Full-length genomic sequence of hepatitis B virus genotype C2 isolated from a native Brazilian patient
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Citações na Scopus
4
Tipo de produção
article
Data de publicação
2011
Título da Revista
ISSN da Revista
Título do Volume
Editora
FUNDACO OSWALDO CRUZ
Autores
SANTANA, Rubia Anita Ferraz
SITNIK, Roberta
FERREIRA, Paulo Roberto Abrao
MANGUEIRA, Cristovao Luis Pitangueira
Citação
MEMORIAS DO INSTITUTO OSWALDO CRUZ, v.106, n.4, p.495-498, 2011
Resumo
The hepatitis B virus (HBV) is among the leading causes of chronic hepatitis, cirrhosis and hepatocellular carcinoma. In Brazil, genotype A is the most frequent, followed by genotypes D and F. Genotypes B and C are found in Brazil exclusively among Asian patients and their descendants. The aim of this study was to sequence the entire HBV genome of a Caucasian patient infected with HBV/C2 and to infer the origin of the virus based on sequencing analysis. The sequence of this Brazilian isolate was grouped with four other sequences described in China. The sequence of this patient is the first complete genome of HBV/C2 reported in Brazil.
Palavras-chave
hepatitis B virus, genotype C2, China, bayesian analyses, complete genome, Brazilian patient
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