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DC Field | Value | Language |
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dc.contributor | Sistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP | |
dc.contributor.author | CABRAL, Norberto Luiz | |
dc.contributor.author | NAGEL, Vivian | |
dc.contributor.author | CONFORTO, Adriana B. | |
dc.contributor.author | MAGALHAES, Pedro S. C. | |
dc.contributor.author | VENANCIO, Vanessa G. | |
dc.contributor.author | SAFANELLI, Juliana | |
dc.contributor.author | IBIAPINA, Felipe | |
dc.contributor.author | MAZIN, Suleimy | |
dc.contributor.author | FRANCA, Paulo | |
dc.contributor.author | LIBERATO, Rafaela M. | |
dc.contributor.author | LONGO, Alexandre | |
dc.contributor.author | ZETOLA, Viviane F. | |
dc.date.accessioned | 2019-09-23T14:21:37Z | - |
dc.date.available | 2019-09-23T14:21:37Z | - |
dc.date.issued | 2019 | |
dc.identifier.citation | INTERNATIONAL JOURNAL OF STROKE, v.14, n.5, p.491-499, 2019 | |
dc.identifier.issn | 1747-4930 | |
dc.identifier.uri | https://observatorio.fm.usp.br/handle/OPI/33601 | - |
dc.description.abstract | Background Studies regarding long-term outcomes of ischemic stroke subtypes are scarce in low- and middle-income countries. We aimed to measure the five-year prognosis of ischemic stroke subtypes in Joinville, Brazil. Methods All first-ever ischemic strokes that occurred in Joinville in 2010 were followed-up for five years. Results We included 334 ischemic stroke patients. Over five years, 156 died, 51 had a recurrent stroke, and 128 were free of recurrent stroke. The overall cumulative risk of death was 17% (95% CI, 13% to 22%) at 30 days and 47% (95% CI, 41% to 52%) after five years. Undetermined with incomplete investigation ischemic stroke had a significantly worse survival probability (beta -4.91; 95% CI, -6.31 to -3.50; p < 0.001), followed by cardioembolic ischemic stroke (beta -3.07; 95% CI, -4.32 to -1.83; p < 0.001) and large artery disease ischemic stroke (beta -1.95; 95% CI, -3.30 to -0.60; p = 0.005). The survival probability of undetermined with negative investigation or cryptogenic ischemic stroke did not differ significantly from small artery disease ischemic stroke (beta -1.022; 95% CI, -3.37 to -1.43; p = 0.414). The five-year mortality for small artery disease ischemic stroke was 30% (95% CI, 22% to 39%) and 47% (95% CI, 35% to 60%) for large artery ischemic stroke. The risk of stroke recurrence was 2% in the first year and 5% in the second year. The proportion of disability among survivors in the first month ranged from 8% (95% CI, 3-15) for small artery disease ischemic stroke to 40% (95% CI, 30-52) for cardioembolic ischemic stroke patients. Conclusions Cardioembolic and undetermined with incomplete investigation ischemic stroke sub-types have a poor long-term prognosis. An alarming finding was that our patients with both small and large artery ischemic stroke had higher five-year mortality rates compared with subjects from high-income countries. | eng |
dc.language.iso | eng | |
dc.publisher | SAGE PUBLICATIONS LTD | eng |
dc.relation.ispartof | International Journal of Stroke | |
dc.rights | restrictedAccess | eng |
dc.subject | Ischemic stroke subtype | eng |
dc.subject | epidemiology | eng |
dc.subject | incidence | eng |
dc.subject | recurrence | eng |
dc.subject | stroke prognosis | eng |
dc.subject | survival | eng |
dc.subject.other | modified rankin scale | eng |
dc.subject.other | long-term survival | eng |
dc.subject.other | recurrence | eng |
dc.subject.other | disease | eng |
dc.title | High five-year mortality rates of ischemic stroke subtypes: A prospective cohort study in Brazil | eng |
dc.type | article | eng |
dc.rights.holder | Copyright SAGE PUBLICATIONS LTD | eng |
dc.identifier.doi | 10.1177/1747493018806197 | |
dc.identifier.pmid | 30299229 | |
dc.subject.wos | Clinical Neurology | eng |
dc.subject.wos | Peripheral Vascular Disease | eng |
dc.type.category | original article | eng |
dc.type.version | publishedVersion | eng |
hcfmusp.author.external | CABRAL, Norberto Luiz:Joinville Stroke Registry, Joinville, Brazil; Univ Regiao Joinville, Paulo Malschitzki 10, BR-89201700 Joinville, SC, Brazil | |
hcfmusp.author.external | NAGEL, Vivian:Joinville Stroke Registry, Joinville, Brazil | |
hcfmusp.author.external | MAGALHAES, Pedro S. C.:Univ Regiao Joinville, Paulo Malschitzki 10, BR-89201700 Joinville, SC, Brazil | |
hcfmusp.author.external | VENANCIO, Vanessa G.:Univ Regiao Joinville, Paulo Malschitzki 10, BR-89201700 Joinville, SC, Brazil | |
hcfmusp.author.external | SAFANELLI, Juliana:Univ Regiao Joinville, Paulo Malschitzki 10, BR-89201700 Joinville, SC, Brazil | |
hcfmusp.author.external | IBIAPINA, Felipe:Hosp Municipal Sao Jose, Joinville, Brazil | |
hcfmusp.author.external | MAZIN, Suleimy:Univ Sao Paulo, Dept Med, Ribeirao Preto, SP, Brazil | |
hcfmusp.author.external | FRANCA, Paulo:Joinville Stroke Registry, Joinville, Brazil | |
hcfmusp.author.external | LIBERATO, Rafaela M.:Univ Regiao Joinville, Paulo Malschitzki 10, BR-89201700 Joinville, SC, Brazil | |
hcfmusp.author.external | LONGO, Alexandre:Hosp Municipal Sao Jose, Joinville, Brazil | |
hcfmusp.author.external | ZETOLA, Viviane F.:Univ Fed Parana, Neurol Dept, Curitiba, Parana, Brazil | |
hcfmusp.description.beginpage | 491 | |
hcfmusp.description.endpage | 499 | |
hcfmusp.description.issue | 5 | |
hcfmusp.description.volume | 14 | |
hcfmusp.origem | WOS | |
hcfmusp.origem.id | WOS:000482445900012 | |
hcfmusp.origem.id | 2-s2.0-85059663683 | |
hcfmusp.publisher.city | LONDON | eng |
hcfmusp.publisher.country | ENGLAND | eng |
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dc.description.index | MEDLINE | eng |
dc.identifier.eissn | 1747-4949 | |
hcfmusp.citation.scopus | 7 | - |
hcfmusp.scopus.lastupdate | 2024-03-29 | - |
Appears in Collections: | Artigos e Materiais de Revistas Científicas - HC/ICHC Artigos e Materiais de Revistas Científicas - LIM/15 Artigos e Materiais de Revistas Científicas - ODS/03 |
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