Instituto de Medicina Tropical - IMT

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O Instituto de Medicina Tropical de São Paulo (IMTSP) foi criado em 1959 para desenvolver pesquisas e fornecer subsídio científico e tecnológico para o diagnóstico, tratamento, controle e prevenção das doenças tropicais e grandes endemias do nosso país. Durante 40 anos o IMTSP esteve ligado à Faculdade de Medicina da Universidade de São Paulo, mas, a partir de dezembro de 2000, tornou-se uma unidade autônoma, um Instituto Especializado da USP.

As pesquisas no IMTSP abrangem diversos aspectos da ciência médica nessa área, como o diagnóstico, a patogenia e o tratamento, voltando-se também para as questões epidemiológicas e de prevenção. O IMTSP, além de instituição de pesquisa, também é um centro de formação, de aperfeiçoamento e de prestação de serviços especializados na área: possui um curso regular de extensão sobre saúde dos viajantes, para a comunidade externa e no 2º semestre de 2007 teve o curso de Pós-Graduação em Medicina Tropical e Saúde Internacional aprovado pela Capes.

Site oficial: http://www.imt.usp.br/

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Recent Submissions

  1. Complexity of malaria transmission dynamics in the Brazilian Atlantic Forest

    CURRENT RESEARCH IN PARASITOLOGY & VECTOR-BORNE DISEASES, v.1, article ID 100032, 8p, 2021

    Plasmodium malariae and Plasmodium vivax are protozoan parasites that can cause malaria in humans. They are genetically indistinguishable from, respectively, Plasmodium brasilianum and Plasmodium simium, i.e. parasites infecting New World non-human primates in South America. In the tropical rainf...

  2. New Allele-Specific Oligonucleotide (ASO) amplifications for Toxoplasma gondii rop18 allele typing: Analysis of 86 human congenital infections in Brazil

    ACTA TROPICA, v.247, article ID 107011, 8p, 2023

    This study aimed to detect and differentiate Toxoplasma gondii by the allele typing of its polymorphic rop18 gene. For this purpose, a novel genotyping system using allele-specific oligonucleotides (ASOs) was designed, consisting of three ASO pairs. The first and third pairs specifically amplify ...

  3. Arbovirus Surveillance in a Private Brazilian Hospital: A Four-Year Retrospective Study

    JOURNAL OF MOLECULAR DIAGNOSTICS, v.21, n.6, p.1160-1160, 2019

  4. Hemocromatose hereditária

    Evangelista, Andreia Silva; Nakhle, Maria Cristina; Cançado, Eduardo Luiz Rachid. Hemocromatose hereditária. In: Pinho, João Renato Rebello; Ribeiro Junior, Ulysses (eds). Genômica e marcadores moleculares em gastroenterologia e hepatologia. SÃO PAULO: Sarvier, 2017. p.364-373.

  5. Technical comparison of MinIon and Illumina technologies for genotyping Chikungunya virus in clinical samples

    JOURNAL OF GENETIC ENGINEERING AND BIOTECHNOLOGY, v.21, n.1, article ID 88, 8p, 2023

    New-generation sequencing (NGS) techniques have brought the opportunity for genomic monitoring of several microorganisms potentially relevant to public health. The establishment of different methods with different mechanisms provides a wide choice, taking into account several aspects. With that i...

  6. Deep serological profiling of the <i>Trypanosoma cruzi</i> TSSA antigen reveals different epitopes and modes of recognition by Chagas disease patients

    PLOS NEGLECTED TROPICAL DISEASES, v.17, n.8, article ID e0011542, 22p, 2023

    BackgroundTrypanosoma cruzi, the agent of Chagas disease, displays a highly structured population, with multiple strains that can be grouped into 6-7 evolutionary lineages showing variable eco-epidemiological traits and likely also distinct disease-associated features. Previous works have shown t...

  7. Population-based genomic study of<i> Plasmodium</i><i> vivax</i> malaria in seven Brazilian states and across South America

    LANCET REGIONAL HEALTH-AMERICAS, v.18, article ID 100420, 21p, 2023

    Background Brazil is a unique and understudied setting for malaria, with complex foci of transmission associated with human and environmental conditions. An understanding of the population genomic diversity of P. vivax parasites across Brazil can support malaria control strategies.Methods Through...

  8. Characterization of Torquetenovirus in amniotic fluid at the time of <i>in utero</i> fetal surgery: correlation with early premature delivery and respiratory distress

    FRONTIERS IN MEDICINE, v.10, article ID 1161091, 8p, 2023

    Torquetenovirus (TTV) is a commensal virus present in many healthy individuals. Although considered to be non-pathogenic, its presence and titer have been shown to be indicative of altered immune status in individuals with chronic infections or following allogeneic transplantations. We evaluated ...

  9. Association between development of severe COVID-19 and a polymorphism in the <i>CIAS1</i> gene that codes for an inflammasome component

    SCIENTIFIC REPORTS, v.13, n.1, article ID 11252, 5p, 2023

    An elevated pro-inflammatory cytokine response is associated with severe life-threatening symptoms in individuals with Coronavirus Disease-2019 (COVID). The inflammasome is an intracellular structure responsible for generation of interleukin (IL)-1 & beta; and IL-18. NALP3, a product of the CIAS1...

  10. Detailed characterization of Redondovirus in saliva of SARS-CoV-2-infected individuals in Sao Paulo, Brazil

    PLOS ONE, v.18, n.8, article ID e0291027, 10p, 2023

    BackgroundRedondovirus (ReDoV) is a DNA virus present in the respiratory tract of many healthy individuals. Since SARS-CoV-2, the virus responsible for COVID-19, also primarily infects the same site, we evaluated whether ReDoV was present at increased frequency in patients with COVID-19 and influ...