Pulmonary metastasectomy from head and neck tumors

Nenhuma Miniatura disponível
Citações na Scopus
7
Tipo de produção
article
Data de publicação
2012
Scopus
Web of Science
PubMed
Título da Revista
ISSN da Revista
Título do Volume
Editora
EDIZIONI MINERVA MEDICA
Autores
FARES, A. L.
SARDENBERG, R. A. Silva
GROSS, J. L.
Citação
MINERVA CHIRURGICA, v.67, n.3, p.227-234, 2012
Projetos de Pesquisa
Unidades Organizacionais
Fascículo
Resumo
Aim. Isolated pulmonary metastases from head and neck cancer occur in 20%-30% of patients affected by head and neck neoplams. Surgical resection is well accepted as a standard approach to treat metastases from head and neck cancer isolated to the lungs. Many studies reported overall five-year survival ranging from 20% to 30%. The aim of this study is to determine demographics and clinical treatment-related variables associated with long-term (60-month) overall survival in patients with lung metastases undergoing pulmonary metastasectomy from head and neck tumors. Methods. A retrospective review was performed of patients who were admitted with lung metastases and underwent thoracotomy for resection after treatment of the primary tumor. Data were collected regarding primary tumor features, demographics, treatment, and outcome. Results. Median follow-up time of all patients was 36.4 months (range: 0-288 months). The postoperative complication rate was 14.4%, and the 30-day mortality rate was 0%. The 60-month overall survival rate for all patients was 35.5%. Multivariate analysis identified the number of nodules at CT scan, the disease-free interval, and histological type as independent prognostic factors for overall survival. Conclusion. Lung metastasectomy is a safe and potentially curative procedure for patients with treated primary tumors. A select group of patients can achieve long-term survival after lung resection.
Palavras-chave
Lung neoplasms, Head and Neck neoplasms, Metastasectomy
URI
https://observatorio.fm.usp.br/handle/OPI/1299
Referências
  1. Beech TJ, 2010, CLIN OTOLARYNGOL, V35, P474, DOI 10.1111/j.1749-4486.2010.02198.x
  2. Berger DH, 1995, MD ANDERSON SURG ONC, P440
  3. Chen F, 2008, WORLD J SURG, V32, P1657, DOI 10.1007/s00268-008-9631-8
  4. Cohen EEW, 2003, J CLIN ONCOL, V21, P1980, DOI 10.1200/JCO.2003.10.051
  5. COX DR, 1972, J ROY STAT SOC B, V34, P187
  6. Edge SB, 2010, AJCC AM JOINT COMMIT
  7. Ercan S, 2004, ANN THORAC SURG, V77, P1786, DOI 10.1016/S0003-4975(03)01200-1
  8. Geurts TW, 2009, HEAD NECK-J SCI SPEC, V31, P220, DOI 10.1002/hed.20952
  9. Girard P, 1997, EUR J CARDIO-THORAC, V12, P385, DOI 10.1016/S1010-7940(97)00203-0
  10. KAPLAN EL, 1958, J AM STAT ASSOC, V53, P457, DOI 10.2307/2281868
  11. Kirby AM, 2006, BRIT J CANCER, V94, P631, DOI 10.1038/sj.bjc.6602999
  12. Leong PP, 1998, J NATL CANCER I, V90, P972, DOI 10.1093/jnci/90.13.972
  13. Liu D, 1999, ANN SURG ONCOL, V6, P572, DOI 10.1007/s10434-999-0572-8
  14. Margaritora S, 2002, EUR J CARDIO-THORAC, V21, P1111, DOI 10.1016/S1010-7940(02)00119-7
  15. Pastorino U, 1997, J THORAC CARDIOV SUR, V113, P37, DOI 10.1016/S0022-5223(97)70397-0
  16. Pastorino U, 2003, J THORAC CARDIOV SUR, V126, P1906, DOI 10.1016/S0022-5223(03)00211-3
  17. Petrella F, 2009, EUR J CARDIO-THORAC, V35, P792, DOI 10.1016/j.ejcts.2009.01.011
  18. Pfannschmidt J, 2006, ANN THORAC SURG, V81, P448, DOI 10.1016/j.athoracsur.2005.08.049
  19. Rena O, 2006, EUR J CARDIO-THORAC, V30, P217, DOI 10.1016/j.ejcts.2006.04.032
  20. Robert JH, 1998, CRIT REV ONCOL HEMAT, V28, P91, DOI 10.1016/S1040-8428(98)00016-X
  21. Shiono S, 2009, ANN THORAC SURG, V88, P856, DOI 10.1016/j.athoracsur.2009.04.040
  22. Tanaka Y, 2008, EUR J CARDIO-THORAC, V33, P1135, DOI 10.1016/j.ejcts.2008.03.002
  23. Vermorken JB, 2007, J CLIN ONCOL, V25, P2171, DOI 10.1200/JCO.2006.06.7447
  24. Veronesi G, 2007, J THORAC CARDIOV SUR, V133, P967, DOI 10.1016/j.jtcvs.2006.09.104
  25. Wedman J, 1996, HEAD NECK-J SCI SPEC, V18, P311, DOI 10.1002/(SICI)1097-0347(199607/08)18:4<311::AID-HED1>3.0.CO;2-0
  26. Winter H, 2008, ANN SURG ONCOL, V15, P2915, DOI 10.1245/s10434-008-0001-4
  27. Yano T, 2009, SURG TODAY, V39, P91, DOI 10.1007/s00595-008-3820-9
  28. Younes RN, 2010, REV SOC BRASILEIRA C, V12, P40
  29. Younes RN, 1997, AM J SURG, V174, P499
  30. Younes R N, 1998, Rev Assoc Med Bras, V44, P218
  31. Younes RN, 2009, CLINICS, V64, P535, DOI 10.1590/S1807-59322009000600008

Coleções
Artigos e Materiais de Revistas Científicas - HC/ICHC
Artigos e Materiais de Revistas Científicas - LIM/62