Please use this identifier to cite or link to this item:
https://observatorio.fm.usp.br/handle/OPI/39521
Title: | The global impact of SARS-CoV-2 in 181 people with cystic fibrosis |
Authors: | MCCLENAGHAN, Elliot; COSGRIFF, Rebecca; BROWNLEE, Keith; AHERN, Susannah; BURGEL, Pierre-Regis; BYRNES, Catherine A.; COLOMBO, Carla; CORVOL, Harriet; CHENG, Stephanie Y.; DANEAU, Geraldine; ELBERT, Alexander; FARO, Albert; GOSS, Christopher H.; GULMANS, Vincent; GUTIERREZ, Hector; MONESTROL, Isabelle de; JUNG, Andreas; JUSTUS, Lutz Naehrlich; KASHIRSKAYA, Nataliya; MARSHALL, Bruce C.; MCKONE, Edward; MIDDLETON, Peter G.; MONDEJAR-LOPEZ, Pedro; PASTOR-VIVERO, M. Dolores; PADOAN, Rita; RIZVI, Samar; RUSECKAITE, Rasa; SALVATORE, Marco; STEPHENSON, Anne L.; SILVA FILHO, Luiz Vicente R. da; MELO, Joel; ZAMPOLI, Marco; CARR, Siobhan B. |
Citation: | JOURNAL OF CYSTIC FIBROSIS, v.19, n.6, p.868-871, 2020 |
Abstract: | With the growing SARS-CoV-2 pandemic, we need to better understand its impact in specific patient groups like those with Cystic Fibrosis (CF). We report on 181 people with CF (32 post-transplant) from 19 countries diagnosed with SARS-CoV-2 prior to 13 June 2020. Infection with SARS-CoV-2 appears to exhibit a similar spectrum of outcomes to that seen in the general population, with 11 people admitted to intensive care (7 post-transplant), and 7 deaths (3 post-transplant). A more severe clinical course may be associated with older age, CF-related diabetes, lower lung function in the year prior to infection, and having received an organ transplant. Whilst outcomes in this large cohort are better than initially feared overall, possibly due to a protective effect of the relatively younger age of the CF population compared to other chronic conditions, SARS-CoV-2 is not a benign disease for all people in this patient group. |
Appears in Collections: | Artigos e Materiais de Revistas Científicas - COVID-19 Artigos e Materiais de Revistas Científicas - HC/ICr Artigos e Materiais de Revistas Científicas - LIM/36 Artigos e Materiais de Revistas Científicas - ODS/03 |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
art_MCCLENAGHAN_The_global_impact_of_SARSCoV2_in_181_people_2020.PDF Restricted Access | publishedVersion (English) | 344.7 kB | Adobe PDF | View/Open Request a copy |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.