Omega 3 Consumption and Anxiety Disorders: A Cross-Sectional Analysis of the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil)

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art_NATACCI_Omega_3_Consumption_and_Anxiety_Disorders_A_CrossSectional_2018.PDF (284.51 KB)
Citações na Scopus
15
Tipo de produção
article
Data de publicação
2018
DOI
Scopus
Web of Science
PubMed
Título da Revista
ISSN da Revista
Título do Volume
Editora
MDPI
Autores
MARCHIONI, Dirce M.
NUNES, Maria Angelica
MORENO, Arlinda B.
CARDOSO, Leticia O.
GIATTI, Luana
MOLINA, Maria del Carmen B.
Citação
NUTRIENTS, v.10, n.6, article ID 663, 12p, 2018
Projetos de Pesquisa
Unidades Organizacionais
Fascículo
Resumo
Few studies have evaluated the association between diet and mental disorders, and it has been established that omega-3 (n-3) fatty acids may have a beneficial effect for sufferers of anxiety disorders. This study is part of the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil)-a population-based cohort study on diet and mental health-and searched for associations between anxiety disorders and consumption of n-3 polyunsaturated fatty acids (PUFA). The study had a cross-sectional design, with a total sample of 12,268 adults. Dietary exposure was measured by a quantitative food-frequency questionnaire, and mental diagnoses were assessed by the Clinical Interview Schedule-Revised Version and diagnosed according to the International Classification of Diseases (ICD-10). Logistic regression models were built using quintiles of n-3, omega 6 (n-6), n-6/n-3 ratio, and PUFA, using the 1st quintile as reference. Anxiety disorders were identified in 15.4% of the sample. After adjusting for sociodemographic variables, cardiovascular risk factors, diet variables, and depression, intakes in the 5th quintile were inversely associated with anxiety disorders for EPA (OR = 0.82, 95% CI = 0.69-0.98), DHA (OR = 0.83, 95% CI = 0.69-0.98), and DPA (OR = 0.82, 95% CI = 0.69-0.98). Participants in the fifth quintile of n-6/n-3 ratio had a positive association with anxiety disorders. Although results suggest a possible protective effect of n-3 fatty acids against anxiety, all associations lost significance after adjustment for multiple comparisons.
Palavras-chave
anxiety disorders, mental disorders, polyunsaturated fatty acids, omega-3 fatty acids, nutrition intake
URI
https://observatorio.fm.usp.br/handle/OPI/27993
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Coleções
Artigos e Materiais de Revistas Científicas - FM/MCM
Artigos e Materiais de Revistas Científicas - HC/IPq
Artigos e Materiais de Revistas Científicas - HU
Artigos e Materiais de Revistas Científicas - LIM/20
Artigos e Materiais de Revistas Científicas - LIM/27
Artigos e Materiais de Revistas Científicas - LIM/51