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| DC Field | Value | Language |
|---|---|---|
| dc.contributor | Sistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP | - |
| dc.contributor.author | LEHNEN, Alexandre M. | - |
| dc.contributor.author | RODRIGUES, Bruno | - |
| dc.contributor.author | IRIGOYEN, Maria Claudia | - |
| dc.contributor.author | ANGELIS, Katia De | - |
| dc.contributor.author | SCHAAN, Beatriz D'Agord | - |
| dc.date.accessioned | 2013-09-23T16:53:36Z | - |
| dc.date.available | 2013-09-23T16:53:36Z | - |
| dc.date.issued | 2013 | - |
| dc.identifier.citation | JOURNAL OF DIABETES RESEARCH, article ID 761314, 11p, 2013 | - |
| dc.identifier.issn | 2314-6745 | - |
| dc.identifier.uri | https://observatorio.fm.usp.br/handle/OPI/2376 | - |
| dc.description.abstract | Metabolic syndrome has been defined as a group of risk factors that directly contribute to the development of cardiovascular disease and/or type 2 diabetes. Insulin resistance seems to have a fundamental role in the genesis of this syndrome. Over the past years to the present day, basic and translational research has used small animal models to explore the pathophysiology of metabolic syndrome and to develop novel therapies that might slow the progression of this prevalent condition. In this paper we discuss the animal models used for the study of metabolic syndrome, with particular focus on cardiovascular changes, since they are the main cause of death associated with the condition in humans. | - |
| dc.language.iso | eng | - |
| dc.publisher | HINDAWI PUBLISHING CORPORATION | - |
| dc.relation.ispartof | Journal of Diabetes Research | - |
| dc.rights | openAccess | - |
| dc.subject.other | obese zucker rats | - |
| dc.subject.other | sympathetic-nerve activity | - |
| dc.subject.other | spontaneously hypertensive-rats | - |
| dc.subject.other | fructose-fed rats | - |
| dc.subject.other | high-fat diet | - |
| dc.subject.other | insulin-resistance syndrome | - |
| dc.subject.other | type-2 diabetes-mellitus | - |
| dc.subject.other | renin-angiotensin system | - |
| dc.subject.other | goto-kakizaki rats | - |
| dc.subject.other | diastolic dysfunction | - |
| dc.title | Cardiovascular Changes in Animal Models of Metabolic Syndrome | - |
| dc.type | article | - |
| dc.rights.holder | Copyright HINDAWI PUBLISHING CORPORATION | - |
| dc.identifier.doi | 10.1155/2013/761314 | - |
| dc.subject.wos | Endocrinology & Metabolism | - |
| dc.subject.wos | Medicine, Research & Experimental | - |
| dc.type.category | original article | - |
| dc.type.version | publishedVersion | - |
| hcfmusp.author.external | LEHNEN, Alexandre M.:Fdn Univ Cardiol Rio Grande Sul, Anim Expt Lab, Inst Cardiol Rio Grande Sul, Porto Alegre, RS, Brazil; Fdn Univ Cardiol Rio Grande Sul, Lab Cardiol Celular & Mol, Inst Cardiol Rio Grande Sul, Porto Alegre, RS, Brazil; Univ Fed Rio Grande do Sul, Div Endocrinol, Hosp Clin Porto Alegre, Porto Alegre, RS, Brazil | - |
| hcfmusp.author.external | RODRIGUES, Bruno:Univ Sao Judas Tadeu, Lab Movimento Humano, Sao Paulo, Brazil | - |
| hcfmusp.author.external | ANGELIS, Katia De:Univ Nove Julho, Lab Fisiol Translac, Sao Paulo, Brazil | - |
| hcfmusp.author.external | SCHAAN, Beatriz D'Agord:Univ Fed Rio Grande do Sul, Div Endocrinol, Hosp Clin Porto Alegre, Porto Alegre, RS, Brazil | - |
| hcfmusp.description.articlenumber | 761314 | - |
| hcfmusp.description.volume | 2013 | - |
| hcfmusp.origem | WOS | - |
| hcfmusp.origem.id | WOS:000318639400001 | - |
| hcfmusp.origem.id | 2-s2.0-84879375034 | - |
| hcfmusp.publisher.city | NEW YORK | - |
| hcfmusp.publisher.country | USA | - |
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| dc.description.index | MEDLINE | - |
| hcfmusp.citation.scopus | 34 | - |
| hcfmusp.scopus.lastupdate | 2024-04-12 | - |
| Appears in Collections: | Artigos e Materiais de Revistas Científicas - HC/InCor Artigos e Materiais de Revistas Científicas - LIM/59 Artigos e Materiais de Revistas Científicas - ODS/03 | |
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