplantation (HSCT) and correlate it with oral mucositis (OM). Methods Saliva samples were collected before the HSCT and on day D + 8. Multiplex Polymerse Chain Reaction (PCR) was performed...

  10. Detection of coronavirus-2 by real-time reverse transcription polymerase chain reaction in conjunctival swabs from patients with severe form of Coronavirus disease 2019 in Sao Paulo, Brazil

    CLINICS, v.76, article ID e2913, 6p, 2021

    OBJECTIVES: To test conjunctival swabs from patients with laboratory-confirmed severe forms of coronavirus disease 2019 (COVID-19) for the presence of SARS-CoV-2 on real-time reverse-transcription polymerase chain reaction (rRT-PCR). METHODS: Fifty conjunctival swabs were collected from 50 in-pat...