Please use this identifier to cite or link to this item:
https://observatorio.fm.usp.br/handle/OPI/24036
Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor | Sistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP | - |
dc.contributor.author | APPENZELLER, Simone | - |
dc.contributor.author | SOUZA, Fernando H. C. | - |
dc.contributor.author | SOUZA, Alexandre Wagner Silva de | - |
dc.contributor.author | SHOENFELD, Yehuda | - |
dc.contributor.author | CARVALHO, Jozelio Freire de | - |
dc.date.accessioned | 2017-11-27T16:42:50Z | - |
dc.date.available | 2017-11-27T16:42:50Z | - |
dc.date.issued | 2011 | - |
dc.identifier.citation | SEMINARS IN ARTHRITIS AND RHEUMATISM, v.41, n.3, p.517-523, 2011 | - |
dc.identifier.issn | 0049-0172 | - |
dc.identifier.uri | https://observatorio.fm.usp.br/handle/OPI/24036 | - |
dc.description.abstract | Objective: To perform a systematic review of the association between antiphospholipid antibodies, antiphospholipid syndrome (APS), and HELLP syndrome (Hemolysis; Elevated Liver enzymes; Low Platelet count), describing clinical features, outcome, pathophysiological findings, and treatment. Methods: We performed a literature search in PubMed using the following MeSH entry terms: HELLP syndrome, anticardiolipin antibodies, lupus anticoagulant, antiphospholipid antibodies, and antiphospholipid syndrome. We limited our search to articles published in the English literature from 1994 to 2010. Results: We identified 29 case reports/studies including a total of 51 pregnancies with HELLP syndrome in 50 patients. The majority of the cases occurred during the 28 to 36 weeks of pregnancy. Nausea, vomiting, epigastric, or right upper quadrant pain was the most frequently reported symptoms at disease onset. Elevated liver enzymes and low platelet count were reported in all studies. Concomitant hypertension and proteinuria were reported in 2/3 of the patients. Hepatic infarctions were observed in 33.3% pregnancies. However, thrombosis was also reported in the central nervous system, deep or superficial vein thrombosis, skin, intestine, bone, spleen, and adrenal glands. Treatment is still a matter of debate in HELLP syndrome. Aspirin, subcutaneous, intravenous, and oral anticoagulation, and prednisone have been used. In addition to the use of plasma exchange and fresh frozen plasma administration, intravenous immunoglobulins and plasmapheresis have been described. Conclusions: The incidence of obstetric events in patients with APS is a matter of great interest among rheumatology and gynecology and obstetrics professionals. The current knowledge that antiphospholipid antibodies/APS is not only a thrombotic disease, but also associated with microangiopathic features, can explain the greater prevalence of HELLP syndrome in these patients. | - |
dc.description.sponsorship | Fundacao Apoio A Pesquisa Estado Sao Paulo-Brasil [FAPESP 2008/02917-0, 2009/06049-6] | - |
dc.description.sponsorship | Conselho Nacional Pesquisa Desenvolvimento-Brasil CNPq [300447/2009-4] | - |
dc.description.sponsorship | Federico Foundation | - |
dc.description.sponsorship | CNPq [300665/2009-1] | - |
dc.language.iso | eng | - |
dc.publisher | W B SAUNDERS CO-ELSEVIER INC | - |
dc.relation.ispartof | Seminars in Arthritis and Rheumatism | - |
dc.rights | restrictedAccess | - |
dc.subject | antiphospholipid syndrome | - |
dc.subject | pregnancy loss | - |
dc.subject | HELLP syndrome | - |
dc.subject | eclampsia | - |
dc.subject | placental insufficiency | - |
dc.subject.other | elevated liver-enzymes | - |
dc.subject.other | systemic-lupus-erythematosus | - |
dc.subject.other | low platelets syndrome | - |
dc.subject.other | hepatic-necrosis | - |
dc.subject.other | early-onset | - |
dc.subject.other | pregnancy | - |
dc.subject.other | patient | - |
dc.subject.other | preeclampsia | - |
dc.subject.other | hemolysis | - |
dc.subject.other | infarction | - |
dc.title | HELLP Syndrome and Its Relationship with Antiphospholipid Syndrome and Antiphospholipid Antibodies | - |
dc.type | article | - |
dc.rights.holder | Copyright W B SAUNDERS CO-ELSEVIER INC | - |
dc.identifier.doi | 10.1016/j.semarthrit.2011.05.007 | - |
dc.identifier.pmid | 21868064 | - |
dc.subject.wos | Rheumatology | - |
dc.type.category | review | - |
dc.type.version | publishedVersion | - |
hcfmusp.author.external | APPENZELLER, Simone:Univ Estadual Campinas, Rheumatol Unit, Dept Med, Fac Med Sci, Sao Paulo, Brazil | - |
hcfmusp.author.external | SHOENFELD, Yehuda:Univ Fed Sao Paulo, Div Rheumatol, Sao Paulo, Brazil; Chaim Sheba Med Ctr, Dept Med B, IL-52621 Tel Hashomer, Israel | - |
hcfmusp.description.beginpage | 517 | - |
hcfmusp.description.endpage | 523 | - |
hcfmusp.description.issue | 3 | - |
hcfmusp.description.volume | 41 | - |
hcfmusp.origem | WOS | - |
hcfmusp.origem.id | 2-s2.0-84860388824 | - |
hcfmusp.origem.id | WOS:000298211800024 | - |
hcfmusp.publisher.city | PHILADELPHIA | - |
hcfmusp.publisher.country | USA | - |
hcfmusp.relation.reference | ALSULYMAN DM, 1996, OBSTET GYNECOL, V88, P644 | - |
hcfmusp.relation.reference | Amant F, 1997, LUPUS, V6, P552, DOI 10.1177/096120339700600615 | - |
hcfmusp.relation.reference | Martin JN, 2006, AM J OBSTET GYNECOL, V195, P914, DOI 10.1016/j.ajog.2005.08.044 | - |
hcfmusp.relation.reference | Segal S, 1996, EUR J OBSTET GYN R B, V68, P227, DOI 10.1016/0301-2115(96)02495-5 | - |
hcfmusp.relation.reference | Haram K, 2003, ACTA OBSTET GYN SCAN, V82, P679, DOI 10.1034/j.1600-0412.2003.00181.x | - |
hcfmusp.relation.reference | Koenig M, 2005, CLIN RHEUMATOL, V24, P166, DOI 10.1007/s10067-004-1017-1 | - |
hcfmusp.relation.reference | Miyakis S, 2006, J THROMB HAEMOST, V4, P295, DOI 10.1111/j.1538-7836.2006.01753.x | - |
hcfmusp.relation.reference | SIBAI BM, 1995, AM J OBSTET GYNECOL, V172, P125, DOI 10.1016/0002-9378(95)90099-3 | - |
hcfmusp.relation.reference | Thuong DLT, 2005, ANN RHEUM DIS, V64, P273, DOI 10.1136/ard.2003.019000 | - |
hcfmusp.relation.reference | Audibert F, 1996, AM J OBSTET GYNECOL, V175, P460, DOI 10.1016/S0002-9378(96)70162-X | - |
hcfmusp.relation.reference | Karumanchi SA, 2005, KIDNEY INT, V67, P2101, DOI 10.1111/j.1523-1755.2005.00316.x | - |
hcfmusp.relation.reference | Tripodi A, 2011, J INTERN MED, V270, P110, DOI 10.1111/j.1365-2796.2011.02362.x | - |
hcfmusp.relation.reference | George D, 2009, PROG CARDIOVASC DIS, V52, P115, DOI 10.1016/j.pcad.2009.06.005 | - |
hcfmusp.relation.reference | Sibai BM, 2003, OBSTET GYNECOL, V102, P181, DOI 10.1016/S0029-7844(03)00475-7 | - |
hcfmusp.relation.reference | Steegers EAP, 2010, LANCET, V376, P631, DOI 10.1016/S0140-6736(10)60279-6 | - |
hcfmusp.relation.reference | McMahon LP, 1997, AUST NZ J OBSTET GYN, V37, P313 | - |
hcfmusp.relation.reference | Asherson RA, 2007, ANN RHEUM DIS, V66, P429, DOI 10.1136/ard.2006.067033 | - |
hcfmusp.relation.reference | Asherson RA, 2008, CLIN RHEUMATOL, V27, P245, DOI 10.1007/s10067-007-0683-1 | - |
hcfmusp.relation.reference | Asherson RA, 2008, CLIN RHEUMATOL, V27, P1, DOI 10.1007/s10067-007-0742-7 | - |
hcfmusp.relation.reference | Asherson RA, 2007, J RHEUMATOL, V34, P1793 | - |
hcfmusp.relation.reference | Berkelhammer C, 2007, J GASTROEN HEPATOL, V22, P1695, DOI 10.1111/j.1440-1746.2007.05129.x | - |
hcfmusp.relation.reference | Braems G, 2005, EUR J OBSTET GYN R B, V123, P255, DOI 10.1016/j.ejogrb.2005.04.005 | - |
hcfmusp.relation.reference | Carp HJA, 2004, CURR OPIN OBSTET GYN, V16, P129, DOI 10.1097/01.gco.0000124163.64477.a3 | - |
hcfmusp.relation.reference | Clark Erin A S, 2007, Curr Rheumatol Rep, V9, P219, DOI 10.1007/s11926-007-0035-9 | - |
hcfmusp.relation.reference | DEGARCIA PV, 2002, OBSTET GYNECOL SURV, V57, P191 | - |
hcfmusp.relation.reference | Egerman RS, 1999, CLIN OBSTET GYNECOL, V42, P381, DOI 10.1097/00003081-199906000-00022 | - |
hcfmusp.relation.reference | Evelyn CM, 2001, JCR-J CLIN RHEUMATOL, V7, P179, DOI 10.1097/00124743-200106000-00009 | - |
hcfmusp.relation.reference | Fehr T, 2001, LUPUS, V10, P576, DOI 10.1191/096120301701549606 | - |
hcfmusp.relation.reference | George Diane, 2007, HSS J, V3, P216, DOI 10.1007/s11420-007-9043-6 | - |
hcfmusp.relation.reference | Gomez-Puerta JA, 2009, CLIN REV ALLERG IMMU, V36, P85, DOI 10.1007/s12016-008-8100-3 | - |
hcfmusp.relation.reference | HABLI M, 2009, AM J OBSTET GYNECOL, V201 | - |
hcfmusp.relation.reference | Heilmann L, 2011, SEMIN THROMB HEMOST, V37, P141, DOI 10.1055/s-0030-1270341 | - |
hcfmusp.relation.reference | HOCHFELD M, 1994, OBSTET GYNECOL, V83, P804 | - |
hcfmusp.relation.reference | ILBERY M, 1995, AUST NZ J OBSTET GYN, V35, P215, DOI 10.1111/j.1479-828X.1995.tb01877.x | - |
hcfmusp.relation.reference | Lee RM, 2003, OBSTET GYNECOL, V102, P294, DOI 10.1016/S0029-7844(03)00477-0 | - |
hcfmusp.relation.reference | Matsuda M, 2003, INTERNAL MED, V42, P1052, DOI 10.2169/internalmedicine.42.1052 | - |
hcfmusp.relation.reference | Miesbach W, 2004, CLIN RHEUMATOL, V23, P256, DOI 10.1007/s10067-004-0864-0 | - |
hcfmusp.relation.reference | Nagayama K, 1997, INTERNAL MED, V36, P661, DOI 10.2169/internalmedicine.36.661 | - |
hcfmusp.relation.reference | Neuwelt CM, 1997, ARTHRITIS RHEUM, V40, P1534, DOI 10.1002/art.1780400823 | - |
hcfmusp.relation.reference | ORNSTEIN MH, 1994, J RHEUMATOL, V21, P1360 | - |
hcfmusp.relation.reference | Pauzner R, 2003, J THROMB HAEMOST, V1, P1758, DOI 10.1046/j.1538-7836.2003.00253.x | - |
hcfmusp.relation.reference | Riviello C, 2005, THROMB RES, V115, P405, DOI 10.1016/j.thromres.2004.07.018 | - |
hcfmusp.relation.reference | Roberts G, 2003, LUPUS, V12, P251, DOI 10.1191/0961203303lu378xx | - |
hcfmusp.relation.reference | Sakhel K, 2006, SCAND J RHEUMATOL, V35, P405, DOI 10.1080/03009740600588343 | - |
hcfmusp.relation.reference | SAPONJSKI J, 2010, AUTOIMMUN REV 1121 | - |
hcfmusp.relation.reference | Sinha J, 2002, J RHEUMATOL, V29, P195 | - |
hcfmusp.relation.reference | Tsirigotis P, 2007, RHEUMATOL INT, V28, P171, DOI 10.1007/s00296-007-0386-6 | - |
hcfmusp.relation.reference | Ulander VM, 2006, LUPUS, V15, P889, DOI 10.1177/0961203306072385 | - |
hcfmusp.relation.reference | Veres K, 2008, CLIN RHEUMATOL, V27, P111, DOI 10.1007/s10067-007-0687-x | - |
hcfmusp.relation.reference | Wada Y, 2009, INTERNAL MED, V48, P1555, DOI 10.2169/internalmedicine.48.2284 | - |
hcfmusp.relation.reference | WEINSTEIN L, 1982, J OBSTET GYNAECOL, V142, P159 | - |
dc.description.index | MEDLINE | - |
dc.identifier.eissn | 1532-866X | - |
hcfmusp.citation.scopus | 51 | - |
hcfmusp.scopus.lastupdate | 2024-04-12 | - |
Appears in Collections: | Artigos e Materiais de Revistas Científicas - HC/ICHC |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
art_APPENZELLER_HELLP_Syndrome_and_Its_Relationship_with_Antiphospholipid_Syndrome_2011.PDF Restricted Access | publishedVersion (English) | 234.39 kB | Adobe PDF | View/Open Request a copy |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.