Myeloperoxidase activity and acute coronary syndrome survival: long-term evaluation in the ERICO study

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Citações na Scopus
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Tipo de produção
article
Data de publicação
2018
DOI
Scopus
Web of Science
PubMed
Título da Revista
ISSN da Revista
Título do Volume
Editora
FUTURE MEDICINE LTD
Autores
LEOCADIO, Paola Caroline Lacerda
MENTA, Penelope Lacrisio dos Reis
ALVAREZ-LEITE, Jacqueline Isaura
Citação
BIOMARKERS IN MEDICINE, v.12, n.11, p.1219-1229, 2018
Projetos de Pesquisa
Unidades Organizacionais
Fascículo
Resumo
Aim: We aimed to analyze the influence of myeloperoxidase (MPO) activity on mortality in the Acute Coronary Syndrome Registry Strategy (ERICO) study. Methods: MPO activity levels were evaluated in 342 patients. We performed survival analyses using Kaplan-Meier curves and Cox regression with respective hazard ratios, 95% CI, according to MPO tertiles distribution up to 7 years of follow-up. Results: Higher MPO activity levels were seen in men, smokers, diabetics and those who were taking aspirin. MPO activity levels were neither significant in relation to mortality nor to survival rates up to seven years. Conclusion: We found no relationship between elevated levels of MPO activity post-acute coronary syndrome and mortality up to 7-years of follow-up in the ERICO study.
Palavras-chave
acute coronary syndrome, angina, inflammation, mortality, myeloperoxidase activity, myocardial infarction, oxidative stress
URI
https://observatorio.fm.usp.br/handle/OPI/29810
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Coleções
Artigos e Materiais de Revistas Científicas - FM/MCM
Artigos e Materiais de Revistas Científicas - HC/InCor
Artigos e Materiais de Revistas Científicas - HU
Artigos e Materiais de Revistas Científicas - LIM/20
Artigos e Materiais de Revistas Científicas - LIM/51
Artigos e Materiais de Revistas Científicas - ODS/03