Instituto de Medicina Tropical - IMT
NS1-based ELISA test efficiently detects dengue infections without cross-reactivity with Zika virus
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES, v.112, p.202-204, 2021
Objectives: The aim of this study was to achieve greater specificity of dengue virus (DENV) serological tests based on a recombinant antigen derived from non-structural protein 1 (Delta NS1) with regard to cross-reactive Zika virus (ZIKV) anti-NS1 antibody responses. This is of relevance in endem...
One Health approach on human seroprevalence of anti-Toxocara antibodies, Toxocara spp. eggs in dogs and sand samples between seashore mainland and island areas of southern Brazil
ONE HEALTH, v.13, article ID 100353, 7p, 2021
Toxocariasis, caused by Toxocara spp. nematodes, is among the top 5 neglected parasitic diseases worldwide; however, no comprehensive study to date has serologically compared infections in people and their dogs and environmentally contaminated soil or sand of mainland and island locations. Accord...
Detection of SARS-CoV-2 on conjunctiva by rRT-PCR in patients with severe form of COVID-19
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, v.62, n.8, 2021
CHOLESTEROL ESTER TRANSFER PROTEIN (CETP) EXPRESSION IN MICE PROMOTES CONTROL OF EXPERIMENTAL CUTANEOUS LEISHMANIASIS
ATHEROSCLEROSIS, v.331, p.E139-E140, 2021
Disparity between scientific accomplishment and biotechnology availability in Brazil
SCIENCE PROGRESS, v.104, n.2, article ID 368504211028373, 3p, 2021
Despite being among the world's leaders in scientific output, Brazil ranks 66th among countries in the production of reagents and supplies needed for state-of-the-art scientific analyses. The production of needed reagents and equipment for experimental analyses and patient diagnostics is sorely l...
Low prevalence of human gammaherpesvirus 8 (HHV-8) infection among HIV-infected pregnant women in Rio De Janeiro, Brazil
JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE, v.34, n.20, p.3458-3461, 2021
Pregnant women coinfected with the human immunodeficiency virus (HIV) and human gammaherpesvirus 8 (HHV-8) are at higher risk of Kaposi's sarcoma development, increased viral load, and vertical transmission of these viruses. A total of 131 pregnant women infected with HIV were examined for antibo...
Latent and active tuberculosis infection in allogeneic hematopoietic stem cell transplant recipients: a prospective cohort study
BONE MARROW TRANSPLANTATION, v.56, n.9, p.2241-2247, 2021
Tuberculosis (TB) is a major infectious complication in hematopoietic stem cell transplant (HSCT) recipients in countries with high TB prevalence. Identifying and treating latent tuberculosis infection (LTBI) helps to prevent TB reactivation after transplantation. Few studies have compared the tu...
Serosurvey of anti-Toxocara antibodies and risk factors in adolescent and adult pregnant women of southeastern Brazil
PLOS NEGLECTED TROPICAL DISEASES, v.15, n.8, article ID e0009571, 13p, 2021
Toxocariasis is worldwide endemic parasitic anthropozoonosis with high risk to those in in vulnerable populations and particularly during pregnancy and childhood. Although the prevalence of anti-Toxocara spp. antibodies has been extensively studied, risk factors of pregnant women of different age...
Oral shedding of CMV and HSV-1 in hematopoietic stem cell transplantation patients
ORAL DISEASES, v.27, n.6, p.1572-1579, 2021
Objectives To evaluate the oral shedding of herpesviruses in patients undergoing hematopoietic stem cell transplantation (HSCT) and correlate it with oral mucositis (OM). Methods Saliva samples were collected before the HSCT and on day D + 8. Multiplex Polymerse Chain Reaction (PCR) was performed...
Detection of coronavirus-2 by real-time reverse transcription polymerase chain reaction in conjunctival swabs from patients with severe form of Coronavirus disease 2019 in Sao Paulo, Brazil
CLINICS, v.76, article ID e2913, 6p, 2021
OBJECTIVES: To test conjunctival swabs from patients with laboratory-confirmed severe forms of coronavirus disease 2019 (COVID-19) for the presence of SARS-CoV-2 on real-time reverse-transcription polymerase chain reaction (rRT-PCR). METHODS: Fifty conjunctival swabs were collected from 50 in-pat...