Salvage robotic prostatectomy for radio recurrent prostate cancer: technical challenges and outcome analysis

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Citações na Scopus
35
Tipo de produção
article
Data de publicação
2017
Título da Revista
ISSN da Revista
Título do Volume
Editora
EDIZIONI MINERVA MEDICA
Autores
ZARGAR, Homayoun
LAMB, Alastair D.
ROCCO, Bernardo
PORPIGLIA, Francesco
LIATSIKOS, Evangelos
DAVIS, John
POW-SANG, Julio M.
PATEL, Vipul R.
MURPHY, Declan G.
Citação
MINERVA UROLOGICA E NEFROLOGICA, v.69, n.1, p.26-37, 2017
Projetos de Pesquisa
Unidades Organizacionais
Fascículo
Resumo
INTRODUCTION: The published data on salvage robot assisted radical prostatectomy (sRARP) is limited. Our aim was to perform a systematic review of the literature on sRARP after radiation failure in patients with prostate cancer and systematically analyse the available evidence for operative and oncological outcomes. EVIDENCE ACQUISITION: A systematic review of the literature using Pubmed, Scopus, Cochrane library and ScienceDirect databases was performed in June 2016 using medical subject headings and free-text protocol. The search was conducted by applying the following search terms: salvage therapy, salvage, prostatectomy and robotics. EVIDENCE SYNTHESIS: We report on ten case series including 197 men undergoing sRARP after varying modalities of radiotherapy. Over two thirds are recurrence free at the time of follow-up but with continence rates of only 60% and potency rates of only 26%. Complications requiring intervention are few at 16% though higher than primary RARP. CONCLUSIONS: sRARP is increasingly acceptable as a treatment modality to be offered to men who fail initial radiation treatment but should be accompanied by appropriate counselling regarding the potential functional outcomes and complications. Series with longer follow-up will be helpful to assess the durability of oncological outcomes while improvements in patient selection and adaption of meticulous surgical technique around the apex could improve continence rates. The concept of concomitant extended PLND remains an issue for debate and the experience with this approach at the time of sRARP and its benefit need further scrutiny.
Palavras-chave
Prostatectomy, Surgery, computer-assisted, Prostatic neoplasms, Biochemical processes, Radiotherapy
Referências
  1. Abdollah F, 2015, EUR UROL, V67, P212, DOI 10.1016/j.eururo.2014.05.011
  2. Abdul-Muhsin H, 2013, BJU INT, V111, P686, DOI 10.1111/bju.12073
  3. Bates AS, 2015, EJSO-EUR J SURG ONC, V41, P1540, DOI 10.1016/j.ejso.2015.06.002
  4. Bolla M, 2010, LANCET ONCOL, V11, P1066, DOI 10.1016/S1470-2045(10)70223-0
  5. Boris RS, 2009, BJU INT, V103, P952, DOI 10.1111/j.1464-410X.2008.08245.x
  6. Chade DC, 2012, EUR UROL, V61, P961, DOI 10.1016/j.eururo.2012.01.022
  7. Chauhan S, 2011, J ENDOUROL, V25, P1013, DOI 10.1089/end.2010.0564
  8. Cox JD, 1997, INT J RADIAT ONCOL, V37, P1035
  9. Crook J, 2000, INT J RADIAT ONCOL, V48, P355, DOI 10.1016/S0360-3016(00)00637-4
  10. Crook JM, 2009, CANCER, V115, P673, DOI 10.1002/cncr.24020
  11. D'Amico AV, 2005, J CLIN ONCOL, V23, P4975, DOI 10.1200/JCO.2005.08.904
  12. Eandi JA, 2010, J UROLOGY, V183, P133, DOI 10.1016/j.juro.2009.08.134
  13. Gabriele D, 2016, RADIAT ONCOL, V11, DOI 10.1186/s13014-016-0599-5
  14. Gnanapragasam VJ, 2016, BJU INT
  15. Herlemann A, 2016, EUR UROL
  16. Jamal K, 2008, UROLOGY, V72, P1356, DOI 10.1016/j.urology.2008.04.007
  17. Kaffenberger SD, 2013, J UROLOGY, V189, P507, DOI 10.1016/j.juro.2012.09.057
  18. Kaouk JH, 2008, BJU INT, V102, P93, DOI 10.1111/j.1464-410X.2008.07570.x
  19. Kumar AMS, 2015, J CONTEMP BRACHYTHER, V7, P241, DOI 10.5114/jcb.2015.54050
  20. Matei DV, 2015, UROL INT, V94, P373, DOI 10.1159/000371893
  21. Mateo J, 2015, NEW ENGL J MED, V373, P1697, DOI 10.1056/NEJMoa1506859
  22. Maurer T, 2016, NAT REV UROL, V13, P226, DOI 10.1038/nrurol.2016.26
  23. Moher D, 2009, BMJ-BRIT MED J, V339, DOI 10.1136/bmj.b2535
  24. Moschini M, 2016, EUR UROL, V69, P193, DOI 10.1016/j.eururo.2015.07.047
  25. NEERHUT GJ, 1988, J UROLOGY, V140, P544
  26. Novara G, 2010, EUR UROL, V57, P363, DOI 10.1016/j.eururo.2009.11.032
  27. [Anonymous], 2009, LEVELS EVIDENCE
  28. Perera M, 2016, EUR UROL
  29. Petraki CD, 2007, HISTOL HISTOPATHOL, V22, P107, DOI 10.14670/HH-22.107
  30. Roach M, 2006, INT J RADIAT ONCOL, V65, P965, DOI 10.1016/j.ijrobp.2006.04.029
  31. Rocco B, 2012, CURR UROL REP, V13, P195, DOI 10.1007/s11934-012-0245-1
  32. Sooriakumaran P, 2014, BMJ-BRIT MED J, V348, DOI 10.1136/bmj.g1502
  33. Strope SA, 2010, J ENDOUROL, V24, P425, DOI 10.1089/end.2009.0143
  34. Vallancien G, 2003, J UROLOGY, V170, P1838, DOI 10.1097/01.ju.0000091875.24816.6b
  35. van Leeuwen PJ, 2016, BJU INT
  36. Vora A, 2016, PROSTATE INT, V4, P7, DOI 10.1016/j.prnil.2015.11.002
  37. Yuh B, 2014, BJU INT, V113, P769, DOI 10.1111/bju.12595
  38. Zugor V, 2014, UROL INT, V92, P20, DOI 10.1159/000351948