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https://observatorio.fm.usp.br/handle/OPI/33973
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DC Field | Value | Language |
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dc.contributor | Sistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP | |
dc.contributor.author | SARTINI, Chiara | |
dc.contributor.author | LOMIVOROTOV, Vladimir | |
dc.contributor.author | PISANO, Antonio | |
dc.contributor.author | RIHA, Hynek | |
dc.contributor.author | REDAELLI, Martina Baiardo | |
dc.contributor.author | LOPEZ-DELGADO, Juan Carlos | |
dc.contributor.author | PIERI, Marina | |
dc.contributor.author | HAJJAR, Ludhmila | |
dc.contributor.author | FOMINSKIY, Evgeny | |
dc.contributor.author | LIKHVANTSEV, Valery | |
dc.contributor.author | CABRINI, Luca | |
dc.contributor.author | BRADIC, Nikola | |
dc.contributor.author | AVANCINI, Daniele | |
dc.contributor.author | WANG, Chew Yin | |
dc.contributor.author | LEMBO, Rosalba | |
dc.contributor.author | NOVIKOV, Maxim | |
dc.contributor.author | PATERNOSTER, Gianluca | |
dc.contributor.author | GAZIVODA, Gordana | |
dc.contributor.author | ALVARO, Gabriele | |
dc.contributor.author | ROASIO, Agostino | |
dc.contributor.author | WANG, Chengbin | |
dc.contributor.author | SEVERI, Luca | |
dc.contributor.author | PASIN, Laura | |
dc.contributor.author | MURA, Paolo | |
dc.contributor.author | MUSU, Mario | |
dc.contributor.author | SILVETTI, Simona | |
dc.contributor.author | VOTTA, Carmine Domenico | |
dc.contributor.author | BELLETTI, Alessandro | |
dc.contributor.author | CORRADI, Francesco | |
dc.contributor.author | BRUSASCO, Claudia | |
dc.contributor.author | TAMA, Simona | |
dc.contributor.author | RUGGERI, Laura | |
dc.contributor.author | YONG, Chow-Yen | |
dc.contributor.author | PASERO, Daniela | |
dc.contributor.author | MANCINO, Giuseppe | |
dc.contributor.author | SPADARO, Savino | |
dc.contributor.author | CONTE, Massimiliano | |
dc.contributor.author | LOBREGLIO, Rosetta | |
dc.contributor.author | FRAJA, Diana Di | |
dc.contributor.author | SAPORITO, Emanuela | |
dc.contributor.author | D'AMICO, Alessandro | |
dc.contributor.author | SARDO, Salvatore | |
dc.contributor.author | ORTALDA, Alessandro | |
dc.contributor.author | YAVOROVSKIY, Andrey | |
dc.contributor.author | RIEFOLO, Claudio | |
dc.contributor.author | MONACO, Fabrizio | |
dc.contributor.author | BELLOMO, Rinaldo | |
dc.contributor.author | ZANGRILLO, Alberto | |
dc.contributor.author | LANDONI, Giovanni | |
dc.date.accessioned | 2019-11-06T18:46:17Z | - |
dc.date.available | 2019-11-06T18:46:17Z | - |
dc.date.issued | 2019 | |
dc.identifier.citation | JOURNAL OF CARDIOTHORACIC AND VASCULAR ANESTHESIA, v.33, n.10, p.2685-2694, 2019 | |
dc.identifier.issn | 1053-0770 | |
dc.identifier.uri | https://observatorio.fm.usp.br/handle/OPI/33973 | - |
dc.description.abstract | Objective: Reducing mortality is a key target in critical care and perioperative medicine. The authors aimed to identify all nonsurgical interventions (drugs, techniques, strategies) shown by randomized trials to increase mortality in these clinical settings. Design: A systematic review of the literature followed by a consensus-based voting process. Setting: A web-based international consensus conference. Participants: Two hundred fifty-one physicians from 46 countries. Interventions: The authors performed a systematic literature search and identified all randomized controlled trials (RCTs) showing a significant increase in unadjusted landmark mortality among surgical or critically ill patients. The authors reviewed such studies during a meeting by a core group of experts. Studies selected after such review advanced to web-based voting by clinicians in relation to agreement, clinical practice, and willingness to include each intervention in international guidelines. Measurements and Main Results: The authors selected 12 RCTs dealing with 12 interventions increasing mortality: diaspirin-crosslinked hemoglobin (92% of agreement among web voters), overfeeding, nitric oxide synthase inhibitor in septic shock, human growth hormone, thyroxin in acute kidney injury, intravenous salbutamol in acute respiratory distress syndrome, plasma-derived protein C concentrate, aprotinin in high-risk cardiac surgery, cysteine prodrug, hypothermia in meningitis, methylprednisolone in traumatic brain injury, and albumin in traumatic brain injury (72% of agreement). Overall, a high consistency (ranging from 80% to 90%) between agreement and clinical practice was observed. Conclusion: The authors identified 12 clinical interventions showing increased mortality supported by randomized controlled trials with nonconflicting evidence, and wide agreement upon clinicians on a global scale. | eng |
dc.language.iso | eng | |
dc.publisher | W B SAUNDERS CO-ELSEVIER INC | eng |
dc.relation.ispartof | Journal of Cardiothoracic and Vascular Anesthesia | |
dc.rights | restrictedAccess | eng |
dc.subject | anesthesia | eng |
dc.subject | mortality | eng |
dc.subject | consensus conference | eng |
dc.subject | critically ill | eng |
dc.subject | perioperative | eng |
dc.subject | democracy-based medicine | eng |
dc.subject.other | intensive insulin therapy | eng |
dc.subject.other | noncardiac surgery | eng |
dc.subject.other | beta-blockade | eng |
dc.subject.other | severe sepsis | eng |
dc.subject.other | fluid resuscitation | eng |
dc.subject.other | glycemic control | eng |
dc.subject.other | clinical-trial | eng |
dc.subject.other | septic shock | eng |
dc.subject.other | ill patients | eng |
dc.subject.other | task-force | eng |
dc.title | A Systematic Review and International Web-Based Survey of Randomized Controlled Trials in the Perioperative and Critical Care Setting: Interventions Increasing Mortality | eng |
dc.type | article | eng |
dc.rights.holder | Copyright W B SAUNDERS CO-ELSEVIER INC | eng |
dc.identifier.doi | 10.1053/j.jvca.2019.03.022 | |
dc.identifier.pmid | 31064730 | |
dc.subject.wos | Anesthesiology | eng |
dc.subject.wos | Cardiac & Cardiovascular Systems | eng |
dc.subject.wos | Respiratory System | eng |
dc.subject.wos | Peripheral Vascular Disease | eng |
dc.type.category | review | eng |
dc.type.version | publishedVersion | eng |
hcfmusp.author.external | SARTINI, Chiara:IRCCS San Raffaele Sci Inst, Dept Anesthesia & Intens Care, Milan, Italy | |
hcfmusp.author.external | LOMIVOROTOV, Vladimir:E Meshalkin Natl Med Res Ctr, Novosibirsk, Russia | |
hcfmusp.author.external | PISANO, Antonio:Monaldi Hosp, Div Cardiac Anesthesia, AORN Colli, Naples, Italy; Monaldi Hosp, Intens Care Unit, Naples, Italy | |
hcfmusp.author.external | RIHA, Hynek:Inst Clin & Expt Med, Prague, Czech Republic | |
hcfmusp.author.external | REDAELLI, Martina Baiardo:IRCCS San Raffaele Sci Inst, Dept Anesthesia & Intens Care, Milan, Italy | |
hcfmusp.author.external | LOPEZ-DELGADO, Juan Carlos:Hosp Univ Bellvitge, Barcelona, Spain | |
hcfmusp.author.external | PIERI, Marina:IRCCS San Raffaele Sci Inst, Dept Anesthesia & Intens Care, Milan, Italy | |
hcfmusp.author.external | FOMINSKIY, Evgeny:IRCCS San Raffaele Sci Inst, Dept Anesthesia & Intens Care, Milan, Italy | |
hcfmusp.author.external | LIKHVANTSEV, Valery:Sechenov First Moscow State Med Univ, Dept Anesthesiol & Intens Care, Moscow, Russia; Moscow Reg Clin & Res Inst, Moscow, Russia | |
hcfmusp.author.external | CABRINI, Luca:IRCCS San Raffaele Sci Inst, Dept Anesthesia & Intens Care, Milan, Italy | |
hcfmusp.author.external | BRADIC, Nikola:Univ Hosp Dubrava, Dept Cardiovasc Anesthesiol & Cardiac Intens Med, Zagreb, Croatia | |
hcfmusp.author.external | AVANCINI, Daniele:IRCCS San Raffaele Sci Inst, San Raffaele Telethon Inst Gene Therapy SRTiget, Milan, Italy; Univ Malaya, Anaesthesia & Intens Care, Kuala Lumpur, Malaysia | |
hcfmusp.author.external | WANG, Chew Yin:St Petersburg State Univ, St Petersburg, Russia | |
hcfmusp.author.external | LEMBO, Rosalba:IRCCS San Raffaele Sci Inst, Dept Anesthesia & Intens Care, Milan, Italy | |
hcfmusp.author.external | NOVIKOV, Maxim:San Carlo Hosp, Anaesthesia & Intens Care, Potenza, Italy | |
hcfmusp.author.external | PATERNOSTER, Gianluca:Inst Cardiovasc Dis Dedinje, Belgrade, Serbia | |
hcfmusp.author.external | GAZIVODA, Gordana:AOU Mater Domini Germaneto, Catanzaro, Italy | |
hcfmusp.author.external | ALVARO, Gabriele:Osped Cardinal Massaia Asti, Dept Anaesthesia & Intens Care, Asti, Italy | |
hcfmusp.author.external | ROASIO, Agostino:Capital Med Univ, Beijing Anzhen Hosp, Ctr Anesthesiol, Beijing, Peoples R China | |
hcfmusp.author.external | WANG, Chengbin:Azienda Osped San Camillo Forlanini, Anesthesia & Intens Care, Rome, Italy | |
hcfmusp.author.external | SEVERI, Luca:S Antonio Hosp, Padua, Italy | |
hcfmusp.author.external | PASIN, Laura:Policlin Duilio Casula AOU, Dept Anesthesia & Intens Care Unit, Cagliari, Italy | |
hcfmusp.author.external | MURA, Paolo:Univ Cagliari, Dept Med Sci & Publ Hlth, Monserrato, Italy | |
hcfmusp.author.external | MUSU, Mario:IRCCS Ist Giannina Gaslini, Osped Pediat, Genoa, Italy | |
hcfmusp.author.external | SILVETTI, Simona:EO Osped Galliera, Genoa, Italy; Univ Pisa, Pisa, Italy | |
hcfmusp.author.external | VOTTA, Carmine Domenico:IRCCS San Raffaele Sci Inst, Dept Anesthesia & Intens Care, Milan, Italy | |
hcfmusp.author.external | CORRADI, Francesco:Hosp Pulau Pinang, Anaesthesia & Intens Care, Georgetown, Malaysia | |
hcfmusp.author.external | BRUSASCO, Claudia:Hosp Pulau Pinang, Anaesthesia & Intens Care, Georgetown, Malaysia | |
hcfmusp.author.external | TAMA, Simona:IRCCS San Raffaele Sci Inst, Dept Anesthesia & Intens Care, Milan, Italy | |
hcfmusp.author.external | YONG, Chow-Yen:AOU Cittadella Salute Sci, Dept Anesthesia & Intens Care, Turin, Italy | |
hcfmusp.author.external | PASERO, Daniela:Hosp Santa Chiara, Pisa, Italy | |
hcfmusp.author.external | CONTE, Massimiliano:Univ Ferrara, Intens Care Unit, Dept Morphol Surg & Expt Med, Ferrara, Italy | |
hcfmusp.author.external | LOBREGLIO, Rosetta:Mater Hosp, Bari, Italy | |
hcfmusp.author.external | ORTALDA, Alessandro:IRCCS San Raffaele Sci Inst, Dept Anesthesia & Intens Care, Milan, Italy | |
hcfmusp.author.external | RIEFOLO, Claudio:IRCCS San Raffaele Sci Inst, Dept Anesthesia & Intens Care, Milan, Italy | |
hcfmusp.author.external | BELLOMO, Rinaldo:AOU Citta Salute Sci, Anesthesia & Intens Care, Turin, Italy | |
hcfmusp.author.external | ZANGRILLO, Alberto:IRCCS San Raffaele Sci Inst, Dept Anesthesia & Intens Care, Milan, Italy; Australian & New Zealand Intens Care Res Ctr, Melbourne, Vic, Australia; Univ Vita Salute San Raffaele, Milan, Italy | |
hcfmusp.author.external | LANDONI, Giovanni:IRCCS San Raffaele Sci Inst, Dept Anesthesia & Intens Care, Milan, Italy; Australian & New Zealand Intens Care Res Ctr, Melbourne, Vic, Australia; Univ Vita Salute San Raffaele, Milan, Italy | |
hcfmusp.description.beginpage | 2685 | |
hcfmusp.description.endpage | 2694 | |
hcfmusp.description.issue | 10 | |
hcfmusp.description.volume | 33 | |
hcfmusp.origem | WOS | |
hcfmusp.origem.id | WOS:000486132300015 | |
hcfmusp.origem.id | 2-s2.0-85071057270 | |
hcfmusp.publisher.city | PHILADELPHIA | eng |
hcfmusp.publisher.country | USA | eng |
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dc.description.index | MEDLINE | eng |
dc.identifier.eissn | 1532-8422 | |
hcfmusp.citation.scopus | 9 | - |
hcfmusp.scopus.lastupdate | 2024-03-29 | - |
Appears in Collections: | Artigos e Materiais de Revistas Científicas - FM/MCP Artigos e Materiais de Revistas Científicas - HC/ICESP Artigos e Materiais de Revistas Científicas - HC/InCor Artigos e Materiais de Revistas Científicas - LIM/08 |
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